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• W2759619237 endingPage "120" @default.
• W2759619237 startingPage "99" @default.
• W2759619237 abstract "Metalloporphyrins serve key roles in natural biological processes and also have demonstrated utility for biomedical applications. They can be encapsulated or grafted in conventional nanoparticles or can self-assemble themselves at the nanoscale. A wide range of metals can be stably chelated either before or after porphyrin nanoparticle formation, without the necessity of any additional chelator chemistry. The addition of metals can substantially alter a range of behaviors such as modulating phototherapeutic efficacy; conferring responsiveness to biological stimuli; or providing contrast for magnetic resonance, positron emission or surface enhanced Raman imaging. Chelated metals can also provide a convenient handle for bioconjugation with other molecules via axial coordination. This review provides an overview of some recent biomedical, nanoparticulate approaches involving gain-of-function metalloporphyrins and related molecules." @default.
• W2759619237 created "2017-10-06" @default.
• W2759619237 creator A5004070980 @default.
• W2759619237 creator A5045314927 @default.
• W2759619237 creator A5050409394 @default.
• W2759619237 date "2019-01-01" @default.
• W2759619237 modified "2023-10-17" @default.
• W2759619237 title "Metalloporphyrin nanoparticles: Coordinating diverse theranostic functions" @default.
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