Matches in SemOpenAlex for { <https://semopenalex.org/work/W2759949619> ?p ?o ?g. }
- W2759949619 endingPage "194" @default.
- W2759949619 startingPage "189" @default.
- W2759949619 abstract "Bisphenol A (BPA) is detectable in follicular fluid. However, the effect of BPA exposure on human cumulus cells (CC) that surround the oocyte and are crucial for oocyte competence has been largely unexplored. We exposed primary cultures of CC to increasing concentrations of BPA [0,0.002, 0.02 and 20μg/mL] and tested the effects of BPA on the expression of genes associated with apoptosis using quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR); we also assessed the effect of BPA on apoptosis by staining with anti-caspase 3. Exposure to 20μg/mL BPA led to significantly decreased expression of CDC20, BUB1B and HAS2 (p<0.03), increased expression of TRIB3 and LUM (p≤0.005), and increased frequency of cells positive for anti-CASP3 (p=0.03), compared to control. Our results imply that BPA may lead to ovarian toxicity by increasing CC apoptosis and provide an important molecular mechanism for the effect of BPA on human CC in vitro." @default.
- W2759949619 created "2017-10-06" @default.
- W2759949619 creator A5024075461 @default.
- W2759949619 creator A5040907031 @default.
- W2759949619 creator A5048261883 @default.
- W2759949619 creator A5048272880 @default.
- W2759949619 creator A5073491998 @default.
- W2759949619 creator A5078477921 @default.
- W2759949619 date "2017-12-01" @default.
- W2759949619 modified "2023-10-13" @default.
- W2759949619 title "Susceptibility of human cumulus cells to bisphenol a In vitro" @default.
- W2759949619 cites W1530826550 @default.
- W2759949619 cites W1975459814 @default.
- W2759949619 cites W1976178491 @default.
- W2759949619 cites W1976540956 @default.
- W2759949619 cites W1984839982 @default.
- W2759949619 cites W1986141453 @default.
- W2759949619 cites W1988980234 @default.
- W2759949619 cites W1990720544 @default.
- W2759949619 cites W2006456789 @default.
- W2759949619 cites W2029653702 @default.
- W2759949619 cites W2048047126 @default.
- W2759949619 cites W205293060 @default.
- W2759949619 cites W2065242941 @default.
- W2759949619 cites W2070325967 @default.
- W2759949619 cites W2076853816 @default.
- W2759949619 cites W2080229565 @default.
- W2759949619 cites W2087755784 @default.
- W2759949619 cites W2092750304 @default.
- W2759949619 cites W2097973787 @default.
- W2759949619 cites W2099392253 @default.
- W2759949619 cites W2107277218 @default.
- W2759949619 cites W2108113233 @default.
- W2759949619 cites W2109879710 @default.
- W2759949619 cites W2109948781 @default.
- W2759949619 cites W2116095057 @default.
- W2759949619 cites W2121204029 @default.
- W2759949619 cites W2134689931 @default.
- W2759949619 cites W2151654500 @default.
- W2759949619 cites W2153323265 @default.
- W2759949619 cites W2165796896 @default.
- W2759949619 cites W2166511379 @default.
- W2759949619 cites W2170414517 @default.
- W2759949619 cites W2279085311 @default.
- W2759949619 cites W2344764835 @default.
- W2759949619 cites W2564858831 @default.
- W2759949619 cites W2578524497 @default.
- W2759949619 cites W2735414509 @default.
- W2759949619 cites W75105120 @default.
- W2759949619 doi "https://doi.org/10.1016/j.reprotox.2017.09.008" @default.
- W2759949619 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28951153" @default.
- W2759949619 hasPublicationYear "2017" @default.
- W2759949619 type Work @default.
- W2759949619 sameAs 2759949619 @default.
- W2759949619 citedByCount "13" @default.
- W2759949619 countsByYear W27599496192018 @default.
- W2759949619 countsByYear W27599496192020 @default.
- W2759949619 countsByYear W27599496192021 @default.
- W2759949619 countsByYear W27599496192022 @default.
- W2759949619 countsByYear W27599496192023 @default.
- W2759949619 crossrefType "journal-article" @default.
- W2759949619 hasAuthorship W2759949619A5024075461 @default.
- W2759949619 hasAuthorship W2759949619A5040907031 @default.
- W2759949619 hasAuthorship W2759949619A5048261883 @default.
- W2759949619 hasAuthorship W2759949619A5048272880 @default.
- W2759949619 hasAuthorship W2759949619A5073491998 @default.
- W2759949619 hasAuthorship W2759949619A5078477921 @default.
- W2759949619 hasConcept C104317684 @default.
- W2759949619 hasConcept C150194340 @default.
- W2759949619 hasConcept C166595027 @default.
- W2759949619 hasConcept C16685009 @default.
- W2759949619 hasConcept C178790620 @default.
- W2759949619 hasConcept C185592680 @default.
- W2759949619 hasConcept C190283241 @default.
- W2759949619 hasConcept C196843134 @default.
- W2759949619 hasConcept C202751555 @default.
- W2759949619 hasConcept C2776188440 @default.
- W2759949619 hasConcept C2776690073 @default.
- W2759949619 hasConcept C2779684741 @default.
- W2759949619 hasConcept C4692481 @default.
- W2759949619 hasConcept C55493867 @default.
- W2759949619 hasConcept C71924100 @default.
- W2759949619 hasConcept C86803240 @default.
- W2759949619 hasConcept C95444343 @default.
- W2759949619 hasConceptScore W2759949619C104317684 @default.
- W2759949619 hasConceptScore W2759949619C150194340 @default.
- W2759949619 hasConceptScore W2759949619C166595027 @default.
- W2759949619 hasConceptScore W2759949619C16685009 @default.
- W2759949619 hasConceptScore W2759949619C178790620 @default.
- W2759949619 hasConceptScore W2759949619C185592680 @default.
- W2759949619 hasConceptScore W2759949619C190283241 @default.
- W2759949619 hasConceptScore W2759949619C196843134 @default.
- W2759949619 hasConceptScore W2759949619C202751555 @default.
- W2759949619 hasConceptScore W2759949619C2776188440 @default.
- W2759949619 hasConceptScore W2759949619C2776690073 @default.
- W2759949619 hasConceptScore W2759949619C2779684741 @default.
- W2759949619 hasConceptScore W2759949619C4692481 @default.
- W2759949619 hasConceptScore W2759949619C55493867 @default.