Matches in SemOpenAlex for { <https://semopenalex.org/work/W2760177029> ?p ?o ?g. }
- W2760177029 abstract "Several studies have confirmed the crucial roles of microRNAs (miRNAs) in cancer occurrence. In addition, single nucleotide polymorphisms (SNPs) in miRNA genes have been associated with various cancers. The aim of the present study was to investigate the association of SNPs in miRNA genes with cervical intraepithelial neoplasia (CIN) and cervical cancer in a Chinese Han population. We searched SNPs in nineteen miRNAs by sequencing healthy individuals (n=50). Then, a total of 400 patients with CIN, 609 patients with cervical cancer and 583 healthy individuals were recruited to genotype the SNPs using a Taqman assay. The results showed that only five of the nineteen miRNAs had SNPs (rs11134527 in pri-miR-218-2; rs74693964 in pri-miR-145; rs6062251 in pri-miR-133a2; rs531564 in pri-miR-124-1; and rs1834306 in pri-miR-100) in this Chinese Han population. The frequency of the rs11134527A allele was significantly higher in the control group than in CIN and cervical cancer groups (P=0.011 and 0.035, respectively). The frequency of the rs531564G allele was higher in the CIN and control groups than in the cervical cancer group (P=0.019 and 0.017, respectively). These results indicated that rs11134527 in pri-miR-218-2 and rs531564 in pri-miR-124-1 could be associated with CIN and cervical cancer in the Chinese Han population." @default.
- W2760177029 created "2017-10-06" @default.
- W2760177029 creator A5015131905 @default.
- W2760177029 creator A5016170808 @default.
- W2760177029 creator A5037636921 @default.
- W2760177029 creator A5061631923 @default.
- W2760177029 creator A5074400897 @default.
- W2760177029 creator A5074628946 @default.
- W2760177029 creator A5079039380 @default.
- W2760177029 creator A5082587315 @default.
- W2760177029 creator A5084737510 @default.
- W2760177029 creator A5090745605 @default.
- W2760177029 date "2017-09-23" @default.
- W2760177029 modified "2023-09-27" @default.
- W2760177029 title "The association between polymorphisms in microRNA genes and cervical cancer in a Chinese Han population" @default.
- W2760177029 cites W1175847910 @default.
- W2760177029 cites W144423133 @default.
- W2760177029 cites W1506033400 @default.
- W2760177029 cites W1606653994 @default.
- W2760177029 cites W1874592067 @default.
- W2760177029 cites W1964940696 @default.
- W2760177029 cites W1965439025 @default.
- W2760177029 cites W1965749341 @default.
- W2760177029 cites W1970571420 @default.
- W2760177029 cites W1998142094 @default.
- W2760177029 cites W1999638394 @default.
- W2760177029 cites W2004339436 @default.
- W2760177029 cites W2015721191 @default.
- W2760177029 cites W2020795819 @default.
- W2760177029 cites W2021914251 @default.
- W2760177029 cites W2026570544 @default.
- W2760177029 cites W2027025742 @default.
- W2760177029 cites W2034913624 @default.
- W2760177029 cites W2046851763 @default.
- W2760177029 cites W2052489835 @default.
- W2760177029 cites W2052642820 @default.
- W2760177029 cites W2054210950 @default.
- W2760177029 cites W2065122194 @default.
- W2760177029 cites W2066271914 @default.
- W2760177029 cites W2067435335 @default.
- W2760177029 cites W2080274706 @default.
- W2760177029 cites W2081736014 @default.
- W2760177029 cites W2082582843 @default.
- W2760177029 cites W2086620460 @default.
- W2760177029 cites W2097264828 @default.
- W2760177029 cites W2099026720 @default.
- W2760177029 cites W2101673271 @default.
- W2760177029 cites W2106787323 @default.
- W2760177029 cites W2108215484 @default.
- W2760177029 cites W2114331758 @default.
- W2760177029 cites W2116712184 @default.
- W2760177029 cites W2122033693 @default.
- W2760177029 cites W2131595467 @default.
- W2760177029 cites W2140920285 @default.
- W2760177029 cites W2143962084 @default.
- W2760177029 cites W2160859576 @default.
- W2760177029 cites W2178208931 @default.
- W2760177029 cites W2285040405 @default.
- W2760177029 cites W2335982933 @default.
- W2760177029 cites W2340672730 @default.
- W2760177029 cites W2404442880 @default.
- W2760177029 cites W2488615182 @default.
- W2760177029 cites W2509298015 @default.
- W2760177029 cites W2522617701 @default.
- W2760177029 cites W2528165927 @default.
- W2760177029 cites W2553464592 @default.
- W2760177029 cites W2559389139 @default.
- W2760177029 cites W2568218288 @default.
- W2760177029 cites W2593682592 @default.
- W2760177029 cites W2616323594 @default.
- W2760177029 cites W47682608 @default.
- W2760177029 cites W57303695 @default.
- W2760177029 doi "https://doi.org/10.18632/oncotarget.21235" @default.
- W2760177029 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5675682" @default.
- W2760177029 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29152130" @default.
- W2760177029 hasPublicationYear "2017" @default.
- W2760177029 type Work @default.
- W2760177029 sameAs 2760177029 @default.
- W2760177029 citedByCount "13" @default.
- W2760177029 countsByYear W27601770292018 @default.
- W2760177029 countsByYear W27601770292019 @default.
- W2760177029 countsByYear W27601770292020 @default.
- W2760177029 countsByYear W27601770292021 @default.
- W2760177029 crossrefType "journal-article" @default.
- W2760177029 hasAuthorship W2760177029A5015131905 @default.
- W2760177029 hasAuthorship W2760177029A5016170808 @default.
- W2760177029 hasAuthorship W2760177029A5037636921 @default.
- W2760177029 hasAuthorship W2760177029A5061631923 @default.
- W2760177029 hasAuthorship W2760177029A5074400897 @default.
- W2760177029 hasAuthorship W2760177029A5074628946 @default.
- W2760177029 hasAuthorship W2760177029A5079039380 @default.
- W2760177029 hasAuthorship W2760177029A5082587315 @default.
- W2760177029 hasAuthorship W2760177029A5084737510 @default.
- W2760177029 hasAuthorship W2760177029A5090745605 @default.
- W2760177029 hasBestOaLocation W27601770291 @default.
- W2760177029 hasConcept C104317684 @default.
- W2760177029 hasConcept C121608353 @default.
- W2760177029 hasConcept C126322002 @default.
- W2760177029 hasConcept C135763542 @default.
- W2760177029 hasConcept C139275648 @default.