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- W2760379076 abstract "An ionically hypertonic contrast medium Urografin® was inadvertently administered into the subarachnoid space of an individual and this resulted in convulsions and acute respiratory failure. We examined the effects of subarachnoid Urografin® injections on the rat central nervous system. The onset and frequency of the convulsions, as well as fatality, were dependent on the amount of Urografin® administered. No convulsions were observed in rats receiving injections of hypertonic NaCl solution or saline. The results confirmed that subarachnoid injections of Urografin® cause convulsions and death, as previously reported in human cases, and our study ascertained the causal relationship between the above malpractice and fatal outcomes." @default.
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- W2760379076 date "2017-11-01" @default.
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- W2760379076 title "Dose-dependent mortality involving convulsions due to subarachnoid Urografin® injection in rats" @default.
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- W2760379076 doi "https://doi.org/10.1016/j.legalmed.2017.09.004" @default.
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