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• W2760520374 abstract "Dengue is a mosquito-borne viral disease caused by four antigenically distinct serotypes of Dengue Virus (DENV), namely DENV1-4 and is currently considered the most important arthropod-born viral disease in the world. An effective antiviral therapy to treat Dengue Virus infection is still missing and a number of replicative cycle inhibitors are currently under study. Considering the rapid spreading of DENV and the common timeframe required for bringing a new drug on the market, the repurposing of approved drugs used for different diseases to identify novel inhibitors of this pathogen represents an attractive approach for a rapid therapeutic intervention. Herein, we will describe the most recent drug repurposing approaches to fight DENV infection and their implications in antiviral drug-discovery." @default.
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• W2760520374 date "2018-01-01" @default.
• W2760520374 modified "2023-10-10" @default.
• W2760520374 title "Drug repurposing approaches to fight Dengue virus infection and related diseases" @default.
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• W2760520374 doi "https://doi.org/10.2741/4630" @default.
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