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• W2760673044 abstract "We describe Strelka2 ( https://github.com/Illumina/strelka ), an open-source small variant calling method for clinical germline and somatic sequencing applications. Strelka2 introduces a novel mixture-model based estimation of indel error parameters from each sample, an efficient tiered haplotype modeling strategy and a normal sample contamination model to improve liquid tumor analysis. For both germline and somatic calling, Strelka2 substantially outperforms current leading tools on both variant calling accuracy and compute cost." @default.
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• W2760673044 date "2017-09-23" @default.
• W2760673044 modified "2023-10-12" @default.
• W2760673044 title "Strelka2: Fast and accurate variant calling for clinical sequencing applications" @default.
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• W2760673044 doi "https://doi.org/10.1101/192872" @default.
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