Matches in SemOpenAlex for { <https://semopenalex.org/work/W2760824416> ?p ?o ?g. }
- W2760824416 endingPage "11144" @default.
- W2760824416 startingPage "11139" @default.
- W2760824416 abstract "Significance Trace metal ions play essential roles in the function of many proteins. Examples include iron in oxygen transport, zinc in proteolytic enzymes and nucleic acid binding, and calcium in signaling and muscle contraction. Current structural methods are not optimal to detect protein-bound metals, which may be observed only after determination of the protein structure to atomic resolution. Elastic scattering contrast in annular dark-field scanning transmission electron microscopy (STEM) is particularly sensitive to atomic number. Using 3D reconstructions generated from cryo-STEM images, we detect isolated Zn and Fe bound to ferritin at very low stoichiometry. The different patterns obtained reflect physiological interactions of these metals with ferritin. The demonstration also raises the potential for specific protein labeling with heavy atoms." @default.
- W2760824416 created "2017-10-20" @default.
- W2760824416 creator A5002738485 @default.
- W2760824416 creator A5029979638 @default.
- W2760824416 creator A5039241455 @default.
- W2760824416 creator A5041695327 @default.
- W2760824416 creator A5043230243 @default.
- W2760824416 date "2017-10-02" @default.
- W2760824416 modified "2023-10-17" @default.
- W2760824416 title "Detection of isolated protein-bound metal ions by single-particle cryo-STEM" @default.
- W2760824416 cites W1586615079 @default.
- W2760824416 cites W1899986536 @default.
- W2760824416 cites W1967004359 @default.
- W2760824416 cites W1974531375 @default.
- W2760824416 cites W1981896734 @default.
- W2760824416 cites W1995803883 @default.
- W2760824416 cites W1999279640 @default.
- W2760824416 cites W2005887525 @default.
- W2760824416 cites W2006001910 @default.
- W2760824416 cites W2007179625 @default.
- W2760824416 cites W2016798351 @default.
- W2760824416 cites W2024534762 @default.
- W2760824416 cites W2030343674 @default.
- W2760824416 cites W2031539675 @default.
- W2760824416 cites W2032146255 @default.
- W2760824416 cites W2033079348 @default.
- W2760824416 cites W2039175603 @default.
- W2760824416 cites W2043351987 @default.
- W2760824416 cites W2048982317 @default.
- W2760824416 cites W2055799065 @default.
- W2760824416 cites W2056530523 @default.
- W2760824416 cites W2057219336 @default.
- W2760824416 cites W2059704335 @default.
- W2760824416 cites W2061762695 @default.
- W2760824416 cites W2072404529 @default.
- W2760824416 cites W2083595634 @default.
- W2760824416 cites W2087337738 @default.
- W2760824416 cites W2087616636 @default.
- W2760824416 cites W2088445635 @default.
- W2760824416 cites W2093669889 @default.
- W2760824416 cites W2099540110 @default.
- W2760824416 cites W2100455255 @default.
- W2760824416 cites W2104234755 @default.
- W2760824416 cites W2108816504 @default.
- W2760824416 cites W2114462637 @default.
- W2760824416 cites W2117523988 @default.
- W2760824416 cites W2123426174 @default.
- W2760824416 cites W2123738125 @default.
- W2760824416 cites W2127697948 @default.
- W2760824416 cites W2132629607 @default.
- W2760824416 cites W2146156988 @default.
- W2760824416 cites W2168312174 @default.
- W2760824416 cites W2464585291 @default.
- W2760824416 cites W2522852317 @default.
- W2760824416 cites W2529058893 @default.
- W2760824416 cites W2531833723 @default.
- W2760824416 cites W429513333 @default.
- W2760824416 doi "https://doi.org/10.1073/pnas.1708609114" @default.
- W2760824416 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5651765" @default.
- W2760824416 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28973937" @default.
- W2760824416 hasPublicationYear "2017" @default.
- W2760824416 type Work @default.
- W2760824416 sameAs 2760824416 @default.
- W2760824416 citedByCount "34" @default.
- W2760824416 countsByYear W27608244162017 @default.
- W2760824416 countsByYear W27608244162018 @default.
- W2760824416 countsByYear W27608244162019 @default.
- W2760824416 countsByYear W27608244162020 @default.
- W2760824416 countsByYear W27608244162021 @default.
- W2760824416 countsByYear W27608244162022 @default.
- W2760824416 countsByYear W27608244162023 @default.
- W2760824416 crossrefType "journal-article" @default.
- W2760824416 hasAuthorship W2760824416A5002738485 @default.
- W2760824416 hasAuthorship W2760824416A5029979638 @default.
- W2760824416 hasAuthorship W2760824416A5039241455 @default.
- W2760824416 hasAuthorship W2760824416A5041695327 @default.
- W2760824416 hasAuthorship W2760824416A5043230243 @default.
- W2760824416 hasBestOaLocation W27608244161 @default.
- W2760824416 hasConcept C104317684 @default.
- W2760824416 hasConcept C12554922 @default.
- W2760824416 hasConcept C146088050 @default.
- W2760824416 hasConcept C171250308 @default.
- W2760824416 hasConcept C178790620 @default.
- W2760824416 hasConcept C185592680 @default.
- W2760824416 hasConcept C192562407 @default.
- W2760824416 hasConcept C193016168 @default.
- W2760824416 hasConcept C24284526 @default.
- W2760824416 hasConcept C2778319317 @default.
- W2760824416 hasConcept C535196362 @default.
- W2760824416 hasConcept C544153396 @default.
- W2760824416 hasConcept C55493867 @default.
- W2760824416 hasConcept C8010536 @default.
- W2760824416 hasConcept C86339819 @default.
- W2760824416 hasConcept C86803240 @default.
- W2760824416 hasConceptScore W2760824416C104317684 @default.
- W2760824416 hasConceptScore W2760824416C12554922 @default.
- W2760824416 hasConceptScore W2760824416C146088050 @default.
- W2760824416 hasConceptScore W2760824416C171250308 @default.