FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2760870025> ?p ?o ?g. }

• W2760870025 endingPage "371" @default.
• W2760870025 startingPage "364" @default.
• W2760870025 abstract "Brain-derived neurotrophic factor (BDNF) is a neurotrophin that can promote the development and proliferation of neurons. BDNF has been found to be involved in male reproduction. Leydig cells in testicular interstitial tissues can secrete testosterone in a luteinizing hormone-dependent manner. We showed that BDNF and its receptor TrkB were expressed in mice TM3 Leydig cells in the present study. Furthermore, BDNF can promote proliferation of mouse TM3 Leydig cells in vitro. Results of microRNA (miRNA) deep sequencing showed that BDNF can alter the expression profile of miRNAs in TM3 Leydig cells. Eighty-three miRNAs were significantly different in the BDNF-treated and control groups (fold change of >2.0 or <0.5, P < 0.05) wherein 40 were upregulated and 43 were downregulated. The expression levels of miR-125a-5p, miR-22-5p, miR-342-59, miR-451a, miR-148a-5p, miR-29b-3p, miR-199b-5p, and miR-145a-5p were further confirmed by quantitative real-time polymerase chain reaction. Bioinformatic analysis revealed that miRNAs regulated a large number of genes with different functions. Pathway analysis indicated that miRNAs participate in the pathways involved in signal transduction, cancer, metabolism, endocrine system, immune system, and nerve system. This study indicated that miRNAs might be involved in the BDNF-regulated cellular functions of Leydig cells." @default.
• W2760870025 created "2017-10-20" @default.
• W2760870025 creator A5001534336 @default.
• W2760870025 creator A5009135594 @default.
• W2760870025 creator A5012880819 @default.
• W2760870025 creator A5016208356 @default.
• W2760870025 creator A5019218337 @default.
• W2760870025 creator A5023282904 @default.
• W2760870025 creator A5024081631 @default.
• W2760870025 creator A5024846006 @default.
• W2760870025 creator A5036546912 @default.
• W2760870025 creator A5062181804 @default.
• W2760870025 creator A5062583843 @default.
• W2760870025 creator A5070935951 @default.
• W2760870025 creator A5072737932 @default.
• W2760870025 creator A5083617974 @default.
• W2760870025 date "2017-10-01" @default.
• W2760870025 modified "2023-10-17" @default.
• W2760870025 title "Differential expression of microRNAs in TM3 Leydig cells of mice treated with brain-derived neurotrophic factor" @default.
• W2760870025 cites W1054473502 @default.
• W2760870025 cites W1487702440 @default.
• W2760870025 cites W1522985800 @default.
• W2760870025 cites W1567575298 @default.
• W2760870025 cites W1588326306 @default.
• W2760870025 cites W1964973107 @default.
• W2760870025 cites W1967820825 @default.
• W2760870025 cites W1969116788 @default.
• W2760870025 cites W1987920581 @default.
• W2760870025 cites W2001627085 @default.
• W2760870025 cites W2001947904 @default.
• W2760870025 cites W2007612364 @default.
• W2760870025 cites W2009608953 @default.
• W2760870025 cites W2010643654 @default.
• W2760870025 cites W2028900566 @default.
• W2760870025 cites W2029048316 @default.
• W2760870025 cites W2038641453 @default.
• W2760870025 cites W2054295952 @default.
• W2760870025 cites W2056583090 @default.
• W2760870025 cites W2062547614 @default.
• W2760870025 cites W2068181807 @default.
• W2760870025 cites W2072611515 @default.
• W2760870025 cites W2081771918 @default.
• W2760870025 cites W2084294589 @default.
• W2760870025 cites W2097617658 @default.
• W2760870025 cites W2101681543 @default.
• W2760870025 cites W2104295145 @default.
• W2760870025 cites W2106645970 @default.
• W2760870025 cites W2106994020 @default.
• W2760870025 cites W2127519248 @default.
• W2760870025 cites W2138242620 @default.
• W2760870025 cites W2140681541 @default.
• W2760870025 cites W2150734040 @default.
• W2760870025 cites W2152004432 @default.
• W2760870025 cites W2152497088 @default.
• W2760870025 cites W2160398712 @default.
• W2760870025 cites W2160998038 @default.
• W2760870025 cites W2297103981 @default.
• W2760870025 cites W2327462031 @default.
• W2760870025 cites W2360358288 @default.
• W2760870025 cites W2395505927 @default.
• W2760870025 cites W2461262317 @default.
• W2760870025 cites W2479155331 @default.
• W2760870025 cites W2524889287 @default.
• W2760870025 cites W2530152586 @default.
• W2760870025 cites W2544648818 @default.
• W2760870025 cites W4294216483 @default.
• W2760870025 doi "https://doi.org/10.1002/cbf.3283" @default.
• W2760870025 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28967682" @default.
• W2760870025 hasPublicationYear "2017" @default.
• W2760870025 type Work @default.
• W2760870025 sameAs 2760870025 @default.
• W2760870025 citedByCount "8" @default.
• W2760870025 countsByYear W27608700252018 @default.
• W2760870025 countsByYear W27608700252019 @default.
• W2760870025 countsByYear W27608700252020 @default.
• W2760870025 countsByYear W27608700252021 @default.
• W2760870025 countsByYear W27608700252022 @default.
• W2760870025 countsByYear W27608700252023 @default.
• W2760870025 crossrefType "journal-article" @default.
• W2760870025 hasAuthorship W2760870025A5001534336 @default.
• W2760870025 hasAuthorship W2760870025A5009135594 @default.
• W2760870025 hasAuthorship W2760870025A5012880819 @default.
• W2760870025 hasAuthorship W2760870025A5016208356 @default.
• W2760870025 hasAuthorship W2760870025A5019218337 @default.
• W2760870025 hasAuthorship W2760870025A5023282904 @default.
• W2760870025 hasAuthorship W2760870025A5024081631 @default.
• W2760870025 hasAuthorship W2760870025A5024846006 @default.
• W2760870025 hasAuthorship W2760870025A5036546912 @default.
• W2760870025 hasAuthorship W2760870025A5062181804 @default.
• W2760870025 hasAuthorship W2760870025A5062583843 @default.
• W2760870025 hasAuthorship W2760870025A5070935951 @default.
• W2760870025 hasAuthorship W2760870025A5072737932 @default.
• W2760870025 hasAuthorship W2760870025A5083617974 @default.
• W2760870025 hasConcept C104317684 @default.
• W2760870025 hasConcept C126322002 @default.
• W2760870025 hasConcept C127561419 @default.
• W2760870025 hasConcept C134018914 @default.
• W2760870025 hasConcept C145059251 @default.

• next