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- W2760990181 abstract "Abstract Background This study sought to characterize cognitive outcomes among Latino survivors of childhood acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LL). Procedure In this cross‐sectional cohort study, Latino survivors of ALL (n = 57) and LL (n = 5) aged 6–16 years were pooled and evaluated using validated measures of cognitive, academic, and behavioral function and English language proficiency. Performance was compared with norms using single‐sample t ‐tests. Results In this cohort ( n = 62, 50% male), mean ages at diagnosis and testing were 4.5 and 10.8 years, respectively; mean time off treatment was 44.7 months. All participants spoke English and over half (57%) identified Spanish as the primary language in the home. Forty‐two families (68%) placed in the two lowest Hollingshead socioeconomic status categories. Participants were below average for working memory ( P < 0.001). Overall, participants were in the average range, but significantly lower than published norms on domain‐specific measures of verbal comprehension ( P < 0.001); perceptual reasoning ( P = 0.033); processing speed ( P = 0.003); visual memory ( P < 0.001); visuomotor attention, scanning, and sequencing ( P = 0.005); and reading comprehension ( P = 0.001). Parents reported concerns with working memory ( P < 0.001) and metacognition ( P = 0.014). Conclusions Similar to other childhood ALL/LL survivors, overall cognitive function in this Latino sample was relatively preserved but selected deficits were observed. Routine cognitive screening is indicated in this population." @default.
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- W2760990181 date "2017-10-08" @default.
- W2760990181 modified "2023-10-17" @default.
- W2760990181 title "Cognitive outcomes among Latino survivors of childhood acute lymphoblastic leukemia and lymphoma: A cross‐sectional cohort study using culturally competent, performance‐based assessment" @default.
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- W2760990181 doi "https://doi.org/10.1002/pbc.26844" @default.
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