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- W2761417430 abstract "Purpose: To review the treatment results of cervix cancer patients treated with high dose rate brachytherapy at KingAbdul Aziz University Hospital.Methods: All cervix cancer patients treated with high dose rate brachytherapy at King Abdul Aziz university hospitalbetween January 2004 and December 2006 have been reviewed. The patient’s demographic data, treatment parametersand follow up have been reported and histopathological grade and stage has been correlated with initial responseto treatment and disease Free survival has been calculated.Results: Twenty four patients with mean age of 51.6 years. All patients had squamous cell carcinoma; 12.5% G1, 54.2%G II and 33.3% G III. Stage IA 12.5%, IB 4.2%, IIA 16.7%, IIB 25%, IIIA 8.3%, IIIB 20.8% and IVA 12.5%, treatment toxicity wasdiarrhea GII in 12.5% and G II cystitis in 21%.Initial treatment response was 50% CR, 25% PR, 8.3% SD, and 16.7% DP.After a mean follow up period of 39 months, the mean DFS was 27.3 months 95% confidence interval (CI) 23.52 – 31.07.The median DFS was 29 months (95% CI , 23 – 35 months). Two year DFS was 60% and the 3 year DFS was 27%.There was no correlation between DFS and histopathological grade (p = 0.53) or FIGO stage (p = 0.66), and no correlationwas found between DFS and response to treatment (p = 0.88). On multivariate analysis, histopathological grade,FIGO stage, initial response all had no influence on DFS.Conclusion: The use of external beam radiation therapy concomitant with weekly cisplatin followed by high dose ratebrachytherapy is an acceptable treatment modality for carcinoma of the cervix with mild treatment related toxicity" @default.
- W2761417430 created "2017-10-20" @default.
- W2761417430 creator A5031361269 @default.
- W2761417430 date "2009-01-01" @default.
- W2761417430 modified "2023-09-24" @default.
- W2761417430 title "Outcome of Cervix Cancer Patients Treated With High Dose Rate Brachytherapy" @default.
- W2761417430 hasPublicationYear "2009" @default.
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