FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2761528400> ?p ?o ?g. }

• W2761528400 endingPage "1195" @default.
• W2761528400 startingPage "1185" @default.
• W2761528400 abstract "A chemical library comprised of nineteen synthesized pyridyl disulfides that emulate the chemical reactivity of allicin (garlic) was evaluated for antimicrobial activity against a panel of pathogenic bacteria. Gram-positive species including vancomycin-intermediate and vancomycin-resistant Staphylococcus aureus (VISA, VRSA) demonstrated the highest level of susceptibility toward analogs with S-alkyl chains of 7-9 carbons in length. Further biological studies revealed that the disulfides display synergy with vancomycin against VRSA, cause dispersal of S. aureus biofilms, exhibit low cytotoxicity, and decelerate S. aureus metabolism. In final analysis, pyridyl disulfides represent a novel class of mechanism-based antibacterial agents that have a potential application as antibiotic adjuvants in combination therapy of S. aureus infections with reduced vancomycin susceptibility." @default.
• W2761528400 created "2017-10-20" @default.
• W2761528400 creator A5019634704 @default.
• W2761528400 creator A5021846790 @default.
• W2761528400 creator A5039928006 @default.
• W2761528400 creator A5059468684 @default.
• W2761528400 creator A5067703885 @default.
• W2761528400 date "2018-01-01" @default.
• W2761528400 modified "2023-10-02" @default.
• W2761528400 title "Allicin-inspired pyridyl disulfides as antimicrobial agents for multidrug-resistant Staphylococcus aureus" @default.
• W2761528400 cites W1518907982 @default.
• W2761528400 cites W1531324256 @default.
• W2761528400 cites W1884241479 @default.
• W2761528400 cites W1944045095 @default.
• W2761528400 cites W1979608829 @default.
• W2761528400 cites W1982029231 @default.
• W2761528400 cites W1982126950 @default.
• W2761528400 cites W1985311175 @default.
• W2761528400 cites W2016562927 @default.
• W2761528400 cites W2018397292 @default.
• W2761528400 cites W2032597476 @default.
• W2761528400 cites W2039045853 @default.
• W2761528400 cites W2040720195 @default.
• W2761528400 cites W2045301936 @default.
• W2761528400 cites W2056501162 @default.
• W2761528400 cites W2057910559 @default.
• W2761528400 cites W2078757278 @default.
• W2761528400 cites W2085390942 @default.
• W2761528400 cites W2103694883 @default.
• W2761528400 cites W2111691760 @default.
• W2761528400 cites W2115542273 @default.
• W2761528400 cites W2126915534 @default.
• W2761528400 cites W2127319957 @default.
• W2761528400 cites W2135702685 @default.
• W2761528400 cites W2141355399 @default.
• W2761528400 cites W2145098810 @default.
• W2761528400 cites W2147652807 @default.
• W2761528400 cites W2162209314 @default.
• W2761528400 cites W2169956813 @default.
• W2761528400 cites W2303633006 @default.
• W2761528400 cites W2529079843 @default.
• W2761528400 cites W2730199880 @default.
• W2761528400 cites W2949731935 @default.
• W2761528400 doi "https://doi.org/10.1016/j.ejmech.2017.10.018" @default.
• W2761528400 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5817985" @default.
• W2761528400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29126733" @default.
• W2761528400 hasPublicationYear "2018" @default.
• W2761528400 type Work @default.
• W2761528400 sameAs 2761528400 @default.
• W2761528400 citedByCount "29" @default.
• W2761528400 countsByYear W27615284002018 @default.
• W2761528400 countsByYear W27615284002019 @default.
• W2761528400 countsByYear W27615284002020 @default.
• W2761528400 countsByYear W27615284002021 @default.
• W2761528400 countsByYear W27615284002022 @default.
• W2761528400 countsByYear W27615284002023 @default.
• W2761528400 crossrefType "journal-article" @default.
• W2761528400 hasAuthorship W2761528400A5019634704 @default.
• W2761528400 hasAuthorship W2761528400A5021846790 @default.
• W2761528400 hasAuthorship W2761528400A5039928006 @default.
• W2761528400 hasAuthorship W2761528400A5059468684 @default.
• W2761528400 hasAuthorship W2761528400A5067703885 @default.
• W2761528400 hasBestOaLocation W27615284002 @default.
• W2761528400 hasConcept C109316439 @default.
• W2761528400 hasConcept C178790620 @default.
• W2761528400 hasConcept C185592680 @default.
• W2761528400 hasConcept C202751555 @default.
• W2761528400 hasConcept C2778980435 @default.
• W2761528400 hasConcept C2779489039 @default.
• W2761528400 hasConcept C2780104969 @default.
• W2761528400 hasConcept C2781005338 @default.
• W2761528400 hasConcept C4937899 @default.
• W2761528400 hasConcept C501593827 @default.
• W2761528400 hasConcept C523546767 @default.
• W2761528400 hasConcept C54355233 @default.
• W2761528400 hasConcept C55493867 @default.
• W2761528400 hasConcept C86803240 @default.
• W2761528400 hasConcept C89423630 @default.
• W2761528400 hasConceptScore W2761528400C109316439 @default.
• W2761528400 hasConceptScore W2761528400C178790620 @default.
• W2761528400 hasConceptScore W2761528400C185592680 @default.
• W2761528400 hasConceptScore W2761528400C202751555 @default.
• W2761528400 hasConceptScore W2761528400C2778980435 @default.
• W2761528400 hasConceptScore W2761528400C2779489039 @default.
• W2761528400 hasConceptScore W2761528400C2780104969 @default.
• W2761528400 hasConceptScore W2761528400C2781005338 @default.
• W2761528400 hasConceptScore W2761528400C4937899 @default.
• W2761528400 hasConceptScore W2761528400C501593827 @default.
• W2761528400 hasConceptScore W2761528400C523546767 @default.
• W2761528400 hasConceptScore W2761528400C54355233 @default.
• W2761528400 hasConceptScore W2761528400C55493867 @default.
• W2761528400 hasConceptScore W2761528400C86803240 @default.
• W2761528400 hasConceptScore W2761528400C89423630 @default.
• W2761528400 hasLocation W27615284001 @default.
• W2761528400 hasLocation W27615284002 @default.
• W2761528400 hasLocation W27615284003 @default.
• W2761528400 hasLocation W27615284004 @default.
• W2761528400 hasLocation W27615284005 @default.

• next