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- W276156683 abstract "The effect of hyperthermic treatments (42.5 or 45.5°C) on recovery from radiation damage has been examined. Recovery from sublethal damage (SLD) when heat was administered prior to irradiation was not inhibited by small heat treatments (survival reduced to 80% by 30 min at 42.5°C or 4 min at 45.5°C) for either temperature, but recovery was inhibited by larger heat treatments (survival reduced to 10% by 120 min at 42.5°C or 15 min at 45.5°C). Thus, the effects of 42.5 or 45.5°C on recovery from SLD were similar when the heat treatments resulting in equal survival levels were used. Recovery from potentially lethal damage (PLD), as measured by incubation at 20°C after a combination of radiation and heat treatments was observed when a small heat treatment (30 min at 42.5°C) was given either before or after irradiation. The amount of radiosensitization, i.e., the thermal enhancement ratio (TER), calculated at the survival level of 10-3 correlated with the amount of cell killing resulting from the heat exposure..." @default.
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- W276156683 date "1979-08-01" @default.
- W276156683 modified "2023-10-18" @default.
- W276156683 title "Radiosensitivity and Recovery from Radiation Damage in Cultured CHO Cells Exposed to Hyperthermia at 42.5 or 45.5°C" @default.
- W276156683 cites W2124331978 @default.
- W276156683 doi "https://doi.org/10.2307/3575104" @default.
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