FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2761609946> ?p ?o ?g. }

• W2761609946 abstract "Approximately 30% of patients with Crohn disease (CD) are unresponsive to biologics. No previous study has focused on a plant-based diet in an induction phase of CD treatment.To investigate the remission rate of infliximab combined with a plant-based diet as first-line (IPF) therapy for CD.This was a prospective single-group trial conducted at tertiary hospitals. Subjects included consecutive adults with a new diagnosis (n = 26), children with a new diagnosis (n = 11), and relapsing adults (n = 9) with CD who were naïve to treatment with biologics. Patients were admitted and administered a standard induction therapy with infliximab (5 mg/kg; 3 infusions at 0, 2, and 6 weeks). Additionally, they received a lacto-ovo-semivegetarian diet. The primary end point was remission, defined as the disappearance of active CD symptoms at week 6. Secondary end points were Crohn Disease Activity Index (CDAI) score, C-reactive protein (CRP) concentration, and mucosal healing.Two adults with a new diagnosis were withdrawn from the treatment protocol because of intestinal obstruction. The remission rates by the intention-to-treat and per-protocol analyses were 96% (44/46) and 100% (44/44), respectively. Mean CDAI score (314) on admission decreased to 63 at week 6 (p < 0.0001). Mean CRP level on admission (5.3 mg/dL) decreased to 0.2 (p < 0.0001). Mucosal healing was achieved in 46% (19/41) of cases.IPF therapy can induce remission in most patients with CD who are naïve to biologics regardless of age or whether they have a new diagnosis or relapse." @default.
• W2761609946 created "2017-10-20" @default.
• W2761609946 creator A5001257513 @default.
• W2761609946 creator A5008799011 @default.
• W2761609946 creator A5035670774 @default.
• W2761609946 creator A5071549667 @default.
• W2761609946 creator A5073860686 @default.
• W2761609946 creator A5074097572 @default.
• W2761609946 creator A5074358913 @default.
• W2761609946 creator A5078447184 @default.
• W2761609946 creator A5081011658 @default.
• W2761609946 creator A5081983682 @default.
• W2761609946 date "2017-12-01" @default.
• W2761609946 modified "2023-10-16" @default.
• W2761609946 title "Induction with Infliximab and a Plant-Based Diet as First-Line (IPF) Therapy for Crohn Disease: A Single-Group Trial" @default.
• W2761609946 cites W1706367474 @default.
• W2761609946 cites W1904655665 @default.
• W2761609946 cites W1933138048 @default.
• W2761609946 cites W1944754896 @default.
• W2761609946 cites W1968105193 @default.
• W2761609946 cites W1986125265 @default.
• W2761609946 cites W2003674978 @default.
• W2761609946 cites W2004608617 @default.
• W2761609946 cites W2025836106 @default.
• W2761609946 cites W2029352313 @default.
• W2761609946 cites W2030631780 @default.
• W2761609946 cites W2043780895 @default.
• W2761609946 cites W2048729604 @default.
• W2761609946 cites W2050431295 @default.
• W2761609946 cites W2052476019 @default.
• W2761609946 cites W2056477506 @default.
• W2761609946 cites W2059127937 @default.
• W2761609946 cites W2059332039 @default.
• W2761609946 cites W2070414885 @default.
• W2761609946 cites W2078007418 @default.
• W2761609946 cites W2079756974 @default.
• W2761609946 cites W2086050457 @default.
• W2761609946 cites W2087292184 @default.
• W2761609946 cites W2090015658 @default.
• W2761609946 cites W2094385084 @default.
• W2761609946 cites W2097979070 @default.
• W2761609946 cites W2102013054 @default.
• W2761609946 cites W2103669303 @default.
• W2761609946 cites W2105058392 @default.
• W2761609946 cites W2111570058 @default.
• W2761609946 cites W2114990062 @default.
• W2761609946 cites W2119092990 @default.
• W2761609946 cites W2121569640 @default.
• W2761609946 cites W2121609590 @default.
• W2761609946 cites W2126807394 @default.
• W2761609946 cites W2132731835 @default.
• W2761609946 cites W2143545673 @default.
• W2761609946 cites W2148567965 @default.
• W2761609946 cites W2152026434 @default.
• W2761609946 cites W2152381563 @default.
• W2761609946 cites W2152438285 @default.
• W2761609946 cites W2154622069 @default.
• W2761609946 cites W2155311724 @default.
• W2761609946 cites W2156250460 @default.
• W2761609946 cites W2160005424 @default.
• W2761609946 cites W2168654564 @default.
• W2761609946 cites W2168751860 @default.
• W2761609946 cites W2169080396 @default.
• W2761609946 cites W2169859225 @default.
• W2761609946 cites W2171896579 @default.
• W2761609946 cites W2257015069 @default.
• W2761609946 cites W2271103943 @default.
• W2761609946 cites W2275338833 @default.
• W2761609946 cites W2318409207 @default.
• W2761609946 cites W2321453230 @default.
• W2761609946 cites W2340491704 @default.
• W2761609946 cites W2384731673 @default.
• W2761609946 cites W2408830150 @default.
• W2761609946 cites W2413205046 @default.
• W2761609946 cites W2531236356 @default.
• W2761609946 cites W2793981785 @default.
• W2761609946 cites W77272352 @default.
• W2761609946 doi "https://doi.org/10.7812/tpp/17-009" @default.
• W2761609946 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5638637" @default.
• W2761609946 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29035182" @default.
• W2761609946 hasPublicationYear "2017" @default.
• W2761609946 type Work @default.
• W2761609946 sameAs 2761609946 @default.
• W2761609946 citedByCount "33" @default.
• W2761609946 countsByYear W27616099462017 @default.
• W2761609946 countsByYear W27616099462018 @default.
• W2761609946 countsByYear W27616099462019 @default.
• W2761609946 countsByYear W27616099462020 @default.
• W2761609946 countsByYear W27616099462021 @default.
• W2761609946 countsByYear W27616099462022 @default.
• W2761609946 countsByYear W27616099462023 @default.
• W2761609946 crossrefType "journal-article" @default.
• W2761609946 hasAuthorship W2761609946A5001257513 @default.
• W2761609946 hasAuthorship W2761609946A5008799011 @default.
• W2761609946 hasAuthorship W2761609946A5035670774 @default.
• W2761609946 hasAuthorship W2761609946A5071549667 @default.
• W2761609946 hasAuthorship W2761609946A5073860686 @default.
• W2761609946 hasAuthorship W2761609946A5074097572 @default.
• W2761609946 hasAuthorship W2761609946A5074358913 @default.
• W2761609946 hasAuthorship W2761609946A5078447184 @default.

• next