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• W2761738982 abstract "Benzodiazepines are psychoactive drugs and some of them also affect immune cells. We here characterized the inflammatory and infiltrating immune cells in the central nervous system (CNS) during the acute phase of experimental autoimmune encephalomyelitis (EAE) in animals treated with Diazepam. Also, we evaluated the expression of Translocator Protein (18 kDa) (TSPO), which is a biomarker of neuroinflammatory diseases. The results indicate that Diazepam exerts protective effects on EAE development, decreasing the incidence of the disease and reducing the number of inflammatory cells in CNS, with a concomitant decrease of TSPO levels in brain tissue and CNS inflammatory CD11b+ cells." @default.
• W2761738982 created "2017-10-20" @default.
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• W2761738982 date "2017-12-01" @default.
• W2761738982 modified "2023-10-06" @default.
• W2761738982 title "Diazepam treatment reduces inflammatory cells and mediators in the central nervous system of rats with experimental autoimmune encephalomyelitis" @default.
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• W2761738982 doi "https://doi.org/10.1016/j.jneuroim.2017.09.012" @default.
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