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• W2761739243 abstract "Combined 2-[18F]-fluoro-2-deoxy-d-glucose (FDG) positron-emission tomography (PET)/computed tomography (CT) has an established role in the staging of difficult cases of head and neck (HN) squamous cell carcinoma (SCC), looking for an unknown primary, assessing response post-chemotherapy at 3-6 months, and differentiating relapse from treatment effects in patients suspected to have tumour recurrence. The PET NECK trial, comparing PET/CT surveillance versus neck dissection in advanced head and neck cancer showed survival was similar among patients who underwent PET/CT-guided surveillance and those who underwent planned neck dissection, but surveillance was more cost-effective. There is growing interest in the use of hypoxia PET tracers, especially in targeting radiotherapy, where the radiotherapy dose can be boosted in regions of hypoxia; the use of 68Ga peptide tracers in neuroendocrine malignancy and also in the growing field of combined PET/magnetic resonance imaging (MRI). PET/MRI has the advantage of increased anatomical detail and radiation dose reduction combined with the molecular and metabolic data from PET, although PET/CT has the advantage in better sensitivity for imaging lung metastases. Thus far, there is good agreement between PET/CT and PET/MRI with high correlation between semi-quantitative measurements in primary, nodal, osseous, and soft-tissue lesions imaging. PET/MRI may indeed provide greater accuracy than the currently available imaging procedures in the staging and later treatment response evaluation in HNSCC." @default.
• W2761739243 created "2017-10-20" @default.
• W2761739243 creator A5027221531 @default.
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• W2761739243 date "2018-01-01" @default.
• W2761739243 modified "2023-09-30" @default.
• W2761739243 title "PET/CT and PET/MRI in head and neck malignancy" @default.
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• W2761739243 doi "https://doi.org/10.1016/j.crad.2017.09.001" @default.
• W2761739243 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29029767" @default.
• W2761739243 hasPublicationYear "2018" @default.
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