FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2761791519> ?p ?o ?g. }

• W2761791519 endingPage "362" @default.
• W2761791519 startingPage "357" @default.
• W2761791519 abstract "Vaginocervical stimulation (VCS) induces twice-daily prolactin (PRL) surges resulting in pseudopregnancy in the rat. Furthermore, activation of the extracellular signal-regulated kinase-1/2 (Erk-1/2) is involved in the effect of estradiol (E2) on the Prl gene expression in pituitary cells. Herein, we investigated whether Erk-1/2 signaling is involved in the control of Prl expression in the pituitary of VCS rats and whether VCS regulates the effect of E2 on Erk-1/2 and Prl in the pituitary. Estrous rats were assigned as control or VCS groups and 0, 6, 12 or 24h later the levels and localization of phosphorylated Erk-1/2 (p-Erk-1/2) were analyzed in the pituitary. The effect of an Erk-1/2 inhibitor PD98059 on the Prl level in the pituitary of control or VCS rats was also analyzed. Other control or VCS rats were treated with E2 and the level of p-Erk-1/2 and Prl were measured in the pituitary. In control rats, p-Erk-1/2 decreased at 6 and 12h and increased at 24h while Erk-1/2 was phosphorylated at all time points in VCS rats. p-Erk-1/2 was localized only in the anterior pituitary. PD98059 decreased Prl level in VCS, but not in control rats. Estradiol decreased Erk-1/2 phosphorylation although did not change Prl level in the pituitary of control or VCS rats. These findings show that prolonged activation of Erk-1/2 is necessary to induce Prl expression in the pituitary of VCS rats; however, VCS does not influence the role of E2 on the activation of Erk-1/2 and Prl expression the pituitary." @default.
• W2761791519 created "2017-10-20" @default.
• W2761791519 creator A5004911040 @default.
• W2761791519 creator A5012551284 @default.
• W2761791519 creator A5014647937 @default.
• W2761791519 creator A5021164177 @default.
• W2761791519 creator A5061400693 @default.
• W2761791519 creator A5080875270 @default.
• W2761791519 creator A5086269978 @default.
• W2761791519 date "2017-12-01" @default.
• W2761791519 modified "2023-10-06" @default.
• W2761791519 title "Prolactin gene expression in the pituitary of rats subjected to vaginocervical stimulation requires Erk-1/2 signaling" @default.
• W2761791519 cites W1564308550 @default.
• W2761791519 cites W1792395986 @default.
• W2761791519 cites W1965225612 @default.
• W2761791519 cites W1971334610 @default.
• W2761791519 cites W1972552989 @default.
• W2761791519 cites W1981739548 @default.
• W2761791519 cites W1986703210 @default.
• W2761791519 cites W1991727531 @default.
• W2761791519 cites W1996287714 @default.
• W2761791519 cites W2035560626 @default.
• W2761791519 cites W2041819796 @default.
• W2761791519 cites W2046034361 @default.
• W2761791519 cites W2057313063 @default.
• W2761791519 cites W2069281153 @default.
• W2761791519 cites W2071103990 @default.
• W2761791519 cites W2072462502 @default.
• W2761791519 cites W2087611379 @default.
• W2761791519 cites W2099666698 @default.
• W2761791519 cites W2101178259 @default.
• W2761791519 cites W2102988906 @default.
• W2761791519 cites W2103341871 @default.
• W2761791519 cites W2104954205 @default.
• W2761791519 cites W2106877352 @default.
• W2761791519 cites W2107277218 @default.
• W2761791519 cites W2110918147 @default.
• W2761791519 cites W2115070926 @default.
• W2761791519 cites W2118155458 @default.
• W2761791519 cites W2119425653 @default.
• W2761791519 cites W2138835179 @default.
• W2761791519 cites W2140085338 @default.
• W2761791519 cites W2140861378 @default.
• W2761791519 cites W2146829563 @default.
• W2761791519 cites W2154808997 @default.
• W2761791519 cites W2158320945 @default.
• W2761791519 cites W2264534620 @default.
• W2761791519 cites W2298997906 @default.
• W2761791519 doi "https://doi.org/10.1016/j.repbio.2017.10.001" @default.
• W2761791519 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29030125" @default.
• W2761791519 hasPublicationYear "2017" @default.
• W2761791519 type Work @default.
• W2761791519 sameAs 2761791519 @default.
• W2761791519 citedByCount "1" @default.
• W2761791519 countsByYear W27617915192020 @default.
• W2761791519 crossrefType "journal-article" @default.
• W2761791519 hasAuthorship W2761791519A5004911040 @default.
• W2761791519 hasAuthorship W2761791519A5012551284 @default.
• W2761791519 hasAuthorship W2761791519A5014647937 @default.
• W2761791519 hasAuthorship W2761791519A5021164177 @default.
• W2761791519 hasAuthorship W2761791519A5061400693 @default.
• W2761791519 hasAuthorship W2761791519A5080875270 @default.
• W2761791519 hasAuthorship W2761791519A5086269978 @default.
• W2761791519 hasConcept C11960822 @default.
• W2761791519 hasConcept C126322002 @default.
• W2761791519 hasConcept C134018914 @default.
• W2761791519 hasConcept C184235292 @default.
• W2761791519 hasConcept C185592680 @default.
• W2761791519 hasConcept C24998067 @default.
• W2761791519 hasConcept C2779029589 @default.
• W2761791519 hasConcept C2779064019 @default.
• W2761791519 hasConcept C55493867 @default.
• W2761791519 hasConcept C57074206 @default.
• W2761791519 hasConcept C71315377 @default.
• W2761791519 hasConcept C71924100 @default.
• W2761791519 hasConcept C86803240 @default.
• W2761791519 hasConceptScore W2761791519C11960822 @default.
• W2761791519 hasConceptScore W2761791519C126322002 @default.
• W2761791519 hasConceptScore W2761791519C134018914 @default.
• W2761791519 hasConceptScore W2761791519C184235292 @default.
• W2761791519 hasConceptScore W2761791519C185592680 @default.
• W2761791519 hasConceptScore W2761791519C24998067 @default.
• W2761791519 hasConceptScore W2761791519C2779029589 @default.
• W2761791519 hasConceptScore W2761791519C2779064019 @default.
• W2761791519 hasConceptScore W2761791519C55493867 @default.
• W2761791519 hasConceptScore W2761791519C57074206 @default.
• W2761791519 hasConceptScore W2761791519C71315377 @default.
• W2761791519 hasConceptScore W2761791519C71924100 @default.
• W2761791519 hasConceptScore W2761791519C86803240 @default.
• W2761791519 hasIssue "4" @default.
• W2761791519 hasLocation W27617915191 @default.
• W2761791519 hasLocation W27617915192 @default.
• W2761791519 hasOpenAccess W2761791519 @default.
• W2761791519 hasPrimaryLocation W27617915191 @default.
• W2761791519 hasRelatedWork W1966296538 @default.
• W2761791519 hasRelatedWork W2000124881 @default.
• W2761791519 hasRelatedWork W2033209790 @default.
• W2761791519 hasRelatedWork W2050420293 @default.

• next