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- W2762024920 abstract "Introduction: Hemophagocytic lymphohistiocytosis (HLH) is an aggressive inflammatory disease characterized by excessive activity of histiocytes and lymphocytes that is well established in pediatrics, but is under recognized in adults. According to the HLH-2004 pediatric guidelines, five of the following eight criteria must be met to diagnose HLH: fever >38.5° C, splenomegaly; cytopenias affecting ≥ two cell lines; hypertriglyceridemia or hypofibrinogenemia; evidence of hemophagocytosis in the bone marrow, spleen or lymph nodes; hyperferritinemia; low NK cell activity; or high levels of soluble CD25. Once a diagnosis of HLH is established, investigations …" @default.
- W2762024920 created "2017-10-20" @default.
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- W2762024920 date "2017-01-01" @default.
- W2762024920 modified "2023-09-26" @default.
- W2762024920 title "Widening the Differential: a Case of Hemophagocytic Lymphohistiocytosis Disguised as a Fever of Unknown Origin" @default.
- W2762024920 doi "https://doi.org/10.1542/peds.142.1_meetingabstract.705" @default.
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