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- W2762061041 abstract "Abstract The regulation of circadian gene expression remains largely unknown in farmed fish larvae. In this study, a high-density oligonucleotide microarray was used to examine the daily expression of 13,939 unique genes in whole gilthead sea bream ( Sparus aurata ) larvae with fast growth potentiality. Up to 2,229 genes were differentially expressed, and the first two components of Principal Component Analysis explained more than 81% of the total variance. Clustering analysis of differentially expressed genes identified 4 major clusters that were triggered sequentially, with a maximum expression at 0 h, 3 h, 9–15 h and 18-21 h zeitgeber time. Various core clock genes ( per1, per2 , per 3 , bmal1, cry1, cry 2 , clock ) were identified in clusters 1–3, and their expression was significantly correlated with several genes in each cluster. Functional analysis revealed a daily consecutive activation of canonical pathways related to phototransduction, intermediary metabolism, development, chromatin remodeling, and cell cycle regulation. This daily transcriptome of whole larvae resembles a cell cycle (G1/S, G2/M, and M/G1 transitions) in synchronization with multicellular processes, such as neuromuscular development. This study supports that the actively feeding fish larval transcriptome is temporally organized in a 24-h cycle, likely for maximizing growth and development." @default.
- W2762061041 created "2017-10-20" @default.
- W2762061041 creator A5007459215 @default.
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- W2762061041 date "2017-10-11" @default.
- W2762061041 modified "2023-10-18" @default.
- W2762061041 title "The circadian transcriptome of marine fish (Sparus aurata) larvae reveals highly synchronized biological processes at the whole organism level" @default.
- W2762061041 cites W1500458256 @default.
- W2762061041 cites W1509591029 @default.
- W2762061041 cites W1544564404 @default.
- W2762061041 cites W1548090883 @default.
- W2762061041 cites W1565313690 @default.
- W2762061041 cites W1574825142 @default.
- W2762061041 cites W1657470660 @default.
- W2762061041 cites W1778457861 @default.
- W2762061041 cites W1975447993 @default.
- W2762061041 cites W1981948323 @default.
- W2762061041 cites W1983510823 @default.
- W2762061041 cites W1984009846 @default.
- W2762061041 cites W1987433986 @default.
- W2762061041 cites W1988394059 @default.
- W2762061041 cites W1989697315 @default.
- W2762061041 cites W1990264305 @default.
- W2762061041 cites W1991199800 @default.
- W2762061041 cites W1992206554 @default.
- W2762061041 cites W1993496273 @default.
- W2762061041 cites W1994960533 @default.
- W2762061041 cites W1997179110 @default.
- W2762061041 cites W1998585946 @default.
- W2762061041 cites W2000314545 @default.
- W2762061041 cites W2002511568 @default.
- W2762061041 cites W2012053950 @default.
- W2762061041 cites W2014601896 @default.
- W2762061041 cites W2014928029 @default.
- W2762061041 cites W2016016539 @default.
- W2762061041 cites W2023690137 @default.
- W2762061041 cites W2027976634 @default.
- W2762061041 cites W2030496040 @default.
- W2762061041 cites W2033231351 @default.
- W2762061041 cites W2034130381 @default.
- W2762061041 cites W2037684948 @default.
- W2762061041 cites W2043869660 @default.
- W2762061041 cites W2052863273 @default.
- W2762061041 cites W2053866174 @default.
- W2762061041 cites W2054816184 @default.
- W2762061041 cites W2057162008 @default.
- W2762061041 cites W2061769555 @default.
- W2762061041 cites W2063552088 @default.
- W2762061041 cites W2063946784 @default.
- W2762061041 cites W2067885554 @default.
- W2762061041 cites W2081296105 @default.
- W2762061041 cites W2085103039 @default.
- W2762061041 cites W2088032711 @default.
- W2762061041 cites W2089749987 @default.
- W2762061041 cites W2091108188 @default.
- W2762061041 cites W2093505571 @default.
- W2762061041 cites W2094103203 @default.
- W2762061041 cites W2100472329 @default.
- W2762061041 cites W2102246475 @default.
- W2762061041 cites W2102335465 @default.
- W2762061041 cites W2107277218 @default.
- W2762061041 cites W2114205900 @default.
- W2762061041 cites W2119284644 @default.
- W2762061041 cites W2123584715 @default.
- W2762061041 cites W2128564208 @default.
- W2762061041 cites W2134569794 @default.
- W2762061041 cites W2135364184 @default.
- W2762061041 cites W2136818107 @default.
- W2762061041 cites W2137991275 @default.
- W2762061041 cites W2138747472 @default.
- W2762061041 cites W2142352545 @default.
- W2762061041 cites W2145556476 @default.
- W2762061041 cites W2162245562 @default.
- W2762061041 cites W2164824098 @default.
- W2762061041 cites W2165213376 @default.
- W2762061041 cites W2169326906 @default.
- W2762061041 cites W2172252517 @default.
- W2762061041 cites W2172401944 @default.
- W2762061041 cites W2176808813 @default.
- W2762061041 cites W2192080449 @default.
- W2762061041 cites W2257086668 @default.
- W2762061041 cites W2280053545 @default.
- W2762061041 cites W2412942271 @default.
- W2762061041 cites W2437349461 @default.
- W2762061041 cites W2467573270 @default.
- W2762061041 cites W2471154851 @default.
- W2762061041 cites W2482110097 @default.
- W2762061041 cites W2575556187 @default.
- W2762061041 cites W2593993726 @default.
- W2762061041 doi "https://doi.org/10.1038/s41598-017-13514-w" @default.
- W2762061041 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5636797" @default.
- W2762061041 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29021622" @default.
- W2762061041 hasPublicationYear "2017" @default.
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