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- W2762584347 abstract "Tissue regeneration following acute or persistent inflammation can manifest a spectrum of phenotypes ranging from the adaptive to the pathologic. Heterotopic Ossification (HO), the endochondral formation of bone within soft-tissue structures following severe injury serves as a prominent example of pathologic differentiation; and remains a persistent clinical issue incurring significant patient morbidity and expense to adequately diagnose and treat. The pathogenesis of HO provides an intriguing opportunity to better characterize the cellular and cell-signaling contributors to aberrant differentiation. Indeed, recent work has continued to resolve the unique cellular lineages, and causative pathways responsible for ectopic bone development yielding promising avenues for the development of novel therapeutic strategies shown to be successful in analogous animal models of HO development. This review details advances in the understanding of HO in the context of inciting inflammation, and explains how these advances inform the current standards of diagnosis and treatment." @default.
- W2762584347 created "2017-10-20" @default.
- W2762584347 creator A5013155693 @default.
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- W2762584347 creator A5085393130 @default.
- W2762584347 creator A5086692185 @default.
- W2762584347 date "2018-04-01" @default.
- W2762584347 modified "2023-10-17" @default.
- W2762584347 title "Heterotopic ossification and the elucidation of pathologic differentiation" @default.
- W2762584347 cites W109258032 @default.
- W2762584347 cites W1513906254 @default.
- W2762584347 cites W1517472002 @default.
- W2762584347 cites W1555097282 @default.
- W2762584347 cites W170696449 @default.
- W2762584347 cites W1854064841 @default.
- W2762584347 cites W1908563203 @default.
- W2762584347 cites W1964011144 @default.
- W2762584347 cites W1964474592 @default.
- W2762584347 cites W1968493594 @default.
- W2762584347 cites W1972429412 @default.
- W2762584347 cites W1976084770 @default.
- W2762584347 cites W1979412100 @default.
- W2762584347 cites W1979666470 @default.
- W2762584347 cites W1981514775 @default.
- W2762584347 cites W1984746738 @default.
- W2762584347 cites W1985855700 @default.
- W2762584347 cites W1985876414 @default.
- W2762584347 cites W1990630756 @default.
- W2762584347 cites W1995031048 @default.
- W2762584347 cites W1997604272 @default.
- W2762584347 cites W2000372495 @default.
- W2762584347 cites W2000403994 @default.
- W2762584347 cites W2002179012 @default.
- W2762584347 cites W2006854630 @default.
- W2762584347 cites W2010253303 @default.
- W2762584347 cites W2012836529 @default.
- W2762584347 cites W2012886552 @default.
- W2762584347 cites W2017343965 @default.
- W2762584347 cites W2029089179 @default.
- W2762584347 cites W2030381058 @default.
- W2762584347 cites W2032085255 @default.
- W2762584347 cites W2037716466 @default.
- W2762584347 cites W2039308576 @default.
- W2762584347 cites W2049928766 @default.
- W2762584347 cites W2052590294 @default.
- W2762584347 cites W2053312128 @default.
- W2762584347 cites W2059332035 @default.
- W2762584347 cites W2059460453 @default.
- W2762584347 cites W2059546701 @default.
- W2762584347 cites W2063445980 @default.
- W2762584347 cites W2063730843 @default.
- W2762584347 cites W2065705414 @default.
- W2762584347 cites W2065885294 @default.
- W2762584347 cites W2066365496 @default.
- W2762584347 cites W2068818864 @default.
- W2762584347 cites W2070696494 @default.
- W2762584347 cites W2073551037 @default.
- W2762584347 cites W2074230216 @default.
- W2762584347 cites W2075727016 @default.
- W2762584347 cites W2078691010 @default.
- W2762584347 cites W2083252994 @default.
- W2762584347 cites W2086202498 @default.
- W2762584347 cites W2087836177 @default.
- W2762584347 cites W2099003301 @default.
- W2762584347 cites W2100417606 @default.
- W2762584347 cites W2107503723 @default.
- W2762584347 cites W2110032258 @default.
- W2762584347 cites W2110485236 @default.
- W2762584347 cites W2112830164 @default.
- W2762584347 cites W2113679184 @default.
- W2762584347 cites W2120389451 @default.
- W2762584347 cites W2123126591 @default.
- W2762584347 cites W2123641963 @default.
- W2762584347 cites W2124048161 @default.
- W2762584347 cites W2124962116 @default.
- W2762584347 cites W2125987139 @default.
- W2762584347 cites W2128603782 @default.
- W2762584347 cites W2134819599 @default.
- W2762584347 cites W2135046649 @default.
- W2762584347 cites W2137915344 @default.
- W2762584347 cites W2138177802 @default.
- W2762584347 cites W2139561575 @default.
- W2762584347 cites W2141628875 @default.
- W2762584347 cites W2144578935 @default.
- W2762584347 cites W2145304853 @default.
- W2762584347 cites W2151418643 @default.
- W2762584347 cites W2154767933 @default.
- W2762584347 cites W2157372796 @default.
- W2762584347 cites W2158048826 @default.
- W2762584347 cites W2161908205 @default.
- W2762584347 cites W2164094296 @default.
- W2762584347 cites W2164703635 @default.
- W2762584347 cites W2169474931 @default.
- W2762584347 cites W2171133614 @default.