Matches in SemOpenAlex for { <https://semopenalex.org/work/W2762881569> ?p ?o ?g. }
- W2762881569 endingPage "142" @default.
- W2762881569 startingPage "134" @default.
- W2762881569 abstract "Direct and selective terminal oxidation of medium-chain n-alkanes is a major challenge in chemistry. Efforts to achieve this have so far resulted in low specificity and overoxidized products. Biocatalytic oxidation of medium-chain n-alkanes – with for example the alkane monooxygenase AlkB from P. putida GPo1- on the other hand is highly selective. However, it also results in overoxidation. Moreover, diterminal oxidation of medium-chain n-alkanes is inefficient. Hence, α,ω-bifunctional monomers are mostly produced from olefins using energy intensive, multi-step processes. By combining biocatalytic oxidation with esterification we drastically increased diterminal oxidation upto 92 mol% and reduced overoxidation to 3% for n-hexane. This methodology allowed us to convert medium-chain n-alkanes into α,ω-diacetoxyalkanes and esterified α,ω-dicarboxylic acids. We achieved this in a one-pot reaction with resting-cell suspensions of genetically engineered Escherichia coli. The combination of terminal oxidation and esterification constitutes a versatile toolbox to produce α,ω-bifunctional monomers from n-alkanes." @default.
- W2762881569 created "2017-10-20" @default.
- W2762881569 creator A5006100277 @default.
- W2762881569 creator A5006947941 @default.
- W2762881569 creator A5037182888 @default.
- W2762881569 creator A5041944372 @default.
- W2762881569 creator A5080008667 @default.
- W2762881569 date "2017-11-01" @default.
- W2762881569 modified "2023-09-25" @default.
- W2762881569 title "Biocatalytic, one-pot diterminal oxidation and esterification of n-alkanes for production of α,ω-diol and α,ω-dicarboxylic acid esters" @default.
- W2762881569 cites W1493556845 @default.
- W2762881569 cites W1515260688 @default.
- W2762881569 cites W1761632173 @default.
- W2762881569 cites W1967600412 @default.
- W2762881569 cites W1970896739 @default.
- W2762881569 cites W1977722568 @default.
- W2762881569 cites W2000485935 @default.
- W2762881569 cites W2000749087 @default.
- W2762881569 cites W2026559278 @default.
- W2762881569 cites W2037530927 @default.
- W2762881569 cites W2041147269 @default.
- W2762881569 cites W2044814686 @default.
- W2762881569 cites W2044894294 @default.
- W2762881569 cites W2047195899 @default.
- W2762881569 cites W2050107614 @default.
- W2762881569 cites W2055242720 @default.
- W2762881569 cites W2060674069 @default.
- W2762881569 cites W2065403136 @default.
- W2762881569 cites W2073499207 @default.
- W2762881569 cites W2074893062 @default.
- W2762881569 cites W2079025800 @default.
- W2762881569 cites W2081121707 @default.
- W2762881569 cites W2085747199 @default.
- W2762881569 cites W2091819558 @default.
- W2762881569 cites W2097875863 @default.
- W2762881569 cites W2100582786 @default.
- W2762881569 cites W2117560339 @default.
- W2762881569 cites W2128804683 @default.
- W2762881569 cites W2130669856 @default.
- W2762881569 cites W2145723041 @default.
- W2762881569 cites W2148331201 @default.
- W2762881569 cites W2158479639 @default.
- W2762881569 cites W2163727020 @default.
- W2762881569 cites W2298109506 @default.
- W2762881569 cites W2336209448 @default.
- W2762881569 cites W2341848362 @default.
- W2762881569 cites W2344431831 @default.
- W2762881569 cites W2384114645 @default.
- W2762881569 cites W2601224882 @default.
- W2762881569 cites W2750357512 @default.
- W2762881569 cites W2777651827 @default.
- W2762881569 cites W2949285876 @default.
- W2762881569 cites W2598707300 @default.
- W2762881569 doi "https://doi.org/10.1016/j.ymben.2017.10.005" @default.
- W2762881569 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28993212" @default.
- W2762881569 hasPublicationYear "2017" @default.
- W2762881569 type Work @default.
- W2762881569 sameAs 2762881569 @default.
- W2762881569 citedByCount "13" @default.
- W2762881569 countsByYear W27628815692018 @default.
- W2762881569 countsByYear W27628815692019 @default.
- W2762881569 countsByYear W27628815692020 @default.
- W2762881569 countsByYear W27628815692021 @default.
- W2762881569 countsByYear W27628815692022 @default.
- W2762881569 countsByYear W27628815692023 @default.
- W2762881569 crossrefType "journal-article" @default.
- W2762881569 hasAuthorship W2762881569A5006100277 @default.
- W2762881569 hasAuthorship W2762881569A5006947941 @default.
- W2762881569 hasAuthorship W2762881569A5037182888 @default.
- W2762881569 hasAuthorship W2762881569A5041944372 @default.
- W2762881569 hasAuthorship W2762881569A5080008667 @default.
- W2762881569 hasConcept C161790260 @default.
- W2762881569 hasConcept C166940927 @default.
- W2762881569 hasConcept C178790620 @default.
- W2762881569 hasConcept C181199279 @default.
- W2762881569 hasConcept C185592680 @default.
- W2762881569 hasConcept C21951064 @default.
- W2762881569 hasConcept C2777207669 @default.
- W2762881569 hasConcept C2780443040 @default.
- W2762881569 hasConcept C2780543182 @default.
- W2762881569 hasConcept C2781327020 @default.
- W2762881569 hasConcept C521977710 @default.
- W2762881569 hasConceptScore W2762881569C161790260 @default.
- W2762881569 hasConceptScore W2762881569C166940927 @default.
- W2762881569 hasConceptScore W2762881569C178790620 @default.
- W2762881569 hasConceptScore W2762881569C181199279 @default.
- W2762881569 hasConceptScore W2762881569C185592680 @default.
- W2762881569 hasConceptScore W2762881569C21951064 @default.
- W2762881569 hasConceptScore W2762881569C2777207669 @default.
- W2762881569 hasConceptScore W2762881569C2780443040 @default.
- W2762881569 hasConceptScore W2762881569C2780543182 @default.
- W2762881569 hasConceptScore W2762881569C2781327020 @default.
- W2762881569 hasConceptScore W2762881569C521977710 @default.
- W2762881569 hasLocation W27628815691 @default.
- W2762881569 hasLocation W27628815692 @default.
- W2762881569 hasOpenAccess W2762881569 @default.
- W2762881569 hasPrimaryLocation W27628815691 @default.
- W2762881569 hasRelatedWork W2065583757 @default.