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• W2762983275 abstract "The introduction of vaccine technology has facilitated an unprecedented multiantigen approach to develop an effective vaccine against complex pathogens, such as Plasmodium spp., that cause severe malaria. The capacity of multisubunit DNA vaccines encoding different stage Plasmodium antigens to induce CD8(+) cytotoxic T lymphocytes and IFN-gamma responses in mice, monkeys and humans has been observed. Moreover, genetic vaccination may be multi-immune (i.e., capable of eliciting more than one type of immune response, including cell-mediated and humoral). In the case of malaria parasites, a cytotoxic T-lymphocyte response is categorically needed against the intracellular hepatocyte stage while a humoral response, with antibodies targeted against antigens from all stages of the life cycle, is also needed. Therefore, the key to success for any DNA-based therapy is to design a vector able to serve as a safe and efficient delivery system. This has encouraged the development of nonviral DNA-mediated gene-transfer techniques, such as liposomes, virosomes, microspheres and nanoparticles. Efficient and relatively safe DNA transfection using lipoplexes makes them an appealing alternative to be explored for gene delivery. In addition, liposome-entrapped DNA has been shown to enhance the potency of DNA vaccines, possibly by facilitating uptake of the plasmid by antigen-presenting cells. Another recent technology using cationic lipids has been deployed and has generated substantial interest in this approach to gene transfer. This review comprises various aspects that could be decisive in the formulation of efficient and stable carrier system(s) for the development of malaria vaccines." @default.
• W2762983275 created "2017-10-20" @default.
• W2762983275 creator A5030635639 @default.
• W2762983275 creator A5047074503 @default.
• W2762983275 creator A5054591902 @default.
• W2762983275 creator A5060483993 @default.
• W2762983275 date "2008-05-01" @default.
• W2762983275 modified "2023-09-23" @default.
• W2762983275 title "Various carrier system(s)- mediated genetic vaccination strategies against malaria - Retracted" @default.
• W2762983275 cites W100984399 @default.
• W2762983275 cites W1530964560 @default.
• W2762983275 cites W1537342340 @default.
• W2762983275 cites W1564610477 @default.
• W2762983275 cites W1580639099 @default.
• W2762983275 cites W1601065475 @default.
• W2762983275 cites W1714533781 @default.
• W2762983275 cites W1750791497 @default.
• W2762983275 cites W1799419298 @default.
• W2762983275 cites W1824624834 @default.
• W2762983275 cites W1928902541 @default.
• W2762983275 cites W1966284404 @default.
• W2762983275 cites W1966914670 @default.
• W2762983275 cites W1968232819 @default.
• W2762983275 cites W1969251343 @default.
• W2762983275 cites W1969990097 @default.
• W2762983275 cites W1970999371 @default.
• W2762983275 cites W1971208013 @default.
• W2762983275 cites W1973827427 @default.
• W2762983275 cites W1974629753 @default.
• W2762983275 cites W1979707388 @default.
• W2762983275 cites W1980883845 @default.
• W2762983275 cites W1985544838 @default.
• W2762983275 cites W1997659501 @default.
• W2762983275 cites W1999280625 @default.
• W2762983275 cites W1999298446 @default.
• W2762983275 cites W2002100103 @default.
• W2762983275 cites W2003818151 @default.
• W2762983275 cites W2004554125 @default.
• W2762983275 cites W2005826917 @default.
• W2762983275 cites W2007098121 @default.
• W2762983275 cites W2010507557 @default.
• W2762983275 cites W2018969311 @default.
• W2762983275 cites W2023242366 @default.
• W2762983275 cites W2023871112 @default.
• W2762983275 cites W2025326880 @default.
• W2762983275 cites W2029626795 @default.
• W2762983275 cites W2030011507 @default.
• W2762983275 cites W2030261331 @default.
• W2762983275 cites W2030672230 @default.
• W2762983275 cites W2032247822 @default.
• W2762983275 cites W2032314051 @default.
• W2762983275 cites W2036106138 @default.
• W2762983275 cites W2036227121 @default.
• W2762983275 cites W2037905762 @default.
• W2762983275 cites W2039179861 @default.
• W2762983275 cites W2039481952 @default.
• W2762983275 cites W2045026198 @default.
• W2762983275 cites W2047834274 @default.
• W2762983275 cites W2051642719 @default.
• W2762983275 cites W2051809585 @default.
• W2762983275 cites W2053801470 @default.
• W2762983275 cites W2056401826 @default.
• W2762983275 cites W2056624347 @default.
• W2762983275 cites W2057572412 @default.
• W2762983275 cites W2058162103 @default.
• W2762983275 cites W2058416686 @default.
• W2762983275 cites W2058848793 @default.
• W2762983275 cites W2064565302 @default.
• W2762983275 cites W2066799804 @default.
• W2762983275 cites W2067559517 @default.
• W2762983275 cites W2069038428 @default.
• W2762983275 cites W2069410547 @default.
• W2762983275 cites W2071718034 @default.
• W2762983275 cites W2074526587 @default.
• W2762983275 cites W2075817888 @default.
• W2762983275 cites W2080794749 @default.
• W2762983275 cites W2083699731 @default.
• W2762983275 cites W2084381085 @default.
• W2762983275 cites W2085255220 @default.
• W2762983275 cites W2086004205 @default.
• W2762983275 cites W2087392665 @default.
• W2762983275 cites W2087667054 @default.
• W2762983275 cites W2088582527 @default.
• W2762983275 cites W2089901811 @default.
• W2762983275 cites W2090698640 @default.
• W2762983275 cites W2093017893 @default.
• W2762983275 cites W2095453347 @default.
• W2762983275 cites W2097169724 @default.
• W2762983275 cites W2098795075 @default.
• W2762983275 cites W2099086982 @default.
• W2762983275 cites W2099244599 @default.
• W2762983275 cites W2102057936 @default.
• W2762983275 cites W2102283103 @default.
• W2762983275 cites W2104936846 @default.
• W2762983275 cites W2105852605 @default.
• W2762983275 cites W2105920586 @default.
• W2762983275 cites W2106891922 @default.
• W2762983275 cites W2108257302 @default.

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