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• W2762992647 abstract "A new furanone derivative, butanolide A (1), and a new sesquiterpene, guignarderemophilane F (2), together with six known compounds, were isolated from the fungus Penicillium sp. S-1-18 derived from Antarctic marine. The new structures were determined by spectroscopic studies such as 1D- and 2D-NMR and MS analyses. The absolute configuration of 1 was determined by the modified Mosher’s method, while the absolute configuration of 2 was determined by calculated ECD spectroscopy. The isolated secondary metabolites were evaluated for their protein tyrosine phosphatase 1B (PTP1B) inhibitory activity. Compound 1 showed moderate inhibitory activity against PTP1B with IC50 value of 27.4 μM." @default.
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• W2762992647 date "2017-10-09" @default.
• W2762992647 modified "2023-09-27" @default.
• W2762992647 title "Furanone derivative and sesquiterpene from Antarctic marine-derived fungus <i>Penicillium</i> sp. S-1-18" @default.
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• W2762992647 doi "https://doi.org/10.1080/10286020.2017.1385604" @default.
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