FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2763503213> ?p ?o ?g. }

• W2763503213 endingPage "1691" @default.
• W2763503213 startingPage "1683" @default.
• W2763503213 abstract "The aim of present attempt deals with preparation of binary dispersion of sericin, waste of sericulture industry in order to enhance solubility and dissolution of poorly soluble drugs. Solid dispersions (SDs) of BCS-II drugs were prepared by spray drying, solvent evaporation, ball milling and physical mixing in ratio of drug:sericin (1:0.5, 1:1, 1:1.5, 1:2, 1:2.5 and 1:3). Further, SDs were investigated by solubility, ATR-FTIR, XRD, DSC, micromeritics and tablettability, surface morphology and in-vitro dissolution. Results demonstrated that, sericin improves solubility of drugs by 8-10 fold. The ATR-FTIR showed the slight shifting/broadening of principle peaks corresponding to NH and OH. Spray dried (1:2w/w) SDs showed maximum reduction in crystallinity of drugs indicating drug was molecularly distributed and was in amorphous state. Spray dried SDs of meloxicam showed better compressibility and compactibility. The microphotograph of spray dried SDs of lornoxicam and meloxicam showed bowl shaped and blend of bowl and spherical particles respectively, while spray dried SDs of felodepine showed spherical shape. The spray dried SDs (1:2w/w) displayed better dissolution performance than other methods Conclusively, sericin offers a hydrophilic matrix to deliver poor water soluble drugs and its aerodynamic shape may show a great potential for various drug deliveries." @default.
• W2763503213 created "2017-10-20" @default.
• W2763503213 creator A5003228032 @default.
• W2763503213 creator A5046179059 @default.
• W2763503213 creator A5080807575 @default.
• W2763503213 creator A5082698646 @default.
• W2763503213 date "2018-02-01" @default.
• W2763503213 modified "2023-09-26" @default.
• W2763503213 title "Screening of drug-sericin solid dispersions for improved solubility and dissolution" @default.
• W2763503213 cites W1972974331 @default.
• W2763503213 cites W1976868949 @default.
• W2763503213 cites W1998089412 @default.
• W2763503213 cites W1999893943 @default.
• W2763503213 cites W2011182207 @default.
• W2763503213 cites W2011354686 @default.
• W2763503213 cites W2020068592 @default.
• W2763503213 cites W2022787080 @default.
• W2763503213 cites W2025607183 @default.
• W2763503213 cites W2031450493 @default.
• W2763503213 cites W2039104539 @default.
• W2763503213 cites W2051032213 @default.
• W2763503213 cites W2053153816 @default.
• W2763503213 cites W2055400540 @default.
• W2763503213 cites W2059454854 @default.
• W2763503213 cites W2059602593 @default.
• W2763503213 cites W2065279002 @default.
• W2763503213 cites W2071060910 @default.
• W2763503213 cites W2076292647 @default.
• W2763503213 cites W2080411925 @default.
• W2763503213 cites W2090771033 @default.
• W2763503213 cites W2138007197 @default.
• W2763503213 cites W2151132896 @default.
• W2763503213 cites W2161961055 @default.
• W2763503213 cites W2168300796 @default.
• W2763503213 cites W2358125182 @default.
• W2763503213 cites W2395128162 @default.
• W2763503213 cites W2596492315 @default.
• W2763503213 doi "https://doi.org/10.1016/j.ijbiomac.2017.10.035" @default.
• W2763503213 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29030184" @default.
• W2763503213 hasPublicationYear "2018" @default.
• W2763503213 type Work @default.
• W2763503213 sameAs 2763503213 @default.
• W2763503213 citedByCount "15" @default.
• W2763503213 countsByYear W27635032132018 @default.
• W2763503213 countsByYear W27635032132019 @default.
• W2763503213 countsByYear W27635032132020 @default.
• W2763503213 countsByYear W27635032132021 @default.
• W2763503213 countsByYear W27635032132022 @default.
• W2763503213 countsByYear W27635032132023 @default.
• W2763503213 crossrefType "journal-article" @default.
• W2763503213 hasAuthorship W2763503213A5003228032 @default.
• W2763503213 hasAuthorship W2763503213A5046179059 @default.
• W2763503213 hasAuthorship W2763503213A5080807575 @default.
• W2763503213 hasAuthorship W2763503213A5082698646 @default.
• W2763503213 hasConcept C127413603 @default.
• W2763503213 hasConcept C13965031 @default.
• W2763503213 hasConcept C155574463 @default.
• W2763503213 hasConcept C159985019 @default.
• W2763503213 hasConcept C160892712 @default.
• W2763503213 hasConcept C178790620 @default.
• W2763503213 hasConcept C185592680 @default.
• W2763503213 hasConcept C191168616 @default.
• W2763503213 hasConcept C192562407 @default.
• W2763503213 hasConcept C206767735 @default.
• W2763503213 hasConcept C2776035855 @default.
• W2763503213 hasConcept C2779587474 @default.
• W2763503213 hasConcept C2780431358 @default.
• W2763503213 hasConcept C42360764 @default.
• W2763503213 hasConcept C43617362 @default.
• W2763503213 hasConcept C46275449 @default.
• W2763503213 hasConcept C521977710 @default.
• W2763503213 hasConcept C8010536 @default.
• W2763503213 hasConcept C88380143 @default.
• W2763503213 hasConceptScore W2763503213C127413603 @default.
• W2763503213 hasConceptScore W2763503213C13965031 @default.
• W2763503213 hasConceptScore W2763503213C155574463 @default.
• W2763503213 hasConceptScore W2763503213C159985019 @default.
• W2763503213 hasConceptScore W2763503213C160892712 @default.
• W2763503213 hasConceptScore W2763503213C178790620 @default.
• W2763503213 hasConceptScore W2763503213C185592680 @default.
• W2763503213 hasConceptScore W2763503213C191168616 @default.
• W2763503213 hasConceptScore W2763503213C192562407 @default.
• W2763503213 hasConceptScore W2763503213C206767735 @default.
• W2763503213 hasConceptScore W2763503213C2776035855 @default.
• W2763503213 hasConceptScore W2763503213C2779587474 @default.
• W2763503213 hasConceptScore W2763503213C2780431358 @default.
• W2763503213 hasConceptScore W2763503213C42360764 @default.
• W2763503213 hasConceptScore W2763503213C43617362 @default.
• W2763503213 hasConceptScore W2763503213C46275449 @default.
• W2763503213 hasConceptScore W2763503213C521977710 @default.
• W2763503213 hasConceptScore W2763503213C8010536 @default.
• W2763503213 hasConceptScore W2763503213C88380143 @default.
• W2763503213 hasFunder F4320320721 @default.
• W2763503213 hasFunder F4320323579 @default.
• W2763503213 hasLocation W27635032131 @default.
• W2763503213 hasLocation W27635032132 @default.
• W2763503213 hasOpenAccess W2763503213 @default.
• W2763503213 hasPrimaryLocation W27635032131 @default.

• next