FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2763694566> ?p ?o ?g. }

• W2763694566 endingPage "100763" @default.
• W2763694566 startingPage "100754" @default.
• W2763694566 abstract "Pulmonary large cell carcinoma (LCC) was re-defined under the 2015 WHO classification criteria. However, the clinicopathological features and genetic mutation statuses of Chinese LCC patients based on the new classification have rarely been investigated. Twenty-four Chinese surgically resected LCC patients previously diagnosed under the 2004 WHO criteria were re-classified under the 2015 WHO criteria. Genetic analysis was performed using next-generation sequencing of 46 cancer-related genes. The correlation of clinicopathological and genetic data was further analyzed. Eight patients were re-defined as LCCs, and 16 patients were defined as non-LCCs under the refined criteria. All LCC patients were male, and 7 patients were smokers. No significant differences in age, gender, smoking status, primary site, TNM staging and overall survival were observed between the LCC and non-LCC patients under the refined criteria. Four of the 8 LCC patients presented TP53 mutations, and no somatic mutations were detected in the other 4 LCCs under the refined criteria. For the 16 non-LCCs, not only TP53 and KRAS but also EGFR, KIT, PIK3CA, PTEN, IDH1, APC, ATM and BRAF mutations were also observed. In addition, LCCs without TP53 mutations did not present any gene mutations under the 2004 or 2015 WHO criteria. Importantly, the patients with TP53 mutation exhibited a trend with a worse survival outcome at the time of follow-up. The new WHO diagnosis criteria have superior performance in precise molecular classification for LCC patients." @default.
• W2763694566 created "2017-10-20" @default.
• W2763694566 creator A5020160235 @default.
• W2763694566 creator A5029297164 @default.
• W2763694566 creator A5035705128 @default.
• W2763694566 creator A5044018192 @default.
• W2763694566 creator A5045067652 @default.
• W2763694566 creator A5054716149 @default.
• W2763694566 creator A5060002817 @default.
• W2763694566 creator A5082857859 @default.
• W2763694566 creator A5085340844 @default.
• W2763694566 creator A5088725853 @default.
• W2763694566 date "2017-10-11" @default.
• W2763694566 modified "2023-09-27" @default.
• W2763694566 title "Clinicopathological and genetic characteristics of pulmonary large cell carcinoma under 2015 WHO classification: a pilot study" @default.
• W2763694566 cites W1809114427 @default.
• W2763694566 cites W1860395129 @default.
• W2763694566 cites W1953677527 @default.
• W2763694566 cites W1967002514 @default.
• W2763694566 cites W1977332018 @default.
• W2763694566 cites W1985496063 @default.
• W2763694566 cites W1988620211 @default.
• W2763694566 cites W2057788056 @default.
• W2763694566 cites W2084753218 @default.
• W2763694566 cites W2099725888 @default.
• W2763694566 cites W2135311177 @default.
• W2763694566 cites W2139236349 @default.
• W2763694566 cites W2145835533 @default.
• W2763694566 cites W2156728903 @default.
• W2763694566 cites W2161821474 @default.
• W2763694566 cites W2166749501 @default.
• W2763694566 cites W2251438188 @default.
• W2763694566 cites W2264948115 @default.
• W2763694566 cites W2289295511 @default.
• W2763694566 doi "https://doi.org/10.18632/oncotarget.21736" @default.
• W2763694566 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5725061" @default.
• W2763694566 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29246019" @default.
• W2763694566 hasPublicationYear "2017" @default.
• W2763694566 type Work @default.
• W2763694566 sameAs 2763694566 @default.
• W2763694566 citedByCount "4" @default.
• W2763694566 countsByYear W27636945662020 @default.
• W2763694566 countsByYear W27636945662022 @default.
• W2763694566 crossrefType "journal-article" @default.
• W2763694566 hasAuthorship W2763694566A5020160235 @default.
• W2763694566 hasAuthorship W2763694566A5029297164 @default.
• W2763694566 hasAuthorship W2763694566A5035705128 @default.
• W2763694566 hasAuthorship W2763694566A5044018192 @default.
• W2763694566 hasAuthorship W2763694566A5045067652 @default.
• W2763694566 hasAuthorship W2763694566A5054716149 @default.
• W2763694566 hasAuthorship W2763694566A5060002817 @default.
• W2763694566 hasAuthorship W2763694566A5082857859 @default.
• W2763694566 hasAuthorship W2763694566A5085340844 @default.
• W2763694566 hasAuthorship W2763694566A5088725853 @default.
• W2763694566 hasBestOaLocation W27636945661 @default.
• W2763694566 hasConcept C104317684 @default.
• W2763694566 hasConcept C121608353 @default.
• W2763694566 hasConcept C126322002 @default.
• W2763694566 hasConcept C143998085 @default.
• W2763694566 hasConcept C190283241 @default.
• W2763694566 hasConcept C2776256026 @default.
• W2763694566 hasConcept C2777546739 @default.
• W2763694566 hasConcept C2777609662 @default.
• W2763694566 hasConcept C2781187634 @default.
• W2763694566 hasConcept C2994225774 @default.
• W2763694566 hasConcept C501734568 @default.
• W2763694566 hasConcept C526805850 @default.
• W2763694566 hasConcept C54355233 @default.
• W2763694566 hasConcept C71924100 @default.
• W2763694566 hasConcept C86554907 @default.
• W2763694566 hasConcept C86803240 @default.
• W2763694566 hasConceptScore W2763694566C104317684 @default.
• W2763694566 hasConceptScore W2763694566C121608353 @default.
• W2763694566 hasConceptScore W2763694566C126322002 @default.
• W2763694566 hasConceptScore W2763694566C143998085 @default.
• W2763694566 hasConceptScore W2763694566C190283241 @default.
• W2763694566 hasConceptScore W2763694566C2776256026 @default.
• W2763694566 hasConceptScore W2763694566C2777546739 @default.
• W2763694566 hasConceptScore W2763694566C2777609662 @default.
• W2763694566 hasConceptScore W2763694566C2781187634 @default.
• W2763694566 hasConceptScore W2763694566C2994225774 @default.
• W2763694566 hasConceptScore W2763694566C501734568 @default.
• W2763694566 hasConceptScore W2763694566C526805850 @default.
• W2763694566 hasConceptScore W2763694566C54355233 @default.
• W2763694566 hasConceptScore W2763694566C71924100 @default.
• W2763694566 hasConceptScore W2763694566C86554907 @default.
• W2763694566 hasConceptScore W2763694566C86803240 @default.
• W2763694566 hasIssue "59" @default.
• W2763694566 hasLocation W27636945661 @default.
• W2763694566 hasLocation W27636945662 @default.
• W2763694566 hasLocation W27636945663 @default.
• W2763694566 hasLocation W27636945664 @default.
• W2763694566 hasOpenAccess W2763694566 @default.
• W2763694566 hasPrimaryLocation W27636945661 @default.
• W2763694566 hasRelatedWork W1503485936 @default.
• W2763694566 hasRelatedWork W1998068438 @default.
• W2763694566 hasRelatedWork W2118325336 @default.
• W2763694566 hasRelatedWork W2121070670 @default.

• next