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- W2763791337 abstract "An efficient protocol for the synthesis of substituted 1,2,3‐triazol‐9 H ‐purines via copper (I)‐catalyzed click chemistry of 2,6‐dichloropurine with aromatic azide has been reported. A wide range of 1,4‐disubstituted triazoles ( N ‐9 substituted purines) was accessible in good‐to‐excellent yields with remarkable functional group tolerance. The base‐catalyst ratio was tuned to achieve optimum reaction condition (>95% conversion and purity in most cases). Furthermore, the structure of 4i has been unambiguously assigned by X‐ray crystallographic study to yield structural information on the 1,3‐dipoles entering the reaction." @default.
- W2763791337 created "2017-10-20" @default.
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- W2763791337 date "2017-10-13" @default.
- W2763791337 modified "2023-10-12" @default.
- W2763791337 title "Synthesis of Purine-based Triazoles by Copper (I)-catalyzed Huisgen Azide-Alkyne Cycloaddition Reaction" @default.
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- W2763791337 doi "https://doi.org/10.1002/jhet.3025" @default.
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