FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2763899995> ?p ?o ?g. }

• W2763899995 endingPage "73" @default.
• W2763899995 startingPage "64" @default.
• W2763899995 abstract "Previous studies suggest an association between Disrupted in schizophrenia 1 (DISC1) polymorphisms and schizophrenia (SCZ). However, the available data are often inconsistent, regarding the difference in sample size, ethnicity, genotyping method, etc. Thus, we carried out a meta-analysis to determine whether DISC1 polymorphisms contributed susceptibility to SCZ.A methodical literature review was operated using the English and Chinese core electronic databases. Odds ratios (ORs) with 95% confidence intervals (CIs) were applied to determine the correlation between DISC1 gene polymorphisms and SCZ susceptibility. Subgroup analyses were carried out by stratification of ethnicity. P values were Bonferroni adjusted to account for multiple testing. Publication bias was evaluated by funnel plots, Egger's test and the trim and fill method.Meta-analyses results suggested that DISC1 polymorphisms (rs821616 and rs821597) increased SCZ risk in overall populations. In subgroups of ethnicity, DISC1 polymorphisms (rs821616 and rs821597) was associated with susceptibility to SCZ among the Chinese population (for rs821616: TT+AT vs. AA: OR=1.338, 95% CI=1.124-1.592, P=0.001; T vs. A: OR=1.300, 95% CI=1.124-1.504, P<0.000; for rs821597: AA+AG vs. GG: OR=1.508, 95% CI=1.268-1.794, P<0.001; A vs. G: OR=1.345, 95% CI=1.184-1.527, P<0.001). A positive correlation was also observed between the single marker rs821616 and SCZ among the Japanese population in the recessive model (TT vs. AT+AA: OR=1.524, 95% CI=1.185-1.959, P=0.001). There was no significant relationship between other DISC1 polymorphisms (rs3738401, rs2273890, rs3738398, rs3738402, rs2492367, rs843979, rs3737597, rs4658971, rs1538979, rs1000731 and rs3738399) and SCZ.DISC1 polymorphisms increased a risk of SCZ, especially in the Chinese population. In order to further corroborate our findings, large well-designed epidemiological studies are needed." @default.
• W2763899995 created "2017-10-20" @default.
• W2763899995 creator A5017627759 @default.
• W2763899995 creator A5026515345 @default.
• W2763899995 creator A5033080900 @default.
• W2763899995 creator A5060015764 @default.
• W2763899995 creator A5064207906 @default.
• W2763899995 creator A5065208984 @default.
• W2763899995 creator A5070255904 @default.
• W2763899995 date "2018-02-01" @default.
• W2763899995 modified "2023-10-16" @default.
• W2763899995 title "Gene polymorphisms of DISC1 is associated with schizophrenia: Evidence from a meta-analysis" @default.
• W2763899995 cites W1845875257 @default.
• W2763899995 cites W1904790012 @default.
• W2763899995 cites W1935445927 @default.
• W2763899995 cites W1964435302 @default.
• W2763899995 cites W1967291450 @default.
• W2763899995 cites W1981727510 @default.
• W2763899995 cites W1983436768 @default.
• W2763899995 cites W1985190426 @default.
• W2763899995 cites W1992993436 @default.
• W2763899995 cites W1994423580 @default.
• W2763899995 cites W1994676070 @default.
• W2763899995 cites W1998880912 @default.
• W2763899995 cites W1999137631 @default.
• W2763899995 cites W2002420618 @default.
• W2763899995 cites W2002513226 @default.
• W2763899995 cites W2003346255 @default.
• W2763899995 cites W2005848760 @default.
• W2763899995 cites W2009827279 @default.
• W2763899995 cites W2011741232 @default.
• W2763899995 cites W2019465651 @default.
• W2763899995 cites W2021053325 @default.
• W2763899995 cites W2023171821 @default.
• W2763899995 cites W2028034898 @default.
• W2763899995 cites W2029087634 @default.
• W2763899995 cites W2032373466 @default.
• W2763899995 cites W2033585778 @default.
• W2763899995 cites W2033971592 @default.
• W2763899995 cites W2034611055 @default.
• W2763899995 cites W2040214825 @default.
• W2763899995 cites W2048619991 @default.
• W2763899995 cites W2053196964 @default.
• W2763899995 cites W2061589611 @default.
• W2763899995 cites W2065941654 @default.
• W2763899995 cites W2069011875 @default.
• W2763899995 cites W2088828386 @default.
• W2763899995 cites W2089529427 @default.
• W2763899995 cites W2098597355 @default.
• W2763899995 cites W2108043593 @default.
• W2763899995 cites W2112007464 @default.
• W2763899995 cites W2122568737 @default.
• W2763899995 cites W2129301819 @default.
• W2763899995 cites W2130969514 @default.
• W2763899995 cites W2135772494 @default.
• W2763899995 cites W2140639630 @default.
• W2763899995 cites W2157823046 @default.
• W2763899995 cites W2158991820 @default.
• W2763899995 cites W2159703558 @default.
• W2763899995 cites W2160003798 @default.
• W2763899995 cites W2165220417 @default.
• W2763899995 cites W2165517240 @default.
• W2763899995 cites W2171814108 @default.
• W2763899995 cites W2221531846 @default.
• W2763899995 cites W2400983198 @default.
• W2763899995 cites W2409333712 @default.
• W2763899995 doi "https://doi.org/10.1016/j.pnpbp.2017.10.008" @default.
• W2763899995 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29031911" @default.
• W2763899995 hasPublicationYear "2018" @default.
• W2763899995 type Work @default.
• W2763899995 sameAs 2763899995 @default.
• W2763899995 citedByCount "23" @default.
• W2763899995 countsByYear W27638999952018 @default.
• W2763899995 countsByYear W27638999952019 @default.
• W2763899995 countsByYear W27638999952020 @default.
• W2763899995 countsByYear W27638999952021 @default.
• W2763899995 countsByYear W27638999952022 @default.
• W2763899995 countsByYear W27638999952023 @default.
• W2763899995 crossrefType "journal-article" @default.
• W2763899995 hasAuthorship W2763899995A5017627759 @default.
• W2763899995 hasAuthorship W2763899995A5026515345 @default.
• W2763899995 hasAuthorship W2763899995A5033080900 @default.
• W2763899995 hasAuthorship W2763899995A5060015764 @default.
• W2763899995 hasAuthorship W2763899995A5064207906 @default.
• W2763899995 hasAuthorship W2763899995A5065208984 @default.
• W2763899995 hasAuthorship W2763899995A5070255904 @default.
• W2763899995 hasConcept C104317684 @default.
• W2763899995 hasConcept C126322002 @default.
• W2763899995 hasConcept C135763542 @default.
• W2763899995 hasConcept C143998085 @default.
• W2763899995 hasConcept C149737253 @default.
• W2763899995 hasConcept C156957248 @default.
• W2763899995 hasConcept C180754005 @default.
• W2763899995 hasConcept C2777568134 @default.
• W2763899995 hasConcept C2780439572 @default.
• W2763899995 hasConcept C2908647359 @default.
• W2763899995 hasConcept C31467283 @default.
• W2763899995 hasConcept C44249647 @default.

• next