Matches in SemOpenAlex for { <https://semopenalex.org/work/W2764127669> ?p ?o ?g. }
- W2764127669 endingPage "594" @default.
- W2764127669 startingPage "583" @default.
- W2764127669 abstract "BackgroundMyocardial dysfunction may contribute to circulatory failure in sepsis. There is growing evidence of an association between left ventricular diastolic dysfunction (LVDD) and mortality in septic patients. Utilizing echocardiography, we know that tissue Doppler imaging (TDI) variables e′ and E/e′ are reliable predictors of LVDD and are useful measurements to estimate left ventricular (LV) filling pressures.MethodsWe conducted a systematic review and meta-analysis to investigate the association of e′ and E/e′ with mortality of patients with severe sepsis or septic shock. In the primary analysis, we included studies providing transthoracic TDI data for e′ and E/e′ and their association with mortality. Subgroup analyses were conducted according to myocardial regional focus of TDI assessment (septal, lateral or averaged). Three secondary analyses were performed: one included data from a transoesophageal study, another excluded studies reporting data at a very early (<6 h) or late (>48 h) stage following diagnosis, and the third pooled data only from studies excluding patients with heart valve disease.ResultsThe primary analysis included 16 studies with 1507 patients with severe sepsis and/or septic shock. A significant association was found between mortality and both lower e′ [standard mean difference (SMD) 0.33; 95% confidence interval (CI): 0.05, 0.62; P=0.02] and higher E/e′ (SMD –0.33; 95% CI: –0.57, –0.10; P=0.006). In the subgroup analyses, only the lateral TDI values showed significant association with mortality (lower e′ SMD 0.45; 95% CI: 0.11, 0.78; P=0.009; higher E/e′ SMD –0.49; 95% CI: –0.76, –0.22; P=0.0003). The findings of the primary analysis were confirmed by all secondary analyses.ConclusionsThere is a strong association between both lower e′ and higher E/e′ and mortality in septic patients." @default.
- W2764127669 created "2017-10-20" @default.
- W2764127669 creator A5025661709 @default.
- W2764127669 creator A5041328216 @default.
- W2764127669 creator A5061414494 @default.
- W2764127669 creator A5077792611 @default.
- W2764127669 creator A5086871368 @default.
- W2764127669 creator A5086939755 @default.
- W2764127669 creator A5087896529 @default.
- W2764127669 date "2017-10-01" @default.
- W2764127669 modified "2023-10-11" @default.
- W2764127669 title "Tissue Doppler assessment of diastolic function and relationship with mortality in critically ill septic patients: a systematic review and meta-analysis" @default.
- W2764127669 cites W1140934354 @default.
- W2764127669 cites W1192884186 @default.
- W2764127669 cites W1511208491 @default.
- W2764127669 cites W1537972189 @default.
- W2764127669 cites W1965559094 @default.
- W2764127669 cites W1966952799 @default.
- W2764127669 cites W1979056246 @default.
- W2764127669 cites W1979113861 @default.
- W2764127669 cites W1979945050 @default.
- W2764127669 cites W1991085306 @default.
- W2764127669 cites W1995076573 @default.
- W2764127669 cites W2004201059 @default.
- W2764127669 cites W2014826453 @default.
- W2764127669 cites W2018233860 @default.
- W2764127669 cites W2018742759 @default.
- W2764127669 cites W2021034100 @default.
- W2764127669 cites W2024166458 @default.
- W2764127669 cites W2026750684 @default.
- W2764127669 cites W2028675203 @default.
- W2764127669 cites W2033989169 @default.
- W2764127669 cites W2039096112 @default.
- W2764127669 cites W2039662339 @default.
- W2764127669 cites W2041601376 @default.
- W2764127669 cites W2046425814 @default.
- W2764127669 cites W2053737928 @default.
- W2764127669 cites W2064214275 @default.
- W2764127669 cites W2074308834 @default.
- W2764127669 cites W2080939599 @default.
- W2764127669 cites W2086780538 @default.
- W2764127669 cites W2088523521 @default.
- W2764127669 cites W2089923812 @default.
- W2764127669 cites W2097916086 @default.
- W2764127669 cites W2109857015 @default.
- W2764127669 cites W2113961694 @default.
- W2764127669 cites W2116100552 @default.
- W2764127669 cites W2122029195 @default.
- W2764127669 cites W2122297844 @default.
- W2764127669 cites W2125435699 @default.
- W2764127669 cites W2130621776 @default.
- W2764127669 cites W2139168718 @default.
- W2764127669 cites W2142559508 @default.
- W2764127669 cites W2143034699 @default.
- W2764127669 cites W2143674041 @default.
- W2764127669 cites W2147381349 @default.
- W2764127669 cites W2148405482 @default.
- W2764127669 cites W2151115737 @default.
- W2764127669 cites W2151607420 @default.
- W2764127669 cites W2157101465 @default.
- W2764127669 cites W2157823046 @default.
- W2764127669 cites W2158596257 @default.
- W2764127669 cites W2231570112 @default.
- W2764127669 cites W2278600110 @default.
- W2764127669 cites W2280404143 @default.
- W2764127669 cites W2282181907 @default.
- W2764127669 cites W2303241606 @default.
- W2764127669 cites W2323050154 @default.
- W2764127669 cites W2340102426 @default.
- W2764127669 cites W2341870648 @default.
- W2764127669 cites W2408821149 @default.
- W2764127669 cites W2442246762 @default.
- W2764127669 cites W2471327176 @default.
- W2764127669 cites W2490034547 @default.
- W2764127669 cites W2509900314 @default.
- W2764127669 cites W2576440140 @default.
- W2764127669 cites W4206174721 @default.
- W2764127669 cites W4233094474 @default.
- W2764127669 cites W962524464 @default.
- W2764127669 doi "https://doi.org/10.1093/bja/aex254" @default.
- W2764127669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29121301" @default.
- W2764127669 hasPublicationYear "2017" @default.
- W2764127669 type Work @default.
- W2764127669 sameAs 2764127669 @default.
- W2764127669 citedByCount "95" @default.
- W2764127669 countsByYear W27641276692017 @default.
- W2764127669 countsByYear W27641276692018 @default.
- W2764127669 countsByYear W27641276692019 @default.
- W2764127669 countsByYear W27641276692020 @default.
- W2764127669 countsByYear W27641276692021 @default.
- W2764127669 countsByYear W27641276692022 @default.
- W2764127669 countsByYear W27641276692023 @default.
- W2764127669 crossrefType "journal-article" @default.
- W2764127669 hasAuthorship W2764127669A5025661709 @default.
- W2764127669 hasAuthorship W2764127669A5041328216 @default.
- W2764127669 hasAuthorship W2764127669A5061414494 @default.
- W2764127669 hasAuthorship W2764127669A5077792611 @default.
- W2764127669 hasAuthorship W2764127669A5086871368 @default.