Matches in SemOpenAlex for { <https://semopenalex.org/work/W2764272238> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2764272238 endingPage "1695" @default.
- W2764272238 startingPage "1676" @default.
- W2764272238 abstract "Introduction: Salivary gland tumors are extremely rare neoplasms. Given their pathohistological image, these tumors represent a great diagnostic challenge. The aim of our study was to differentiate these three tumor types by applying the immunohistochemical and morphometric analysis. Material and Methods: The entire study was conducted at the Center for Pathology and Pathological Anatomy in Niš. The study included 44 tumors, 20 pleomorphic adenomas, 12 basal cells adenomas and 12 polymorphous low-grade adenocarcinomas. The expression of Ki67, p53 and HER-2 antigens, as proliferation markers, was analyzed. The differential diagnostics also included the analysis of the expression of CEA, EMA, GFAP, p63, vimentin, CK14, α-SMA, S-100 protein and WT1 antigen. The morphometric analysis was done in the program pack 'ImageJ' version 1.43u. The statistical analysis of data was done in the program pack SPSS 15.0. Results: Neoplastic cells in pleomorphic adenoma showed a strong expression of GFAP (20/20), p63 (20/20), WT1 (20/20), vimentin (18/20) and S100 (16/20). Diffuse expression of CK14 (12/12) was present in the group of 12 polymorphous low-grade adenocarcinomas. S-100, vimentin and EMA were absolutely expressed, whereas α-SMA was negative. Basal cell adenoma showed negativity to S-100, CEA, p63 and vimentin. The analysis of the proliferative Ki67 index values pointed to a statistically significant difference in the pleomorphic adenoma group, which was associated with a frequent recurrence of this benign tumor. The analysis of morphometric characteristics showed higher values in the polymorphous low-grade adenocarcinoma group, but statistically significant differences were found only for the Feret diameter and the integrated optical density (p < 0.05). As for the basal cell adenoma group, tumor cells showed statistically higher values for the integrated optical density (p < 0.001). Conclusion: Apart from the basic micromorphological analysis, the differential analysis of salivary gland tumors also requires the immunohistochemical analysis as well as the monitoring of morphometric characteristics of these tumors' nuclei." @default.
- W2764272238 created "2017-10-20" @default.
- W2764272238 creator A5004390974 @default.
- W2764272238 creator A5014378946 @default.
- W2764272238 creator A5023482572 @default.
- W2764272238 creator A5023575586 @default.
- W2764272238 creator A5023894771 @default.
- W2764272238 creator A5027474484 @default.
- W2764272238 creator A5029737952 @default.
- W2764272238 creator A5045190734 @default.
- W2764272238 creator A5053759351 @default.
- W2764272238 creator A5069700792 @default.
- W2764272238 creator A5087554349 @default.
- W2764272238 date "2017-01-01" @default.
- W2764272238 modified "2023-09-27" @default.
- W2764272238 title "Immunohistochemical and karyometric similarities and differences of salivary gland tumors between pleomorphic adenoma, basal cell adenoma and polymorphous low grade adenocarcinoma" @default.
- W2764272238 doi "https://doi.org/10.5937/asn1775676z" @default.
- W2764272238 hasPublicationYear "2017" @default.
- W2764272238 type Work @default.
- W2764272238 sameAs 2764272238 @default.
- W2764272238 citedByCount "1" @default.
- W2764272238 countsByYear W27642722382020 @default.
- W2764272238 crossrefType "journal-article" @default.
- W2764272238 hasAuthorship W2764272238A5004390974 @default.
- W2764272238 hasAuthorship W2764272238A5014378946 @default.
- W2764272238 hasAuthorship W2764272238A5023482572 @default.
- W2764272238 hasAuthorship W2764272238A5023575586 @default.
- W2764272238 hasAuthorship W2764272238A5023894771 @default.
- W2764272238 hasAuthorship W2764272238A5027474484 @default.
- W2764272238 hasAuthorship W2764272238A5029737952 @default.
- W2764272238 hasAuthorship W2764272238A5045190734 @default.
- W2764272238 hasAuthorship W2764272238A5053759351 @default.
- W2764272238 hasAuthorship W2764272238A5069700792 @default.
- W2764272238 hasAuthorship W2764272238A5087554349 @default.
- W2764272238 hasBestOaLocation W27642722381 @default.
- W2764272238 hasConcept C121608353 @default.
- W2764272238 hasConcept C126322002 @default.
- W2764272238 hasConcept C134018914 @default.
- W2764272238 hasConcept C142724271 @default.
- W2764272238 hasConcept C147447768 @default.
- W2764272238 hasConcept C204232928 @default.
- W2764272238 hasConcept C207886595 @default.
- W2764272238 hasConcept C2777428134 @default.
- W2764272238 hasConcept C2778024521 @default.
- W2764272238 hasConcept C2778937882 @default.
- W2764272238 hasConcept C2779012181 @default.
- W2764272238 hasConcept C2779306644 @default.
- W2764272238 hasConcept C2781182431 @default.
- W2764272238 hasConcept C2781437628 @default.
- W2764272238 hasConcept C2910938049 @default.
- W2764272238 hasConcept C71924100 @default.
- W2764272238 hasConcept C86803240 @default.
- W2764272238 hasConceptScore W2764272238C121608353 @default.
- W2764272238 hasConceptScore W2764272238C126322002 @default.
- W2764272238 hasConceptScore W2764272238C134018914 @default.
- W2764272238 hasConceptScore W2764272238C142724271 @default.
- W2764272238 hasConceptScore W2764272238C147447768 @default.
- W2764272238 hasConceptScore W2764272238C204232928 @default.
- W2764272238 hasConceptScore W2764272238C207886595 @default.
- W2764272238 hasConceptScore W2764272238C2777428134 @default.
- W2764272238 hasConceptScore W2764272238C2778024521 @default.
- W2764272238 hasConceptScore W2764272238C2778937882 @default.
- W2764272238 hasConceptScore W2764272238C2779012181 @default.
- W2764272238 hasConceptScore W2764272238C2779306644 @default.
- W2764272238 hasConceptScore W2764272238C2781182431 @default.
- W2764272238 hasConceptScore W2764272238C2781437628 @default.
- W2764272238 hasConceptScore W2764272238C2910938049 @default.
- W2764272238 hasConceptScore W2764272238C71924100 @default.
- W2764272238 hasConceptScore W2764272238C86803240 @default.
- W2764272238 hasIssue "75" @default.
- W2764272238 hasLocation W27642722381 @default.
- W2764272238 hasLocation W27642722382 @default.
- W2764272238 hasOpenAccess W2764272238 @default.
- W2764272238 hasPrimaryLocation W27642722381 @default.
- W2764272238 hasRelatedWork W1972257377 @default.
- W2764272238 hasRelatedWork W1989845789 @default.
- W2764272238 hasRelatedWork W2029559096 @default.
- W2764272238 hasRelatedWork W2044279975 @default.
- W2764272238 hasRelatedWork W2079742895 @default.
- W2764272238 hasRelatedWork W2162663678 @default.
- W2764272238 hasRelatedWork W2346103388 @default.
- W2764272238 hasRelatedWork W2463033561 @default.
- W2764272238 hasRelatedWork W2764272238 @default.
- W2764272238 hasRelatedWork W90099573 @default.
- W2764272238 hasVolume "33" @default.
- W2764272238 isParatext "false" @default.
- W2764272238 isRetracted "false" @default.
- W2764272238 magId "2764272238" @default.
- W2764272238 workType "article" @default.