Matches in SemOpenAlex for { <https://semopenalex.org/work/W2764336456> ?p ?o ?g. }
- W2764336456 endingPage "1912" @default.
- W2764336456 startingPage "1904" @default.
- W2764336456 abstract "The function of long noncoding RNAs (lncRNAs) in liver injury resulted by dengue virus (DENV) infection have not yet been explored. The differential expression profiles of lncRNAs (as well as mRNAs) in the L-02 liver cells infected by DENV1, DENV2, or uninfected were compared and analyzed after a high throughput RNA seq. The significantly up-regulated and down-regulated lncRNAs (or mRNAs) resulted by DENV infection were identified with a cutoff value at log2 (ratio) ≥ 1.5 and log2 (ratio) ≤ −1.5 (ratio = the reads of the lncRNAs or mRNAs from the infection groups divided by the reads from the control group). Several differentially expressed lncRNAs were verified with reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR). Target gene analysis, pre-miRNA prediction, and the lncRNA-mRNA co-expression network construction were performed to predict the function of the differentially expressed lncRNAs. The differentially expressed lncRNAs were associated with biosynthesis, DNA/RNA related processes, inhibition of estrogen signaling pathway, sterol biosynthetic process, protein dimerization activity, vesicular fraction in DENV1 infection group; and with protein secretion, methyltransferase process, host cell cytoskeleton reorganization and the small GTPase Ras superfamily, inhibition of cell proliferation, induction of apoptosis in DENV2 infection. LncRNAs might be novel diagnostic markers and targets for further researches on dengue infection and liver injury resulted by dengue virus." @default.
- W2764336456 created "2017-10-20" @default.
- W2764336456 creator A5008473333 @default.
- W2764336456 creator A5013734736 @default.
- W2764336456 creator A5018137098 @default.
- W2764336456 creator A5028526811 @default.
- W2764336456 creator A5030916345 @default.
- W2764336456 creator A5031300564 @default.
- W2764336456 date "2017-12-06" @default.
- W2764336456 modified "2023-10-18" @default.
- W2764336456 title "The Differential Expression and Possible Function of Long Noncoding RNAs in Liver Cells Infected by Dengue Virus" @default.
- W2764336456 cites W132536692 @default.
- W2764336456 cites W1439006730 @default.
- W2764336456 cites W1536340771 @default.
- W2764336456 cites W1603555502 @default.
- W2764336456 cites W1630015606 @default.
- W2764336456 cites W1718835756 @default.
- W2764336456 cites W1788527284 @default.
- W2764336456 cites W1978967539 @default.
- W2764336456 cites W1990629752 @default.
- W2764336456 cites W1993574813 @default.
- W2764336456 cites W2006415869 @default.
- W2764336456 cites W2010060324 @default.
- W2764336456 cites W2011575027 @default.
- W2764336456 cites W2016302314 @default.
- W2764336456 cites W2028793338 @default.
- W2764336456 cites W2034926804 @default.
- W2764336456 cites W2043066204 @default.
- W2764336456 cites W2055907204 @default.
- W2764336456 cites W2058970225 @default.
- W2764336456 cites W2059802531 @default.
- W2764336456 cites W2063311100 @default.
- W2764336456 cites W2067193640 @default.
- W2764336456 cites W2080635248 @default.
- W2764336456 cites W2082580788 @default.
- W2764336456 cites W2099784004 @default.
- W2764336456 cites W2111380632 @default.
- W2764336456 cites W2124985265 @default.
- W2764336456 cites W2131222241 @default.
- W2764336456 cites W2132316389 @default.
- W2764336456 cites W2135695964 @default.
- W2764336456 cites W2140729960 @default.
- W2764336456 cites W2141260115 @default.
- W2764336456 cites W2150142873 @default.
- W2764336456 cites W2157399331 @default.
- W2764336456 cites W2158541290 @default.
- W2764336456 cites W2161271012 @default.
- W2764336456 cites W2161361135 @default.
- W2764336456 cites W2164082417 @default.
- W2764336456 cites W2167381190 @default.
- W2764336456 cites W2171797570 @default.
- W2764336456 cites W2213458517 @default.
- W2764336456 cites W2220559134 @default.
- W2764336456 cites W2267988404 @default.
- W2764336456 cites W2474614962 @default.
- W2764336456 doi "https://doi.org/10.4269/ajtmh.17-0307" @default.
- W2764336456 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5805055" @default.
- W2764336456 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29016307" @default.
- W2764336456 hasPublicationYear "2017" @default.
- W2764336456 type Work @default.
- W2764336456 sameAs 2764336456 @default.
- W2764336456 citedByCount "12" @default.
- W2764336456 countsByYear W27643364562018 @default.
- W2764336456 countsByYear W27643364562019 @default.
- W2764336456 countsByYear W27643364562020 @default.
- W2764336456 countsByYear W27643364562021 @default.
- W2764336456 countsByYear W27643364562022 @default.
- W2764336456 crossrefType "journal-article" @default.
- W2764336456 hasAuthorship W2764336456A5008473333 @default.
- W2764336456 hasAuthorship W2764336456A5013734736 @default.
- W2764336456 hasAuthorship W2764336456A5018137098 @default.
- W2764336456 hasAuthorship W2764336456A5028526811 @default.
- W2764336456 hasAuthorship W2764336456A5030916345 @default.
- W2764336456 hasAuthorship W2764336456A5031300564 @default.
- W2764336456 hasBestOaLocation W27643364561 @default.
- W2764336456 hasConcept C104317684 @default.
- W2764336456 hasConcept C150194340 @default.
- W2764336456 hasConcept C153911025 @default.
- W2764336456 hasConcept C159047783 @default.
- W2764336456 hasConcept C2779635636 @default.
- W2764336456 hasConcept C533803919 @default.
- W2764336456 hasConcept C54355233 @default.
- W2764336456 hasConcept C62203573 @default.
- W2764336456 hasConcept C67705224 @default.
- W2764336456 hasConcept C86803240 @default.
- W2764336456 hasConcept C95444343 @default.
- W2764336456 hasConceptScore W2764336456C104317684 @default.
- W2764336456 hasConceptScore W2764336456C150194340 @default.
- W2764336456 hasConceptScore W2764336456C153911025 @default.
- W2764336456 hasConceptScore W2764336456C159047783 @default.
- W2764336456 hasConceptScore W2764336456C2779635636 @default.
- W2764336456 hasConceptScore W2764336456C533803919 @default.
- W2764336456 hasConceptScore W2764336456C54355233 @default.
- W2764336456 hasConceptScore W2764336456C62203573 @default.
- W2764336456 hasConceptScore W2764336456C67705224 @default.
- W2764336456 hasConceptScore W2764336456C86803240 @default.
- W2764336456 hasConceptScore W2764336456C95444343 @default.
- W2764336456 hasIssue "6" @default.