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• W2765059218 abstract "Computational models for small experimental animals are important in medical imaging and radiation dosimetry researches. The boundary representation method by use of nonuniform rational B-splines (NURBS) is adopted in this paper to develop a rat computational phantom based on the previously obtained segmentation data for cryosectional color photographic images of an adult male Sprague-Dawley rat. Continuous two-dimensional contours for a total of 14 major structures were outlined from the downscaled anatomical atlas, corresponding to a voxel size of 0.2 x 0.2 x 0.2 mm 3 and stacked to reconstruct the three-dimensional (3-D) shapes. The NURBS model was then appropriately fitted through the surface of each organ. Monte Carlo simulation of cone beam X-ray computed tomography was performed focusing on the thorax region to demonstrate the usefulness of the computational phantom in radiological imaging. The integrated whole-body geometry is presented with smooth internal and exterior boundaries. Organ centroid coordinates and volume information are tabulated for future comparison purposes. The rat phantom can be used in 3-D dose calculation and other computational applications as well." @default.
• W2765059218 created "2017-10-27" @default.
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• W2765059218 date "2009-01-01" @default.
• W2765059218 modified "2023-09-26" @default.
• W2765059218 title "Development of a Rat Computational Phantom Using Boundary Representation Method for Monte Carlo Simulation in Radiological Imaging: A mathematical method that has been adapted to simulate use of x-ray beam operation shows promise for development of computer models used for radiation therapy and medical image research" @default.
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