FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2765133082> ?p ?o ?g. }

• W2765133082 endingPage "283" @default.
• W2765133082 startingPage "278" @default.
• W2765133082 abstract "The objective of this work is to find out whether there is a relation between the expression of TLR4 and fibrosis progression in chronic HCV patients.Toll-like Receptor 4 (TLR4) is a pattern recognition receptor whose activation results in the production of several pro-inflammatory cytokines.Fifty patients with chronic HCV were included. They were divided into group A: 40 patients (F1-F4) and group B (control group) which included ten patients (F0) based on fibroscan value. All patients were exposed to clinical and laboratory evaluations preliminary to antiviral therapy, assessment of TLR4 mRNA by Real Time- PCR.Twenty-eight males and 22 females with a mean age 28.9±6.1 years. The mean TLR4 expression is 11.2±7.4 folds, TLR4 expression in F0 group is 2.8±1.9, in F1 group 4.8±1.5, F2 group 10.2±2.5, F3 group 16.8±1.5 and in F4 21.3±3.6 folds (p<0.001). TLR4 showed a positive correlation with age, fibrosis stage, HCV RNA, serum transaminases, total bilirubin and prothrombin time, a negative correlation with platelet count and serum albumin. Fibrosis progression was independently associated with TLR4 expression (β=0. 648, P<0.0001), RNA (β= 0.160, P =0.001) and platelet count (β= -0.248, P = 0.004).The expression of TLR4 is highly correlated with the fibrosis progression; TLR4 may be a potential target for drugs to limit the progression of fibrosis." @default.
• W2765133082 created "2017-11-10" @default.
• W2765133082 creator A5003985234 @default.
• W2765133082 creator A5010957210 @default.
• W2765133082 creator A5026453528 @default.
• W2765133082 creator A5030226365 @default.
• W2765133082 creator A5078206971 @default.
• W2765133082 creator A5079544585 @default.
• W2765133082 date "2017-01-01" @default.
• W2765133082 modified "2023-09-25" @default.
• W2765133082 title "The relationship between expression of Toll-like receptor 4 in chronic hepatitis C patients and different stages of liver fibrosis." @default.
• W2765133082 cites W1560110579 @default.
• W2765133082 cites W1787550163 @default.
• W2765133082 cites W1973346087 @default.
• W2765133082 cites W1981724846 @default.
• W2765133082 cites W1988986320 @default.
• W2765133082 cites W2000957301 @default.
• W2765133082 cites W2027387871 @default.
• W2765133082 cites W2040211909 @default.
• W2765133082 cites W2045609373 @default.
• W2765133082 cites W2048422492 @default.
• W2765133082 cites W2062025882 @default.
• W2765133082 cites W2076794498 @default.
• W2765133082 cites W2092206815 @default.
• W2765133082 cites W2094133741 @default.
• W2765133082 cites W2104193042 @default.
• W2765133082 cites W2122664567 @default.
• W2765133082 cites W2123044979 @default.
• W2765133082 cites W2127060044 @default.
• W2765133082 cites W2137729498 @default.
• W2765133082 cites W2138474497 @default.
• W2765133082 cites W2144594946 @default.
• W2765133082 cites W2158129157 @default.
• W2765133082 cites W2164906049 @default.
• W2765133082 cites W4255712601 @default.
• W2765133082 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5758735" @default.
• W2765133082 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29379592" @default.
• W2765133082 hasPublicationYear "2017" @default.
• W2765133082 type Work @default.
• W2765133082 sameAs 2765133082 @default.
• W2765133082 citedByCount "1" @default.
• W2765133082 countsByYear W27651330822020 @default.
• W2765133082 crossrefType "journal-article" @default.
• W2765133082 hasAuthorship W2765133082A5003985234 @default.
• W2765133082 hasAuthorship W2765133082A5010957210 @default.
• W2765133082 hasAuthorship W2765133082A5026453528 @default.
• W2765133082 hasAuthorship W2765133082A5030226365 @default.
• W2765133082 hasAuthorship W2765133082A5078206971 @default.
• W2765133082 hasAuthorship W2765133082A5079544585 @default.
• W2765133082 hasConcept C126322002 @default.
• W2765133082 hasConcept C136449434 @default.
• W2765133082 hasConcept C170493617 @default.
• W2765133082 hasConcept C203014093 @default.
• W2765133082 hasConcept C2522874641 @default.
• W2765133082 hasConcept C2776070231 @default.
• W2765133082 hasConcept C2776709828 @default.
• W2765133082 hasConcept C2780434524 @default.
• W2765133082 hasConcept C2780559512 @default.
• W2765133082 hasConcept C2993667909 @default.
• W2765133082 hasConcept C3020491458 @default.
• W2765133082 hasConcept C71924100 @default.
• W2765133082 hasConcept C90924648 @default.
• W2765133082 hasConceptScore W2765133082C126322002 @default.
• W2765133082 hasConceptScore W2765133082C136449434 @default.
• W2765133082 hasConceptScore W2765133082C170493617 @default.
• W2765133082 hasConceptScore W2765133082C203014093 @default.
• W2765133082 hasConceptScore W2765133082C2522874641 @default.
• W2765133082 hasConceptScore W2765133082C2776070231 @default.
• W2765133082 hasConceptScore W2765133082C2776709828 @default.
• W2765133082 hasConceptScore W2765133082C2780434524 @default.
• W2765133082 hasConceptScore W2765133082C2780559512 @default.
• W2765133082 hasConceptScore W2765133082C2993667909 @default.
• W2765133082 hasConceptScore W2765133082C3020491458 @default.
• W2765133082 hasConceptScore W2765133082C71924100 @default.
• W2765133082 hasConceptScore W2765133082C90924648 @default.
• W2765133082 hasIssue "4" @default.
• W2765133082 hasLocation W27651330821 @default.
• W2765133082 hasOpenAccess W2765133082 @default.
• W2765133082 hasPrimaryLocation W27651330821 @default.
• W2765133082 hasRelatedWork W1987696766 @default.
• W2765133082 hasRelatedWork W2065145796 @default.
• W2765133082 hasRelatedWork W2079015756 @default.
• W2765133082 hasRelatedWork W2079269850 @default.
• W2765133082 hasRelatedWork W2088738784 @default.
• W2765133082 hasRelatedWork W2184621090 @default.
• W2765133082 hasRelatedWork W2191248813 @default.
• W2765133082 hasRelatedWork W2338714053 @default.
• W2765133082 hasRelatedWork W2348891311 @default.
• W2765133082 hasRelatedWork W2362568685 @default.
• W2765133082 hasRelatedWork W2376634598 @default.
• W2765133082 hasRelatedWork W2379634725 @default.
• W2765133082 hasRelatedWork W2409634814 @default.
• W2765133082 hasRelatedWork W2588846415 @default.
• W2765133082 hasRelatedWork W2752974563 @default.
• W2765133082 hasRelatedWork W2922823765 @default.
• W2765133082 hasRelatedWork W2947469317 @default.
• W2765133082 hasRelatedWork W2951163630 @default.
• W2765133082 hasRelatedWork W3021904565 @default.

• next