FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2765156635> ?p ?o ?g. }

• W2765156635 endingPage "41" @default.
• W2765156635 startingPage "34" @default.
• W2765156635 abstract "Reliable, cost-effective, and gold-standard absolute quantification of non-esterified cholesterol in human plasma is of paramount importance in clinical lipidomics and for the monitoring of metabolic health. Here, we compared the performance of three mass spectrometric approaches available for direct detection and quantification of cholesterol in extracts of human plasma. These approaches are high resolution full scan Fourier transform mass spectrometry (FTMS) analysis, parallel reaction monitoring (PRM), and novel multiplexed MS/MS (MSX) technology, where fragments from selected precursor ions are detected simultaneously. Evaluating the performance of these approaches in terms of dynamic quantification range, linearity, and analytical precision showed that the MSX-based approach is superior to that of the FTMS and PRM-based approaches. To further show the efficacy of this approach, we devised a simple routine for extensive plasma lipidome characterization using only 8 μL of plasma, using a new commercially available ready-to-spike-in mixture with 14 synthetic lipid standards, and executing a single 6 min sample injection with combined MSX analysis for cholesterol quantification and FTMS analysis for quantification of sterol esters, glycerolipids, glycerophospholipids, and sphingolipids. Using this simple routine afforded reproducible and absolute quantification of 200 lipid species encompassing 13 lipid classes in human plasma samples. Notably, the analysis time of this procedure can be shortened for high throughput-oriented clinical lipidomics studies or extended with more advanced MSALL technology (Almeida R. et al., J. Am. Soc. Mass Spectrom. 26, 133-148 [1]) to support in-depth structural elucidation of lipid molecules. Graphical Abstract ᅟ." @default.
• W2765156635 created "2017-11-10" @default.
• W2765156635 creator A5039949303 @default.
• W2765156635 creator A5041867733 @default.
• W2765156635 creator A5084454705 @default.
• W2765156635 date "2017-10-23" @default.
• W2765156635 modified "2023-10-17" @default.
• W2765156635 title "Easy, Fast, and Reproducible Quantification of Cholesterol and Other Lipids in Human Plasma by Combined High Resolution MSX and FTMS Analysis" @default.
• W2765156635 cites W1797739168 @default.
• W2765156635 cites W1978203908 @default.
• W2765156635 cites W1980992560 @default.
• W2765156635 cites W1984954439 @default.
• W2765156635 cites W1988910058 @default.
• W2765156635 cites W1993423688 @default.
• W2765156635 cites W1998295756 @default.
• W2765156635 cites W2011078603 @default.
• W2765156635 cites W2014925652 @default.
• W2765156635 cites W2020740038 @default.
• W2765156635 cites W2058297557 @default.
• W2765156635 cites W2079559417 @default.
• W2765156635 cites W2087250756 @default.
• W2765156635 cites W2087431894 @default.
• W2765156635 cites W2095535218 @default.
• W2765156635 cites W2096717747 @default.
• W2765156635 cites W2102103378 @default.
• W2765156635 cites W2124081847 @default.
• W2765156635 cites W2127469533 @default.
• W2765156635 cites W2131402057 @default.
• W2765156635 cites W2133614954 @default.
• W2765156635 cites W2144460514 @default.
• W2765156635 cites W2146514603 @default.
• W2765156635 cites W2157240187 @default.
• W2765156635 cites W2165729552 @default.
• W2765156635 cites W2166628970 @default.
• W2765156635 cites W2185275183 @default.
• W2765156635 cites W2234558886 @default.
• W2765156635 cites W2420961370 @default.
• W2765156635 cites W2549017958 @default.
• W2765156635 doi "https://doi.org/10.1007/s13361-017-1829-2" @default.
• W2765156635 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29063477" @default.
• W2765156635 hasPublicationYear "2017" @default.
• W2765156635 type Work @default.
• W2765156635 sameAs 2765156635 @default.
• W2765156635 citedByCount "18" @default.
• W2765156635 countsByYear W27651566352018 @default.
• W2765156635 countsByYear W27651566352019 @default.
• W2765156635 countsByYear W27651566352020 @default.
• W2765156635 countsByYear W27651566352021 @default.
• W2765156635 countsByYear W27651566352022 @default.
• W2765156635 countsByYear W27651566352023 @default.
• W2765156635 crossrefType "journal-article" @default.
• W2765156635 hasAuthorship W2765156635A5039949303 @default.
• W2765156635 hasAuthorship W2765156635A5041867733 @default.
• W2765156635 hasAuthorship W2765156635A5084454705 @default.
• W2765156635 hasConcept C113196181 @default.
• W2765156635 hasConcept C138268822 @default.
• W2765156635 hasConcept C154945302 @default.
• W2765156635 hasConcept C162356407 @default.
• W2765156635 hasConcept C185592680 @default.
• W2765156635 hasConcept C2778918659 @default.
• W2765156635 hasConcept C2780241833 @default.
• W2765156635 hasConcept C2780841973 @default.
• W2765156635 hasConcept C2909522894 @default.
• W2765156635 hasConcept C41008148 @default.
• W2765156635 hasConcept C41625074 @default.
• W2765156635 hasConcept C43617362 @default.
• W2765156635 hasConcept C55493867 @default.
• W2765156635 hasConcept C58017582 @default.
• W2765156635 hasConceptScore W2765156635C113196181 @default.
• W2765156635 hasConceptScore W2765156635C138268822 @default.
• W2765156635 hasConceptScore W2765156635C154945302 @default.
• W2765156635 hasConceptScore W2765156635C162356407 @default.
• W2765156635 hasConceptScore W2765156635C185592680 @default.
• W2765156635 hasConceptScore W2765156635C2778918659 @default.
• W2765156635 hasConceptScore W2765156635C2780241833 @default.
• W2765156635 hasConceptScore W2765156635C2780841973 @default.
• W2765156635 hasConceptScore W2765156635C2909522894 @default.
• W2765156635 hasConceptScore W2765156635C41008148 @default.
• W2765156635 hasConceptScore W2765156635C41625074 @default.
• W2765156635 hasConceptScore W2765156635C43617362 @default.
• W2765156635 hasConceptScore W2765156635C55493867 @default.
• W2765156635 hasConceptScore W2765156635C58017582 @default.
• W2765156635 hasFunder F4320309756 @default.
• W2765156635 hasFunder F4320310490 @default.
• W2765156635 hasFunder F4320323799 @default.
• W2765156635 hasIssue "1" @default.
• W2765156635 hasLocation W27651566351 @default.
• W2765156635 hasLocation W27651566352 @default.
• W2765156635 hasOpenAccess W2765156635 @default.
• W2765156635 hasPrimaryLocation W27651566351 @default.
• W2765156635 hasRelatedWork W1569454591 @default.
• W2765156635 hasRelatedWork W1994718777 @default.
• W2765156635 hasRelatedWork W2012966224 @default.
• W2765156635 hasRelatedWork W2063132858 @default.
• W2765156635 hasRelatedWork W2093629098 @default.
• W2765156635 hasRelatedWork W2765260670 @default.
• W2765156635 hasRelatedWork W3001802972 @default.
• W2765156635 hasRelatedWork W3100361502 @default.

• next