Matches in SemOpenAlex for { <https://semopenalex.org/work/W2765156750> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2765156750 abstract "Objective: Leukemia inhibitory factor (LIF) is the most pleiotropic member of the interleukin-6 family of cytokines. It utilises a receptor that consists of the LIF receptor β and gp130 and this receptor complex is also used by ciliary neurotrophic growth factor (CNTF), oncostatin M, cardiotrophin1 (CT1) and cardiotrophin-like cytokine (CLC). Evidence is emerging that LIF may play an important role in airway inflammation. Recurrent wheezing is one of the commonest problems of early childhood and respiratory syncytial virus (RSV) is the most frequent cause of wheezy episodes. Material and Method: The aim of this study was to determine whether LIF has a role in the airway inflammation of wheezy children and its relationship with RSV infection. Results: Serum LIF levels, total IgE levels, RSV-IgM and RSVIgG antibodies were evaluated in wheezy (22F, 18M) and healthy (18F, 20M) infants. RSV-IgM antibodies were detected in 25% of wheezy and 3% of healthy children. RSV-IgG antibodies were detected 35% and 23%, respectively. There was not significant difference in median serum levels of LIF between wheezy and healthy infants. However, median serum LIF level of subjects who were seropositive for RSV-IgM antibodies was significantly higher than those who were seronegative for RSV-IgM antibodies (16 pg/ml vs 10.5 pg/ml; p=0.01). Conclusion: This study suggests that LIF might play a role in early airway inflammation in infants with wheezy RSV infection. " @default.
- W2765156750 created "2017-11-10" @default.
- W2765156750 creator A5013023199 @default.
- W2765156750 creator A5030411483 @default.
- W2765156750 creator A5043841535 @default.
- W2765156750 creator A5091545294 @default.
- W2765156750 creator A5091619375 @default.
- W2765156750 date "2017-01-01" @default.
- W2765156750 modified "2023-10-16" @default.
- W2765156750 title "Serum levels of Leukemia Inhibitory Factor (LIF) in wheezy infants" @default.
- W2765156750 doi "https://doi.org/10.5222/j.child.2017.012" @default.
- W2765156750 hasPublicationYear "2017" @default.
- W2765156750 type Work @default.
- W2765156750 sameAs 2765156750 @default.
- W2765156750 citedByCount "0" @default.
- W2765156750 crossrefType "journal-article" @default.
- W2765156750 hasAuthorship W2765156750A5013023199 @default.
- W2765156750 hasAuthorship W2765156750A5030411483 @default.
- W2765156750 hasAuthorship W2765156750A5043841535 @default.
- W2765156750 hasAuthorship W2765156750A5091545294 @default.
- W2765156750 hasAuthorship W2765156750A5091619375 @default.
- W2765156750 hasBestOaLocation W27651567501 @default.
- W2765156750 hasConcept C106825092 @default.
- W2765156750 hasConcept C11988809 @default.
- W2765156750 hasConcept C126037660 @default.
- W2765156750 hasConcept C126322002 @default.
- W2765156750 hasConcept C159654299 @default.
- W2765156750 hasConcept C203014093 @default.
- W2765156750 hasConcept C2522874641 @default.
- W2765156750 hasConcept C27284151 @default.
- W2765156750 hasConcept C2776042228 @default.
- W2765156750 hasConcept C2776914184 @default.
- W2765156750 hasConcept C2778821649 @default.
- W2765156750 hasConcept C71924100 @default.
- W2765156750 hasConceptScore W2765156750C106825092 @default.
- W2765156750 hasConceptScore W2765156750C11988809 @default.
- W2765156750 hasConceptScore W2765156750C126037660 @default.
- W2765156750 hasConceptScore W2765156750C126322002 @default.
- W2765156750 hasConceptScore W2765156750C159654299 @default.
- W2765156750 hasConceptScore W2765156750C203014093 @default.
- W2765156750 hasConceptScore W2765156750C2522874641 @default.
- W2765156750 hasConceptScore W2765156750C27284151 @default.
- W2765156750 hasConceptScore W2765156750C2776042228 @default.
- W2765156750 hasConceptScore W2765156750C2776914184 @default.
- W2765156750 hasConceptScore W2765156750C2778821649 @default.
- W2765156750 hasConceptScore W2765156750C71924100 @default.
- W2765156750 hasLocation W27651567501 @default.
- W2765156750 hasOpenAccess W2765156750 @default.
- W2765156750 hasPrimaryLocation W27651567501 @default.
- W2765156750 hasRelatedWork W1504928717 @default.
- W2765156750 hasRelatedWork W1899408333 @default.
- W2765156750 hasRelatedWork W1976707950 @default.
- W2765156750 hasRelatedWork W1990473990 @default.
- W2765156750 hasRelatedWork W2012602403 @default.
- W2765156750 hasRelatedWork W2162126249 @default.
- W2765156750 hasRelatedWork W2164711235 @default.
- W2765156750 hasRelatedWork W2168072967 @default.
- W2765156750 hasRelatedWork W2418014279 @default.
- W2765156750 hasRelatedWork W4296627437 @default.
- W2765156750 isParatext "false" @default.
- W2765156750 isRetracted "false" @default.
- W2765156750 magId "2765156750" @default.
- W2765156750 workType "article" @default.