FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2765253206> ?p ?o ?g. }

• W2765253206 endingPage "529" @default.
• W2765253206 startingPage "520" @default.
• W2765253206 abstract "Objective and Background: Local and distant disease recurrence are frequently observed following pancreatic cancer resection, but an improved understanding of resection margin assessment is required to aid tailored therapies. Methods: Analyses were carried out to assess the association between clinical characteristics and margin involvement as well as the effects of individual margin involvement on site of recurrence and overall and recurrence-free survival using individual patient data from the European Study Group for Pancreatic Cancer (ESPAC)-3 randomized controlled trial. Results: There were 1151 patients, of whom 505 (43.9%) had an R1 resection. The median and 95% confidence interval (CI) overall survival was 24.9 (22.9–27.2) months for 646 (56.1%) patients with resection margin negative (R0 >1 mm) tumors, 25.4 (21.6–30.4) months for 146 (12.7%) patients with R1<1 mm positive resection margins, and 18.7 (17.2–21.1) months for 359 (31.2%) patients with R1-direct positive margins ( P < 0.001). In multivariable analysis, overall R1-direct tumor margins, poor tumor differentiation, positive lymph node status, WHO performance status ≥1, maximum tumor size, and R1-direct posterior resection margin were all independently significantly associated with reduced overall and recurrence-free survival. Competing risks analysis showed that overall R1-direct positive resection margin status, positive lymph node status, WHO performance status 1, and R1-direct positive superior mesenteric/medial margin resection status were all significantly associated with local recurrence. Conclusions: R1-direct resections were associated with significantly reduced overall and recurrence-free survival following pancreatic cancer resection. Resection margin involvement was also associated with an increased risk for local recurrence." @default.
• W2765253206 created "2017-11-10" @default.
• W2765253206 creator A5002850467 @default.
• W2765253206 creator A5006284946 @default.
• W2765253206 creator A5008677072 @default.
• W2765253206 creator A5011077706 @default.
• W2765253206 creator A5013547689 @default.
• W2765253206 creator A5017526368 @default.
• W2765253206 creator A5020254111 @default.
• W2765253206 creator A5025100834 @default.
• W2765253206 creator A5025272654 @default.
• W2765253206 creator A5028548681 @default.
• W2765253206 creator A5029672876 @default.
• W2765253206 creator A5031145209 @default.
• W2765253206 creator A5031667128 @default.
• W2765253206 creator A5033965694 @default.
• W2765253206 creator A5035699979 @default.
• W2765253206 creator A5036032282 @default.
• W2765253206 creator A5038766805 @default.
• W2765253206 creator A5039983309 @default.
• W2765253206 creator A5044651904 @default.
• W2765253206 creator A5045168591 @default.
• W2765253206 creator A5046624072 @default.
• W2765253206 creator A5052825850 @default.
• W2765253206 creator A5053664013 @default.
• W2765253206 creator A5058208786 @default.
• W2765253206 creator A5068752367 @default.
• W2765253206 creator A5077826150 @default.
• W2765253206 creator A5079776850 @default.
• W2765253206 creator A5080423970 @default.
• W2765253206 creator A5080693514 @default.
• W2765253206 creator A5081306432 @default.
• W2765253206 creator A5082706093 @default.
• W2765253206 creator A5083073268 @default.
• W2765253206 date "2019-03-01" @default.
• W2765253206 modified "2023-10-14" @default.
• W2765253206 title "The Impact of Positive Resection Margins on Survival and Recurrence Following Resection and Adjuvant Chemotherapy for Pancreatic Ductal Adenocarcinoma" @default.
• W2765253206 cites W1965648796 @default.
• W2765253206 cites W1971141723 @default.
• W2765253206 cites W1974367374 @default.
• W2765253206 cites W1977103256 @default.
• W2765253206 cites W1977247044 @default.
• W2765253206 cites W1996430665 @default.
• W2765253206 cites W2007334557 @default.
• W2765253206 cites W2021064085 @default.
• W2765253206 cites W2029240267 @default.
• W2765253206 cites W2038981426 @default.
• W2765253206 cites W2047318784 @default.
• W2765253206 cites W2048038826 @default.
• W2765253206 cites W2049412596 @default.
• W2765253206 cites W2066185056 @default.
• W2765253206 cites W2079934168 @default.
• W2765253206 cites W2090803746 @default.
• W2765253206 cites W2111028538 @default.
• W2765253206 cites W2118078989 @default.
• W2765253206 cites W2129884672 @default.
• W2765253206 cites W2132799739 @default.
• W2765253206 cites W2137009991 @default.
• W2765253206 cites W2142635246 @default.
• W2765253206 cites W2152387274 @default.
• W2765253206 cites W2157590016 @default.
• W2765253206 cites W2168942492 @default.
• W2765253206 cites W2187668060 @default.
• W2765253206 cites W2343177790 @default.
• W2765253206 cites W2402879071 @default.
• W2765253206 cites W2417056901 @default.
• W2765253206 cites W2581973599 @default.
• W2765253206 cites W2592137794 @default.
• W2765253206 cites W2727784368 @default.
• W2765253206 cites W4211181525 @default.
• W2765253206 cites W4293241248 @default.
• W2765253206 cites W4384115643 @default.
• W2765253206 cites W980597899 @default.
• W2765253206 doi "https://doi.org/10.1097/sla.0000000000002557" @default.
• W2765253206 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29068800" @default.
• W2765253206 hasPublicationYear "2019" @default.
• W2765253206 type Work @default.
• W2765253206 sameAs 2765253206 @default.
• W2765253206 citedByCount "173" @default.
• W2765253206 countsByYear W27652532062018 @default.
• W2765253206 countsByYear W27652532062019 @default.
• W2765253206 countsByYear W27652532062020 @default.
• W2765253206 countsByYear W27652532062021 @default.
• W2765253206 countsByYear W27652532062022 @default.
• W2765253206 countsByYear W27652532062023 @default.
• W2765253206 crossrefType "journal-article" @default.
• W2765253206 hasAuthorship W2765253206A5002850467 @default.
• W2765253206 hasAuthorship W2765253206A5006284946 @default.
• W2765253206 hasAuthorship W2765253206A5008677072 @default.
• W2765253206 hasAuthorship W2765253206A5011077706 @default.
• W2765253206 hasAuthorship W2765253206A5013547689 @default.
• W2765253206 hasAuthorship W2765253206A5017526368 @default.
• W2765253206 hasAuthorship W2765253206A5020254111 @default.
• W2765253206 hasAuthorship W2765253206A5025100834 @default.
• W2765253206 hasAuthorship W2765253206A5025272654 @default.
• W2765253206 hasAuthorship W2765253206A5028548681 @default.
• W2765253206 hasAuthorship W2765253206A5029672876 @default.
• W2765253206 hasAuthorship W2765253206A5031145209 @default.

• next