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• W2765341618 abstract "Abstract Bioassays have been developed—since long before the availability of computers—to detect water, air, and soil toxicity. While today ethical considerations prevent more and more the use of vertebrate species as bioindicators, early bioassays employed fish and rodents to a large extent. Early bioassays have also been used to indicate insecticidal and antibacterial activity such as antibiotic substances excreted by Penicillium. Since maintaining a number of cultures for different bioassays in the laboratory may be difficult, a set of microbiotests have been developed which are provided as kits which contain the bioindicator organisms as spores, seeds, or dormant eggs or cysts. These tests have also been used to achieve comparability between different bioassays and to classify toxicity. Bioassays have been used to determine human health hazards. They allow not only to determine the type of tumor but also to quantify the effects of irradiation and anticancer drugs. Cyanobacterial and algal toxins in drinking water may directly result in poisoning of humans and animals or are concentrated in invertebrates and vertebrates by bioaccumulation. Hazards from these toxins have been determined using bioassays involving rodents and larger animals." @default.
• W2765341618 created "2017-11-10" @default.
• W2765341618 creator A5008376263 @default.
• W2765341618 date "2018-01-01" @default.
• W2765341618 modified "2023-10-16" @default.
• W2765341618 title "Historical development of bioassays" @default.
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• W2765341618 doi "https://doi.org/10.1016/b978-0-12-811861-0.00003-6" @default.
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