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- W2765435048 abstract "A facile strategy was developed to fabricate zinc (II) functionalized l-phenylalanine in situ grafted starch (Zn(II)@l-Phe-g-St). The structure of Zn(II)@l-Phe-g-St was proposed and well characterized, and the assays of antibacterial activity against typical bacteria (Bacillus subtilis and Escherichia coli) and cytotoxicity of Hela cell were focused on. Boc-l-phenylalanine was used to achieve l-Phe-g-St by in situ grafting onto starch through esterification reaction after removal of Boc. It was confirmed that around 71.02% of NH2 of l-Phe complexed with Zn(II) by σ-coordinate bonds and the coordination number of Zn(II) approximated to 2. Zn(II)@l-Phe-g-St exhibited a good antibacterial activity against both Bacillus subtilis and Escherichia coli with increasing its concentration, and a relatively more effective antibacterial activity against Bacillus subtilis than Escherichia coli. Furthermore, Zn(II)@l-Phe-g-St was found to be very low toxicity towards Hela cells especially at the concentration below 40 μg ml−1." @default.
- W2765435048 created "2017-11-10" @default.
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- W2765435048 date "2017-11-01" @default.
- W2765435048 modified "2023-10-18" @default.
- W2765435048 title "Fabrication of zinc (II) functionalized l -phenylalanine in situ grafted starch and its antibacterial activity and cytotoxicity" @default.
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- W2765435048 doi "https://doi.org/10.1016/j.jff.2017.09.015" @default.
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