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- W2765714897 abstract "Introduction Fractures in old age is a major health problem with considerable disability and mortality. Antipsychotic drugs (APs) have been associated with falls and fractures in elderly individuals. Methods The study performed was a retrospective analysis with 97 participants. Subjects were everyone over the age of 65 with fractures radiologically confirmed, hospitalized in Department of Orthopaedics and Traumatology “Sf. Ap. Andrei” Galaţi, România, in May 2017. The objective was to evaluate the association between APs and the risk of fractures in elderly persons. Results and discussion16 participants with confirmed fracture (16.50%) was associated with exposure to psychotropic medications. Those who took selective serotonin reuptake inhibitors (SSRIs), in particular, are linked to greater susceptibility to bone fractures: 10 out of 16 participants. Conclusion The mechanism leading to this increased risk is unclear. Clinical studies examining causality or mechanisms of the observed association between antipsychotic drug use and excess risk of fractures are needed. Confounding by indication, other drugs used or comorbidity cannot be excluded, this association is relevant for clinical practice because fractures and antipsychotic drug use are prevalent in vulnerable older individuals." @default.
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- W2765714897 date "2017-10-14" @default.
- W2765714897 modified "2023-09-26" @default.
- W2765714897 title "Psychotropic Drugs and the Risk of Fracture in Old Age" @default.
- W2765714897 doi "https://doi.org/10.11648/j.ajpn.s.2017050601.30" @default.
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