FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2765718643> ?p ?o ?g. }

• W2765718643 endingPage "1168" @default.
• W2765718643 startingPage "1159" @default.
• W2765718643 abstract "T-UCRs, a class of long non-coding RNAs that are transcribed from ultra-conserved regions (UCRs), might play an important role in development and diseases. However, the amount of T-UCRs that are conservatively expressed in the developing nervous systems of mice, monkeys and humans is still unknown. In this study, we screened the RNA sequence signals of 481 identified UCRs in an E14.5 mouse brain from the ENCODE database and found 76 UCRs that may be transcribed into T-UCRs. To verify the expression of these potential T-UCRs, we used an RT-PCR experiment and identified that 60 T-UCRs can be expressed in the E14.5 mouse brain. Furthermore, we detected the expression conservation of 76 potential T-UCRs in two comparisons: postnatal day 0 brains of a mouse and a rhesus monkey and neural stem cells of mouse and human by RT-PCR experimentation. It was found that up to 65% of these T-UCRs were expressed in mouse, rhesus monkey and human nervous systems. Next, by testing the spatiotemporal expression pattern of these T-UCRs expressed in mouse, rhesus monkey and human nervous systems, we found that approximately 30% of the T-UCRs showed a relatively high and dynamical expression during mouse brain development. Finally, through biological process and molecular function gene ontology analysis of the host genes of intronic or exonic-antisense T-UCRs, it was discovered that most of the genes were involved in RNA splicing or RNA binding. These results suggest that T-UCRs are likely to participate in nervous system development through RNA processing." @default.
• W2765718643 created "2017-11-10" @default.
• W2765718643 creator A5002069152 @default.
• W2765718643 creator A5010319430 @default.
• W2765718643 creator A5017007019 @default.
• W2765718643 creator A5017947172 @default.
• W2765718643 creator A5019309501 @default.
• W2765718643 creator A5028200147 @default.
• W2765718643 creator A5030135901 @default.
• W2765718643 creator A5036055671 @default.
• W2765718643 creator A5050213589 @default.
• W2765718643 creator A5063933498 @default.
• W2765718643 creator A5076943977 @default.
• W2765718643 creator A5077484550 @default.
• W2765718643 creator A5080390336 @default.
• W2765718643 date "2017-12-01" @default.
• W2765718643 modified "2023-10-16" @default.
• W2765718643 title "Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system" @default.
• W2765718643 cites W1636792118 @default.
• W2765718643 cites W1996394817 @default.
• W2765718643 cites W1998745514 @default.
• W2765718643 cites W2009300653 @default.
• W2765718643 cites W2015105137 @default.
• W2765718643 cites W2019525579 @default.
• W2765718643 cites W2022472106 @default.
• W2765718643 cites W2037385985 @default.
• W2765718643 cites W2042720937 @default.
• W2765718643 cites W2046689211 @default.
• W2765718643 cites W2057143081 @default.
• W2765718643 cites W2062478949 @default.
• W2765718643 cites W2066261076 @default.
• W2765718643 cites W2067374373 @default.
• W2765718643 cites W2067410483 @default.
• W2765718643 cites W2074284100 @default.
• W2765718643 cites W2092133261 @default.
• W2765718643 cites W2098993201 @default.
• W2765718643 cites W2100990361 @default.
• W2765718643 cites W2101517749 @default.
• W2765718643 cites W2103224959 @default.
• W2765718643 cites W2116790427 @default.
• W2765718643 cites W2123584320 @default.
• W2765718643 cites W2141541691 @default.
• W2765718643 cites W2141831115 @default.
• W2765718643 cites W2158217645 @default.
• W2765718643 cites W2159274404 @default.
• W2765718643 cites W2171631429 @default.
• W2765718643 cites W2189655283 @default.
• W2765718643 cites W2198153867 @default.
• W2765718643 cites W2289875342 @default.
• W2765718643 cites W2326761376 @default.
• W2765718643 cites W2327961102 @default.
• W2765718643 cites W2462520477 @default.
• W2765718643 cites W2473676619 @default.
• W2765718643 cites W2521108230 @default.
• W2765718643 cites W2528536314 @default.
• W2765718643 cites W2624483516 @default.
• W2765718643 cites W2742722242 @default.
• W2765718643 doi "https://doi.org/10.1016/j.bbagrm.2017.10.002" @default.
• W2765718643 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29055695" @default.
• W2765718643 hasPublicationYear "2017" @default.
• W2765718643 type Work @default.
• W2765718643 sameAs 2765718643 @default.
• W2765718643 citedByCount "12" @default.
• W2765718643 countsByYear W27657186432018 @default.
• W2765718643 countsByYear W27657186432019 @default.
• W2765718643 countsByYear W27657186432020 @default.
• W2765718643 countsByYear W27657186432021 @default.
• W2765718643 countsByYear W27657186432023 @default.
• W2765718643 crossrefType "journal-article" @default.
• W2765718643 hasAuthorship W2765718643A5002069152 @default.
• W2765718643 hasAuthorship W2765718643A5010319430 @default.
• W2765718643 hasAuthorship W2765718643A5017007019 @default.
• W2765718643 hasAuthorship W2765718643A5017947172 @default.
• W2765718643 hasAuthorship W2765718643A5019309501 @default.
• W2765718643 hasAuthorship W2765718643A5028200147 @default.
• W2765718643 hasAuthorship W2765718643A5030135901 @default.
• W2765718643 hasAuthorship W2765718643A5036055671 @default.
• W2765718643 hasAuthorship W2765718643A5050213589 @default.
• W2765718643 hasAuthorship W2765718643A5063933498 @default.
• W2765718643 hasAuthorship W2765718643A5076943977 @default.
• W2765718643 hasAuthorship W2765718643A5077484550 @default.
• W2765718643 hasAuthorship W2765718643A5080390336 @default.
• W2765718643 hasConcept C104317684 @default.
• W2765718643 hasConcept C105580179 @default.
• W2765718643 hasConcept C150194340 @default.
• W2765718643 hasConcept C167625842 @default.
• W2765718643 hasConcept C194583182 @default.
• W2765718643 hasConcept C194993378 @default.
• W2765718643 hasConcept C199216141 @default.
• W2765718643 hasConcept C54355233 @default.
• W2765718643 hasConcept C54458228 @default.
• W2765718643 hasConcept C66746571 @default.
• W2765718643 hasConcept C67705224 @default.
• W2765718643 hasConcept C70721500 @default.
• W2765718643 hasConcept C86803240 @default.
• W2765718643 hasConceptScore W2765718643C104317684 @default.
• W2765718643 hasConceptScore W2765718643C105580179 @default.
• W2765718643 hasConceptScore W2765718643C150194340 @default.

• next