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- W2765727312 abstract "Polycystic ovary syndrome (PCOS) represents one of the most common endocrine abnormalities within the reproductive system and consists mainly of menstrual irregularities, signs of androgen excess, and subfertility. Women with PCOS have frequently a cluster of cardiometabolic risk factors including abdominal obesity, dyslipidemia, hypertension, and abnormal glucose metabolism ranging from insulin resistance to overt diabetes. These women, furthermore, have evidence of accelerated subclinical arterial disease, manifesting as subclinical atherosclerosis, increased arterial stiffness, or endothelial dysfunction. Despite an increasing number of reports on a positive association between PCOS and cardiovascular outcomes, there is as yet inconclusive evidence concerning the incidence of cardiovascular events in this population. Although the endocrine profile of women with PCOS persists after menopause, the difficulty to demonstrate an independent effect of PCOS on cardiovascular morbidity and mortality lies mainly on the fact that as a woman grows older the detrimental effect of postmenopausal estrogen deficiency, obesity, and diabetes on the cardiovascular system may override the contribution of PCOS." @default.
- W2765727312 created "2017-11-10" @default.
- W2765727312 creator A5084991470 @default.
- W2765727312 date "2015-01-01" @default.
- W2765727312 modified "2023-10-15" @default.
- W2765727312 title "Non-Hemodynamic Components of EVA" @default.
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- W2765727312 doi "https://doi.org/10.1016/b978-0-12-801387-8.00018-1" @default.
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