FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2765745974> ?p ?o ?g. }

• W2765745974 endingPage "747" @default.
• W2765745974 startingPage "741" @default.
• W2765745974 abstract "Dialyzable leukocyte extracts (DLEs) contain molecules smaller than 10 kDa with biological activity in receptor organisms. Primarily, they participate in the regulation of the Th1 immune response, which is essential for the control of several intracellular infections, such as toxoplasmosis. This disease is associated with congenital infection, encephalitis or systemic infections in immunocompromised individuals. The clinical course of this infection fundamentally depends on a well-regulated immune response and timely treatment with the appropriate drugs.The aim of this study was to evaluate the effect of treatment with a leukocyte extract, derived from crocodile lymphoid tissue, on the histopathology and brain parasite load in NIH mice that had been infected with cysts of Toxoplasma gondii (ME-49 strain).The treatment was applied during the acute and chronic stages of the infection. Histopathological changes were evaluated in the ileum, liver and spleen at one, four and eight weeks after infection and in the brain at week 8. The parasite load was evaluated by counting the cysts of T. gondii found in the brain.Compared to the control mouse group, the mice infected with T. gondii and under treatment with DLE showed less tissue damage, mainly at the intestinal, splenic and hepatic levels. In addition, a greater percentage of survival was observed, and there was a considerable reduction in the parasite load in the brain.The results suggest that DLE derived from crocodile is a potential adjunctive therapy in the conventional treatment of toxoplasmosis." @default.
• W2765745974 created "2017-11-10" @default.
• W2765745974 creator A5013585861 @default.
• W2765745974 creator A5038730190 @default.
• W2765745974 creator A5069338249 @default.
• W2765745974 creator A5091868022 @default.
• W2765745974 date "2017-11-01" @default.
• W2765745974 modified "2023-10-06" @default.
• W2765745974 title "Histopathology of murine toxoplasmosis under treatment with dialyzable leukocyte extract" @default.
• W2765745974 cites W111869655 @default.
• W2765745974 cites W1975569298 @default.
• W2765745974 cites W1980791912 @default.
• W2765745974 cites W1985466331 @default.
• W2765745974 cites W1989639401 @default.
• W2765745974 cites W2019473457 @default.
• W2765745974 cites W2022783631 @default.
• W2765745974 cites W2023245937 @default.
• W2765745974 cites W2027435977 @default.
• W2765745974 cites W2036326466 @default.
• W2765745974 cites W2037655228 @default.
• W2765745974 cites W2040562810 @default.
• W2765745974 cites W2055769360 @default.
• W2765745974 cites W2057942881 @default.
• W2765745974 cites W2071601749 @default.
• W2765745974 cites W2081316389 @default.
• W2765745974 cites W2090143372 @default.
• W2765745974 cites W2097659338 @default.
• W2765745974 cites W2105410310 @default.
• W2765745974 cites W2116551282 @default.
• W2765745974 cites W2116556306 @default.
• W2765745974 cites W2128139999 @default.
• W2765745974 cites W2129476427 @default.
• W2765745974 cites W2131416725 @default.
• W2765745974 cites W2138334533 @default.
• W2765745974 cites W2144509281 @default.
• W2765745974 cites W2173768724 @default.
• W2765745974 cites W2414892197 @default.
• W2765745974 cites W98163506 @default.
• W2765745974 doi "https://doi.org/10.1590/0074-02760170045" @default.
• W2765745974 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5661896" @default.
• W2765745974 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29091133" @default.
• W2765745974 hasPublicationYear "2017" @default.
• W2765745974 type Work @default.
• W2765745974 sameAs 2765745974 @default.
• W2765745974 citedByCount "19" @default.
• W2765745974 countsByYear W27657459742018 @default.
• W2765745974 countsByYear W27657459742019 @default.
• W2765745974 countsByYear W27657459742020 @default.
• W2765745974 countsByYear W27657459742021 @default.
• W2765745974 countsByYear W27657459742022 @default.
• W2765745974 countsByYear W27657459742023 @default.
• W2765745974 crossrefType "journal-article" @default.
• W2765745974 hasAuthorship W2765745974A5013585861 @default.
• W2765745974 hasAuthorship W2765745974A5038730190 @default.
• W2765745974 hasAuthorship W2765745974A5069338249 @default.
• W2765745974 hasAuthorship W2765745974A5091868022 @default.
• W2765745974 hasBestOaLocation W27657459741 @default.
• W2765745974 hasConcept C136764020 @default.
• W2765745974 hasConcept C142724271 @default.
• W2765745974 hasConcept C159654299 @default.
• W2765745974 hasConcept C203014093 @default.
• W2765745974 hasConcept C2522874641 @default.
• W2765745974 hasConcept C2775993617 @default.
• W2765745974 hasConcept C2778062946 @default.
• W2765745974 hasConcept C2778128430 @default.
• W2765745974 hasConcept C2780931953 @default.
• W2765745974 hasConcept C41008148 @default.
• W2765745974 hasConcept C544855455 @default.
• W2765745974 hasConcept C71924100 @default.
• W2765745974 hasConcept C71928629 @default.
• W2765745974 hasConcept C83455156 @default.
• W2765745974 hasConcept C86803240 @default.
• W2765745974 hasConcept C8891405 @default.
• W2765745974 hasConceptScore W2765745974C136764020 @default.
• W2765745974 hasConceptScore W2765745974C142724271 @default.
• W2765745974 hasConceptScore W2765745974C159654299 @default.
• W2765745974 hasConceptScore W2765745974C203014093 @default.
• W2765745974 hasConceptScore W2765745974C2522874641 @default.
• W2765745974 hasConceptScore W2765745974C2775993617 @default.
• W2765745974 hasConceptScore W2765745974C2778062946 @default.
• W2765745974 hasConceptScore W2765745974C2778128430 @default.
• W2765745974 hasConceptScore W2765745974C2780931953 @default.
• W2765745974 hasConceptScore W2765745974C41008148 @default.
• W2765745974 hasConceptScore W2765745974C544855455 @default.
• W2765745974 hasConceptScore W2765745974C71924100 @default.
• W2765745974 hasConceptScore W2765745974C71928629 @default.
• W2765745974 hasConceptScore W2765745974C83455156 @default.
• W2765745974 hasConceptScore W2765745974C86803240 @default.
• W2765745974 hasConceptScore W2765745974C8891405 @default.
• W2765745974 hasIssue "11" @default.
• W2765745974 hasLocation W27657459741 @default.
• W2765745974 hasLocation W27657459742 @default.
• W2765745974 hasLocation W27657459743 @default.
• W2765745974 hasLocation W27657459744 @default.
• W2765745974 hasLocation W27657459745 @default.
• W2765745974 hasOpenAccess W2765745974 @default.
• W2765745974 hasPrimaryLocation W27657459741 @default.
• W2765745974 hasRelatedWork W1975098398 @default.

• next