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- W2765785007 abstract "Background: Clinical cancer treatment and therapy have been gradually improved by experimental and clinical advancements worldwide, especially after the advent of different types of individualized cancer therapy (ICT). Objective: Despite the longest history of anticancer drug sensitivity testing (DST) among ICT, its therapeutic applications for clinical cancer trials need to be updated. Methods: DST techniques are widely diversified and improved a great deal, but they have not been matured to cure all cancer patients in clinics. Results: The retrospection and panorama of historic and evolutionary developments of DST including clinical relevance, advantageous, technical cautions, limitations of varied models and methodologies at present stage are addressed. Conclusion: Future directions and novel ideas must be established. Keywords: Anticancer drugs, cancer stem cell, clinical cancer therapy, drug combinations, drug sensitivity test, individualized cancer therapy, neoplasm metastasis." @default.
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- W2765785007 date "2015-08-25" @default.
- W2765785007 modified "2023-10-16" @default.
- W2765785007 title "Anticancer Drug Sensitivity Testing, a Historical Review and Future Perspectives" @default.
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- W2765785007 doi "https://doi.org/10.2174/157488551001150825100450" @default.
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