Matches in SemOpenAlex for { <https://semopenalex.org/work/W2765795497> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2765795497 abstract "Diet may be an important modifiable determinant of cognitive decline and dementia. However, the effect of diet on brain structure and its underlying pathways towards dementia still remain unclear. In 4285 non-demented participants from the population-based Rotterdam Study, (56.6% women, mean age: 65.8 (SD : 10.8)), we assessed diet using the Food Frequency Questionnaire. Additionally, these participants underwent brain MRI on which automated segmentation and quantification of brain tissue volumes was performed (total brain volume, grey matter volume, white matter volume, hippocampal volume). Also, we evaluated the presence of cerebral small vessel disease (white matter hyperintensity volume, lacunar infarcts and cerebral microbleeds). Linear- and logistic regression models were used to investigate the association of adherence to the dietary guidelines with the specific brain parameters. All analyses were adjusted for age, sex, years of education and intracranial volume. We found that better adherence to overall diet is related to larger total brain volume [standardized difference per 1-SD increase in diet score: .019 (95% CI: .011 - .026)], grey matter volume (difference = .013, CI: .002 - .024), white matter volume (difference = .017, CI: .005 - .028), and hippocampal volume (difference = .019, CI: .006 - .032) . When investigating specific food groups in relation to brain structure, we found that the consumption of fruit was most prominently associated with larger total brain volume, white matter volume, and hippocampal volume, whereas the consumption of dairy was related to larger grey matter volume. For markers of cerebral small vessel disease we found that vegetable consumption was associated with a lower presence of lacunar infarcts (OR = 0.63; CI 95%: .45 - .86). High(er) adherence to overall diet is related to larger volumes in different brain regions, implying that following a healthy diet is beneficiary for the brain. Especially the consumption of fruit and vegetables is related to larger volumes is specific brain regions." @default.
- W2765795497 created "2017-11-10" @default.
- W2765795497 creator A5006966796 @default.
- W2765795497 creator A5022417082 @default.
- W2765795497 creator A5028850171 @default.
- W2765795497 creator A5036303967 @default.
- W2765795497 creator A5056326170 @default.
- W2765795497 creator A5078190652 @default.
- W2765795497 date "2017-07-01" @default.
- W2765795497 modified "2023-09-27" @default.
- W2765795497 title "[P4-338]: DIETARY PATTERNS AND BRAIN STRUCTURE IN DEMENTIA-FREE INDIVIDUALS: THE ROTTERDAM STUDY" @default.
- W2765795497 doi "https://doi.org/10.1016/j.jalz.2017.06.2208" @default.
- W2765795497 hasPublicationYear "2017" @default.
- W2765795497 type Work @default.
- W2765795497 sameAs 2765795497 @default.
- W2765795497 citedByCount "0" @default.
- W2765795497 crossrefType "journal-article" @default.
- W2765795497 hasAuthorship W2765795497A5006966796 @default.
- W2765795497 hasAuthorship W2765795497A5022417082 @default.
- W2765795497 hasAuthorship W2765795497A5028850171 @default.
- W2765795497 hasAuthorship W2765795497A5036303967 @default.
- W2765795497 hasAuthorship W2765795497A5056326170 @default.
- W2765795497 hasAuthorship W2765795497A5078190652 @default.
- W2765795497 hasBestOaLocation W27657954971 @default.
- W2765795497 hasConcept C126322002 @default.
- W2765795497 hasConcept C126838900 @default.
- W2765795497 hasConcept C143409427 @default.
- W2765795497 hasConcept C146638467 @default.
- W2765795497 hasConcept C148762608 @default.
- W2765795497 hasConcept C151956035 @default.
- W2765795497 hasConcept C204452808 @default.
- W2765795497 hasConcept C2778013878 @default.
- W2765795497 hasConcept C2779134260 @default.
- W2765795497 hasConcept C2779483572 @default.
- W2765795497 hasConcept C2781172350 @default.
- W2765795497 hasConcept C2781192897 @default.
- W2765795497 hasConcept C2908647359 @default.
- W2765795497 hasConcept C42407357 @default.
- W2765795497 hasConcept C65835030 @default.
- W2765795497 hasConcept C71924100 @default.
- W2765795497 hasConcept C99454951 @default.
- W2765795497 hasConceptScore W2765795497C126322002 @default.
- W2765795497 hasConceptScore W2765795497C126838900 @default.
- W2765795497 hasConceptScore W2765795497C143409427 @default.
- W2765795497 hasConceptScore W2765795497C146638467 @default.
- W2765795497 hasConceptScore W2765795497C148762608 @default.
- W2765795497 hasConceptScore W2765795497C151956035 @default.
- W2765795497 hasConceptScore W2765795497C204452808 @default.
- W2765795497 hasConceptScore W2765795497C2778013878 @default.
- W2765795497 hasConceptScore W2765795497C2779134260 @default.
- W2765795497 hasConceptScore W2765795497C2779483572 @default.
- W2765795497 hasConceptScore W2765795497C2781172350 @default.
- W2765795497 hasConceptScore W2765795497C2781192897 @default.
- W2765795497 hasConceptScore W2765795497C2908647359 @default.
- W2765795497 hasConceptScore W2765795497C42407357 @default.
- W2765795497 hasConceptScore W2765795497C65835030 @default.
- W2765795497 hasConceptScore W2765795497C71924100 @default.
- W2765795497 hasConceptScore W2765795497C99454951 @default.
- W2765795497 hasIssue "7S_Part_29" @default.
- W2765795497 hasLocation W27657954971 @default.
- W2765795497 hasOpenAccess W2765795497 @default.
- W2765795497 hasPrimaryLocation W27657954971 @default.
- W2765795497 hasRelatedWork W2045661260 @default.
- W2765795497 hasRelatedWork W2163980871 @default.
- W2765795497 hasRelatedWork W220777649 @default.
- W2765795497 hasRelatedWork W2291469492 @default.
- W2765795497 hasRelatedWork W2765795497 @default.
- W2765795497 hasRelatedWork W2782036709 @default.
- W2765795497 hasRelatedWork W2978765218 @default.
- W2765795497 hasRelatedWork W3115446597 @default.
- W2765795497 hasRelatedWork W4212849209 @default.
- W2765795497 hasRelatedWork W4283700902 @default.
- W2765795497 hasVolume "13" @default.
- W2765795497 isParatext "false" @default.
- W2765795497 isRetracted "false" @default.
- W2765795497 magId "2765795497" @default.
- W2765795497 workType "article" @default.