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- W2765796376 abstract "Iodine may have originally emerged as a substrate for thyroid hormone production due to its role as an indicator of resource availability in the ecosystem and the corresponding need to modulate growth, reproduction, metabolic rate and lifespan. While marine algae may use iodine for self-defense, herbivores and higher-order predators further down the ecosystem may use dietary iodine as a surrogate sensor for overall availability of ecosystem resources. Numerous nutritional factors influence the production of thyroid hormone among the most important is dietary intake of iodine. The prehistoric link of iodine to thyroid function may have become less adaptive due to evolutionary displacement. While dietary iodine intake may have once served as a useful proxy for nutritional availability, this linkage has apparently become decoupled in the modern era. Independent from any association with resource availability, iodine deficiency may arise from decline in both soil reservoirs and the terrestrial ecosystem, which is caused due to both glaciation and the leaching effects of groundwater. Iodine or iodine modulators may also have potential uses as modulators of the endocrine axis, thus treating diseases such as syndrome X, infertility, and growth retardation." @default.
- W2765796376 created "2017-11-10" @default.
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- W2765796376 date "2009-01-01" @default.
- W2765796376 modified "2023-10-16" @default.
- W2765796376 title "Iodine in the Ecosystem" @default.
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- W2765796376 doi "https://doi.org/10.1016/b978-0-12-374135-6.00012-1" @default.
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