FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2765820281> ?p ?o ?g. }

• W2765820281 endingPage "1889" @default.
• W2765820281 startingPage "1889" @default.
• W2765820281 abstract "<ns4:p><ns4:bold><ns4:italic>Background:</ns4:italic></ns4:bold> It has been shown repeatedly that mast cells can promote or prevent cancer development and growth. If development and/or progression of a solid cancer is substantially influenced by mast cell activity, the frequencies of occurrence of solid cancers in patients with primary mast cells disorders would be expected to differ from the corresponding prevalence data in the general population. In fact, a recent study demonstrated that patients with systemic mastocytosis (i.e., a rare neoplastic variant of the primary mast cell activation disease) have increased risk for solid cancers, in particular melanoma and non-melanoma skin cancers. The aim of the present study is to examine whether the risk of solid cancer is increased in systemic mast cell activation syndrome (MCAS), the common systemic variant of mast cell activation disease.</ns4:p><ns4:p> <ns4:bold><ns4:italic>Methods:</ns4:italic></ns4:bold> In the present descriptive study, we have analysed a large (n=828) patient group with MCAS, consisting of cohorts from Germany and the USA, for occurrence of solid forms of cancer and compared the frequencies of the different cancers with corresponding prevalence data for German and U.S. general populations.</ns4:p><ns4:p> <ns4:bold><ns4:italic>Results:</ns4:italic></ns4:bold> Sixty-eight of the 828 MCAS patients (46 female, 22 male) had developed a solid tumor before the diagnosis of MCAS was made. Comparison of the frequencies of the malignancies in the MCAS patients with their prevalence in the general population revealed a significantly increased prevalence for melanoma and cancers of the breast, cervix uteri, ovary, lung, and thyroid in MCAS patients.</ns4:p><ns4:p> <ns4:bold><ns4:italic>Conclusions:</ns4:italic></ns4:bold> Our data support the view that mast cells may promote development of certain malignant tumors. These findings indicate a need for increased surveillance of certain types of cancer in MCAS patients irrespective of its individual clinical presentation.</ns4:p>" @default.
• W2765820281 created "2017-11-10" @default.
• W2765820281 creator A5001100810 @default.
• W2765820281 creator A5007421553 @default.
• W2765820281 creator A5029602388 @default.
• W2765820281 creator A5057055893 @default.
• W2765820281 creator A5075629668 @default.
• W2765820281 date "2017-10-26" @default.
• W2765820281 modified "2023-09-30" @default.
• W2765820281 title "Risk of solid cancer in patients with mast cell activation syndrome: Results from Germany and USA" @default.
• W2765820281 cites W1606413143 @default.
• W2765820281 cites W1966291047 @default.
• W2765820281 cites W1970343716 @default.
• W2765820281 cites W1976112057 @default.
• W2765820281 cites W1976229861 @default.
• W2765820281 cites W1976472116 @default.
• W2765820281 cites W1978899914 @default.
• W2765820281 cites W1989250714 @default.
• W2765820281 cites W1992476962 @default.
• W2765820281 cites W1994726551 @default.
• W2765820281 cites W2003100495 @default.
• W2765820281 cites W2003277993 @default.
• W2765820281 cites W2003904711 @default.
• W2765820281 cites W2007288508 @default.
• W2765820281 cites W2012268802 @default.
• W2765820281 cites W2021616811 @default.
• W2765820281 cites W2022199206 @default.
• W2765820281 cites W2035580331 @default.
• W2765820281 cites W2041669185 @default.
• W2765820281 cites W2046214587 @default.
• W2765820281 cites W2049382623 @default.
• W2765820281 cites W2055287171 @default.
• W2765820281 cites W2063717508 @default.
• W2765820281 cites W2069998039 @default.
• W2765820281 cites W2073846703 @default.
• W2765820281 cites W2084834249 @default.
• W2765820281 cites W2085976481 @default.
• W2765820281 cites W2086437357 @default.
• W2765820281 cites W2092978522 @default.
• W2765820281 cites W2094906508 @default.
• W2765820281 cites W2100272405 @default.
• W2765820281 cites W2104540105 @default.
• W2765820281 cites W2106763728 @default.
• W2765820281 cites W2117188898 @default.
• W2765820281 cites W2130317128 @default.
• W2765820281 cites W2130898095 @default.
• W2765820281 cites W2134632882 @default.
• W2765820281 cites W2137564162 @default.
• W2765820281 cites W2145248653 @default.
• W2765820281 cites W2150657589 @default.
• W2765820281 cites W2157729118 @default.
• W2765820281 cites W2304418899 @default.
• W2765820281 cites W2402139799 @default.
• W2765820281 cites W2494564964 @default.
• W2765820281 cites W2500186649 @default.
• W2765820281 doi "https://doi.org/10.12688/f1000research.12730.1" @default.
• W2765820281 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5710302" @default.
• W2765820281 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29225779" @default.
• W2765820281 hasPublicationYear "2017" @default.
• W2765820281 type Work @default.
• W2765820281 sameAs 2765820281 @default.
• W2765820281 citedByCount "32" @default.
• W2765820281 countsByYear W27658202812018 @default.
• W2765820281 countsByYear W27658202812019 @default.
• W2765820281 countsByYear W27658202812020 @default.
• W2765820281 countsByYear W27658202812021 @default.
• W2765820281 countsByYear W27658202812022 @default.
• W2765820281 countsByYear W27658202812023 @default.
• W2765820281 crossrefType "journal-article" @default.
• W2765820281 hasAuthorship W2765820281A5001100810 @default.
• W2765820281 hasAuthorship W2765820281A5007421553 @default.
• W2765820281 hasAuthorship W2765820281A5029602388 @default.
• W2765820281 hasAuthorship W2765820281A5057055893 @default.
• W2765820281 hasAuthorship W2765820281A5075629668 @default.
• W2765820281 hasBestOaLocation W27658202811 @default.
• W2765820281 hasConcept C121608353 @default.
• W2765820281 hasConcept C126322002 @default.
• W2765820281 hasConcept C142724271 @default.
• W2765820281 hasConcept C2779134260 @default.
• W2765820281 hasConcept C2908647359 @default.
• W2765820281 hasConcept C71924100 @default.
• W2765820281 hasConcept C86803240 @default.
• W2765820281 hasConcept C99454951 @default.
• W2765820281 hasConceptScore W2765820281C121608353 @default.
• W2765820281 hasConceptScore W2765820281C126322002 @default.
• W2765820281 hasConceptScore W2765820281C142724271 @default.
• W2765820281 hasConceptScore W2765820281C2779134260 @default.
• W2765820281 hasConceptScore W2765820281C2908647359 @default.
• W2765820281 hasConceptScore W2765820281C71924100 @default.
• W2765820281 hasConceptScore W2765820281C86803240 @default.
• W2765820281 hasConceptScore W2765820281C99454951 @default.
• W2765820281 hasFunder F4320307634 @default.
• W2765820281 hasLocation W27658202811 @default.
• W2765820281 hasLocation W27658202812 @default.
• W2765820281 hasLocation W27658202813 @default.
• W2765820281 hasLocation W27658202814 @default.
• W2765820281 hasOpenAccess W2765820281 @default.
• W2765820281 hasPrimaryLocation W27658202811 @default.

• next