FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2765942081> ?p ?o ?g. }

• W2765942081 endingPage "151" @default.
• W2765942081 startingPage "145" @default.
• W2765942081 abstract "Summary Background Human melanocytes express Toll‐like receptor 4 ( TLR 4), which regulates ultraviolet ( UV )‐induced cutaneous immunosuppression in Langerhans cells. Lipopolysaccharide ( LPS ) stimulation increases melanocyte pigmentation and TLR 4 expression, while inducing local innate inflammatory responses. Aims We investigated whether UV radiation induces TLR 4 expression in neonatal human melanocytes ( NHM s) and how this affects the immune system. Methods We cultured NHM s with LPS treatment or with one‐time or repeated UVA or UVB exposure, and investigated and compared the effects on TLR 4 expression, melanin contents, and cytokine production. Results NHM s in the resting state did not express TLR 4. LPS stimulation induced TLR 4 expression and increased pigmentation. TLR 4 expression was not detected after single‐dose UVA or UVB treatment, but pigmentation increased. Repeated UV treatment induced TLR 4 expression and increased pigmentation. LPS stimulation and repeated UV treatment increased IL ‐6 secretion, and repeated UVB treatment increased IL ‐10 secretion. Conclusion These results suggest that human melanocytes may actively participate in UV ‐induced immune modulation." @default.
• W2765942081 created "2017-11-10" @default.
• W2765942081 creator A5004260448 @default.
• W2765942081 creator A5048055137 @default.
• W2765942081 creator A5054225543 @default.
• W2765942081 creator A5082907572 @default.
• W2765942081 date "2017-12-05" @default.
• W2765942081 modified "2023-10-12" @default.
• W2765942081 title "Repeated ultraviolet irradiation induces the expression of Toll‐like receptor 4, <scp>IL</scp>‐6, and <scp>IL</scp>‐10 in neonatal human melanocytes" @default.
• W2765942081 cites W1508034450 @default.
• W2765942081 cites W1515725948 @default.
• W2765942081 cites W1562209821 @default.
• W2765942081 cites W1809966404 @default.
• W2765942081 cites W1881237907 @default.
• W2765942081 cites W1967368116 @default.
• W2765942081 cites W1974961885 @default.
• W2765942081 cites W1976668997 @default.
• W2765942081 cites W1979872069 @default.
• W2765942081 cites W2010249931 @default.
• W2765942081 cites W2019183195 @default.
• W2765942081 cites W2035065233 @default.
• W2765942081 cites W2043172109 @default.
• W2765942081 cites W2060600354 @default.
• W2765942081 cites W2061867074 @default.
• W2765942081 cites W2070542693 @default.
• W2765942081 cites W2074212023 @default.
• W2765942081 cites W2082821194 @default.
• W2765942081 cites W2083829960 @default.
• W2765942081 cites W2092469426 @default.
• W2765942081 cites W2108578752 @default.
• W2765942081 cites W2111034338 @default.
• W2765942081 cites W2144346426 @default.
• W2765942081 cites W2166554253 @default.
• W2765942081 cites W2167886213 @default.
• W2765942081 cites W2170043916 @default.
• W2765942081 doi "https://doi.org/10.1111/phpp.12359" @default.
• W2765942081 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29063638" @default.
• W2765942081 hasPublicationYear "2017" @default.
• W2765942081 type Work @default.
• W2765942081 sameAs 2765942081 @default.
• W2765942081 citedByCount "9" @default.
• W2765942081 countsByYear W27659420812019 @default.
• W2765942081 countsByYear W27659420812020 @default.
• W2765942081 countsByYear W27659420812021 @default.
• W2765942081 countsByYear W27659420812022 @default.
• W2765942081 crossrefType "journal-article" @default.
• W2765942081 hasAuthorship W2765942081A5004260448 @default.
• W2765942081 hasAuthorship W2765942081A5048055137 @default.
• W2765942081 hasAuthorship W2765942081A5054225543 @default.
• W2765942081 hasAuthorship W2765942081A5082907572 @default.
• W2765942081 hasConcept C126322002 @default.
• W2765942081 hasConcept C134018914 @default.
• W2765942081 hasConcept C136449434 @default.
• W2765942081 hasConcept C170493617 @default.
• W2765942081 hasConcept C203014093 @default.
• W2765942081 hasConcept C24998067 @default.
• W2765942081 hasConcept C2776709828 @default.
• W2765942081 hasConcept C2776914184 @default.
• W2765942081 hasConcept C2777459323 @default.
• W2765942081 hasConcept C2777658100 @default.
• W2765942081 hasConcept C2778690821 @default.
• W2765942081 hasConcept C2778754761 @default.
• W2765942081 hasConcept C2779769559 @default.
• W2765942081 hasConcept C49039625 @default.
• W2765942081 hasConcept C502942594 @default.
• W2765942081 hasConcept C54355233 @default.
• W2765942081 hasConcept C71924100 @default.
• W2765942081 hasConcept C86803240 @default.
• W2765942081 hasConcept C8891405 @default.
• W2765942081 hasConceptScore W2765942081C126322002 @default.
• W2765942081 hasConceptScore W2765942081C134018914 @default.
• W2765942081 hasConceptScore W2765942081C136449434 @default.
• W2765942081 hasConceptScore W2765942081C170493617 @default.
• W2765942081 hasConceptScore W2765942081C203014093 @default.
• W2765942081 hasConceptScore W2765942081C24998067 @default.
• W2765942081 hasConceptScore W2765942081C2776709828 @default.
• W2765942081 hasConceptScore W2765942081C2776914184 @default.
• W2765942081 hasConceptScore W2765942081C2777459323 @default.
• W2765942081 hasConceptScore W2765942081C2777658100 @default.
• W2765942081 hasConceptScore W2765942081C2778690821 @default.
• W2765942081 hasConceptScore W2765942081C2778754761 @default.
• W2765942081 hasConceptScore W2765942081C2779769559 @default.
• W2765942081 hasConceptScore W2765942081C49039625 @default.
• W2765942081 hasConceptScore W2765942081C502942594 @default.
• W2765942081 hasConceptScore W2765942081C54355233 @default.
• W2765942081 hasConceptScore W2765942081C71924100 @default.
• W2765942081 hasConceptScore W2765942081C86803240 @default.
• W2765942081 hasConceptScore W2765942081C8891405 @default.
• W2765942081 hasIssue "2" @default.
• W2765942081 hasLocation W27659420811 @default.
• W2765942081 hasLocation W27659420812 @default.
• W2765942081 hasOpenAccess W2765942081 @default.
• W2765942081 hasPrimaryLocation W27659420811 @default.
• W2765942081 hasRelatedWork W1938846279 @default.
• W2765942081 hasRelatedWork W1967465054 @default.
• W2765942081 hasRelatedWork W2036495427 @default.
• W2765942081 hasRelatedWork W2074961267 @default.
• W2765942081 hasRelatedWork W2087562989 @default.

• next