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- W2765956218 abstract "In this work, a new selective and simple fluorescence probe based on polyethylenimine(PEI) functionalized carbon dots (PEI-CDs) for fast determination of 6-thioguanine (6-TG) was developed. We successfully prepared the highly fluorescent PEI-CDs by hydrothermal method, and completed the synthesis and modification processes in one step. The fluorescence quantum yield (QY) of the as-synthesized CDs was 38% and higher than that of most previous reports (5–30%). The fluorescence intensity of PEI-CDs decreased obviously with gradually increased concentration of 6-TG. The interference substances caused a negligible effect on the fluorescence intensity of the (PEI-CDs)-6-TG reaction system with the interference ratios all below 2.8%. Under optimum conditions, a great linear relationship between fluorescence intensity function log(F0/F) and concentration of 6-TG in a wide range from 4 μM to 800 μM with a detection limit (S/N = 3) of 1.33 μM was obtained. And this proposed approach was successfully applied for the determination of 6-TG in human serum and urine samples. Furthermore, the PEI-CDs fluorescence probe has superior potential in practical application of detecting 6-TG due to its inexpensive precursors, simple operation, low toxicity and excellent biocompatibility." @default.
- W2765956218 created "2017-11-10" @default.
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- W2765956218 date "2018-02-01" @default.
- W2765956218 modified "2023-10-14" @default.
- W2765956218 title "Simple and selective determination of 6-thioguanine by using polyethylenimine (PEI) functionalized carbon dots" @default.
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- W2765956218 doi "https://doi.org/10.1016/j.talanta.2017.09.087" @default.
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