Matches in SemOpenAlex for { <https://semopenalex.org/work/W2765989345> ?p ?o ?g. }
- W2765989345 endingPage "1959" @default.
- W2765989345 startingPage "1959" @default.
- W2765989345 abstract "Epstein-Barr virus (EBV), a common pathogen in humans, is suspected as the cause of multiple pregnancy-related pathologies including depression, preeclampsia, and stillbirth. Moreover, transmission of EBV through the placenta has been reported. However, the focus of EBV infection within the placenta has remained unknown to date. In this study, we proved the expression of latent EBV genes in the endometrial glandular epithelial cells of the placenta and investigated the cytological characteristics of these cells. Sixty-eight placentas were obtained from pregnant women. Tissue microarray was constructed. EBV latent genes including EBV-encoding RNA-1 (EBER1), Epstein-Barr virus nuclear antigen 1 (EBNA1), late membrane antigen (LMP1), and RPMS1 were detected with silver in situ hybridization and/or mRNA in situ hybridization. Nuclear features of EBV-positive cells in EBV-infected placenta were compared with those of EBV-negative cells via image analysis. Sixteen placentas (23.5%) showed positive expression of all 4 EBV latent genes; only the glandular epithelial cells of the decidua showed EBV gene expression. EBV infection status was not significantly correlated with maternal, fetal, or placental factors. The nuclei of EBV-positive cells were significantly larger, longer, and round-shaped than those of EBV-negative cells regardless of EBV-infection status of the placenta. For the first time, evidence of EBV gene expression has been shown in placental tissues. Furthermore, we have characterized its cytological features, allowing screening of EBV infection through microscopic examination." @default.
- W2765989345 created "2017-11-10" @default.
- W2765989345 creator A5006659812 @default.
- W2765989345 creator A5009075091 @default.
- W2765989345 creator A5016182502 @default.
- W2765989345 creator A5027316753 @default.
- W2765989345 creator A5066138539 @default.
- W2765989345 date "2017-01-01" @default.
- W2765989345 modified "2023-09-23" @default.
- W2765989345 title "Identification of Epstein-Barr Virus in the Human Placenta and Its Pathologic Characteristics" @default.
- W2765989345 cites W1980262045 @default.
- W2765989345 cites W1997358936 @default.
- W2765989345 cites W1999180623 @default.
- W2765989345 cites W2013013791 @default.
- W2765989345 cites W2045384018 @default.
- W2765989345 cites W2056280201 @default.
- W2765989345 cites W2067138435 @default.
- W2765989345 cites W2070907961 @default.
- W2765989345 cites W2086948609 @default.
- W2765989345 cites W2093524256 @default.
- W2765989345 cites W2098494951 @default.
- W2765989345 cites W2101160153 @default.
- W2765989345 cites W2107554012 @default.
- W2765989345 cites W2113328354 @default.
- W2765989345 cites W2119370761 @default.
- W2765989345 cites W2138304797 @default.
- W2765989345 cites W2166124850 @default.
- W2765989345 cites W2168420850 @default.
- W2765989345 cites W2375428514 @default.
- W2765989345 cites W2411872420 @default.
- W2765989345 cites W2521576178 @default.
- W2765989345 cites W2605592326 @default.
- W2765989345 doi "https://doi.org/10.3346/jkms.2017.32.12.1959" @default.
- W2765989345 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5680494" @default.
- W2765989345 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29115077" @default.
- W2765989345 hasPublicationYear "2017" @default.
- W2765989345 type Work @default.
- W2765989345 sameAs 2765989345 @default.
- W2765989345 citedByCount "7" @default.
- W2765989345 countsByYear W27659893452019 @default.
- W2765989345 countsByYear W27659893452020 @default.
- W2765989345 countsByYear W27659893452021 @default.
- W2765989345 crossrefType "journal-article" @default.
- W2765989345 hasAuthorship W2765989345A5006659812 @default.
- W2765989345 hasAuthorship W2765989345A5009075091 @default.
- W2765989345 hasAuthorship W2765989345A5016182502 @default.
- W2765989345 hasAuthorship W2765989345A5027316753 @default.
- W2765989345 hasAuthorship W2765989345A5066138539 @default.
- W2765989345 hasBestOaLocation W27659893451 @default.
- W2765989345 hasConcept C104317684 @default.
- W2765989345 hasConcept C147483822 @default.
- W2765989345 hasConcept C150194340 @default.
- W2765989345 hasConcept C159047783 @default.
- W2765989345 hasConcept C172680121 @default.
- W2765989345 hasConcept C203014093 @default.
- W2765989345 hasConcept C2522874641 @default.
- W2765989345 hasConcept C2776409557 @default.
- W2765989345 hasConcept C2776953305 @default.
- W2765989345 hasConcept C2779234561 @default.
- W2765989345 hasConcept C2780197806 @default.
- W2765989345 hasConcept C2780494569 @default.
- W2765989345 hasConcept C2780727368 @default.
- W2765989345 hasConcept C2781295983 @default.
- W2765989345 hasConcept C2781375147 @default.
- W2765989345 hasConcept C2781385326 @default.
- W2765989345 hasConcept C54355233 @default.
- W2765989345 hasConcept C81439078 @default.
- W2765989345 hasConcept C86803240 @default.
- W2765989345 hasConceptScore W2765989345C104317684 @default.
- W2765989345 hasConceptScore W2765989345C147483822 @default.
- W2765989345 hasConceptScore W2765989345C150194340 @default.
- W2765989345 hasConceptScore W2765989345C159047783 @default.
- W2765989345 hasConceptScore W2765989345C172680121 @default.
- W2765989345 hasConceptScore W2765989345C203014093 @default.
- W2765989345 hasConceptScore W2765989345C2522874641 @default.
- W2765989345 hasConceptScore W2765989345C2776409557 @default.
- W2765989345 hasConceptScore W2765989345C2776953305 @default.
- W2765989345 hasConceptScore W2765989345C2779234561 @default.
- W2765989345 hasConceptScore W2765989345C2780197806 @default.
- W2765989345 hasConceptScore W2765989345C2780494569 @default.
- W2765989345 hasConceptScore W2765989345C2780727368 @default.
- W2765989345 hasConceptScore W2765989345C2781295983 @default.
- W2765989345 hasConceptScore W2765989345C2781375147 @default.
- W2765989345 hasConceptScore W2765989345C2781385326 @default.
- W2765989345 hasConceptScore W2765989345C54355233 @default.
- W2765989345 hasConceptScore W2765989345C81439078 @default.
- W2765989345 hasConceptScore W2765989345C86803240 @default.
- W2765989345 hasIssue "12" @default.
- W2765989345 hasLocation W27659893451 @default.
- W2765989345 hasLocation W27659893452 @default.
- W2765989345 hasLocation W27659893453 @default.
- W2765989345 hasOpenAccess W2765989345 @default.
- W2765989345 hasPrimaryLocation W27659893451 @default.
- W2765989345 hasRelatedWork W2006558559 @default.
- W2765989345 hasRelatedWork W2030238129 @default.
- W2765989345 hasRelatedWork W2040291358 @default.
- W2765989345 hasRelatedWork W2042712871 @default.
- W2765989345 hasRelatedWork W2080705679 @default.