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- W2766009600 abstract "Background With the availability of raw DNA generated from direct-to-consumer (DTC) testing companies, there has been a proliferation of third-party online services that are available to interpret the raw data for both genealogy and/or health purposes. This study examines the current landscape and downstream clinical implications of consumer use of third-party services. Methods Study participants were recruited online from social media platforms. A total of 321 survey respondents reported using third-party services for raw DNA interpretation. Results Participants were highly motivated to explore raw DNA for ancestral information (67%), individual health implications (62%), or both (40%). Participants primarily used one of seven companies to interpret raw DNA; 73% used more than one. Company choice was driven by the type of results offered (51%), price (45%), and online reviews (31%). Approximately 30% of participants shared results with a medical provider and 21% shared with more than one. Outcomes of sharing ranged from disinterest/discounting of the information to diagnosis of genetic conditions. Participants were highly satisfied with their decision to analyze raw DNA (M = 4.54/5), yet challenges in understanding interpretation results were reported irrespective of satisfaction ratings. Conclusion Consumers face challenges in understanding the results and may seek out clinical assistance in interpreting their raw DNA results." @default.
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- W2766009600 date "2017-11-02" @default.
- W2766009600 modified "2023-10-17" @default.
- W2766009600 title "Consumer use and response to online third-party raw DNA interpretation services" @default.
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- W2766009600 doi "https://doi.org/10.1002/mgg3.340" @default.
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