FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2766130635> ?p ?o ?g. }

• W2766130635 endingPage "184" @default.
• W2766130635 startingPage "178" @default.
• W2766130635 abstract "Alcohol use disorder (AUD) is a frequent comorbidity among people living with HIV/AIDS (PLWHA). Alcohol consumption is a significant predictor of nonadherence to antiretroviral therapy (ART), as well as worsening immunological and virological indicators among PLWHA. Clinical studies indicate that higher viral loads increase sensitivity to alcohol in PLWHA. The factors that influence alcohol kinetics after HIV infection and initiation of ART are not well understood, limiting the information upon which interventions can be designed to ameliorate the impact of alcohol misuse on this vulnerable patient population. To better understand the relationship between viral load and alcohol kinetics, we measured changes in doses of intragastric ethanol administration to achieve target blood ethanol concentration (BEC) in a rhesus macaque model of chronic binge alcohol (CBA) administration and acute changes following a single acute binge dose of alcohol (ABA) pre- and post-simian immunodeficiency virus (SIV) infection, and following ART initiation. Our results from CBA (14 months)-administered SIV-infected male macaques showed that, following ART initiation, macaques required higher doses of alcohol to achieve a target peak BEC compared with non-ART-treated SIV-infected macaques. In animals given ABA, we found prolonged duration of elevated BEC and decreased elimination rate of alcohol that was not corrected following 7 weeks of ART. These findings suggest that binge drinking associated with AUD could negatively interact with HIV infection and enhance disease progression. These findings further support the need for implementation of behavioral or therapeutic interventions to decrease alcohol consumption to improve the quality of life in PLWHA." @default.
• W2766130635 created "2017-11-10" @default.
• W2766130635 creator A5005778835 @default.
• W2766130635 creator A5014007269 @default.
• W2766130635 creator A5025821325 @default.
• W2766130635 creator A5027281273 @default.
• W2766130635 creator A5029247654 @default.
• W2766130635 creator A5034779404 @default.
• W2766130635 creator A5049339126 @default.
• W2766130635 creator A5061526145 @default.
• W2766130635 creator A5062460775 @default.
• W2766130635 creator A5068516229 @default.
• W2766130635 creator A5075838086 @default.
• W2766130635 creator A5086871896 @default.
• W2766130635 date "2018-02-01" @default.
• W2766130635 modified "2023-09-23" @default.
• W2766130635 title "Simian Immunodeficiency Virus Infection Increases Blood Ethanol Concentration Duration After Both Acute and Chronic Administration" @default.
• W2766130635 cites W1164997755 @default.
• W2766130635 cites W1510446167 @default.
• W2766130635 cites W1849247882 @default.
• W2766130635 cites W1858418996 @default.
• W2766130635 cites W1968511072 @default.
• W2766130635 cites W1972738289 @default.
• W2766130635 cites W1974898567 @default.
• W2766130635 cites W2005619268 @default.
• W2766130635 cites W2020898304 @default.
• W2766130635 cites W2036505093 @default.
• W2766130635 cites W2043875131 @default.
• W2766130635 cites W2053178989 @default.
• W2766130635 cites W2063647809 @default.
• W2766130635 cites W2076884514 @default.
• W2766130635 cites W2082347526 @default.
• W2766130635 cites W2083244920 @default.
• W2766130635 cites W2122999152 @default.
• W2766130635 cites W2321805999 @default.
• W2766130635 cites W2515602957 @default.
• W2766130635 doi "https://doi.org/10.1089/aid.2017.0195" @default.
• W2766130635 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5806079" @default.
• W2766130635 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29037050" @default.
• W2766130635 hasPublicationYear "2018" @default.
• W2766130635 type Work @default.
• W2766130635 sameAs 2766130635 @default.
• W2766130635 citedByCount "8" @default.
• W2766130635 countsByYear W27661306352018 @default.
• W2766130635 countsByYear W27661306352019 @default.
• W2766130635 countsByYear W27661306352020 @default.
• W2766130635 countsByYear W27661306352021 @default.
• W2766130635 countsByYear W27661306352023 @default.
• W2766130635 crossrefType "journal-article" @default.
• W2766130635 hasAuthorship W2766130635A5005778835 @default.
• W2766130635 hasAuthorship W2766130635A5014007269 @default.
• W2766130635 hasAuthorship W2766130635A5025821325 @default.
• W2766130635 hasAuthorship W2766130635A5027281273 @default.
• W2766130635 hasAuthorship W2766130635A5029247654 @default.
• W2766130635 hasAuthorship W2766130635A5034779404 @default.
• W2766130635 hasAuthorship W2766130635A5049339126 @default.
• W2766130635 hasAuthorship W2766130635A5061526145 @default.
• W2766130635 hasAuthorship W2766130635A5062460775 @default.
• W2766130635 hasAuthorship W2766130635A5068516229 @default.
• W2766130635 hasAuthorship W2766130635A5075838086 @default.
• W2766130635 hasAuthorship W2766130635A5086871896 @default.
• W2766130635 hasBestOaLocation W27661306352 @default.
• W2766130635 hasConcept C126322002 @default.
• W2766130635 hasConcept C142462285 @default.
• W2766130635 hasConcept C203014093 @default.
• W2766130635 hasConcept C2522874641 @default.
• W2766130635 hasConcept C2776679223 @default.
• W2766130635 hasConcept C2777995582 @default.
• W2766130635 hasConcept C2779159551 @default.
• W2766130635 hasConcept C2779442783 @default.
• W2766130635 hasConcept C2779690655 @default.
• W2766130635 hasConcept C2780161600 @default.
• W2766130635 hasConcept C2780727368 @default.
• W2766130635 hasConcept C2781066024 @default.
• W2766130635 hasConcept C2908647359 @default.
• W2766130635 hasConcept C3019635848 @default.
• W2766130635 hasConcept C55493867 @default.
• W2766130635 hasConcept C71924100 @default.
• W2766130635 hasConcept C86803240 @default.
• W2766130635 hasConcept C99454951 @default.
• W2766130635 hasConceptScore W2766130635C126322002 @default.
• W2766130635 hasConceptScore W2766130635C142462285 @default.
• W2766130635 hasConceptScore W2766130635C203014093 @default.
• W2766130635 hasConceptScore W2766130635C2522874641 @default.
• W2766130635 hasConceptScore W2766130635C2776679223 @default.
• W2766130635 hasConceptScore W2766130635C2777995582 @default.
• W2766130635 hasConceptScore W2766130635C2779159551 @default.
• W2766130635 hasConceptScore W2766130635C2779442783 @default.
• W2766130635 hasConceptScore W2766130635C2779690655 @default.
• W2766130635 hasConceptScore W2766130635C2780161600 @default.
• W2766130635 hasConceptScore W2766130635C2780727368 @default.
• W2766130635 hasConceptScore W2766130635C2781066024 @default.
• W2766130635 hasConceptScore W2766130635C2908647359 @default.
• W2766130635 hasConceptScore W2766130635C3019635848 @default.
• W2766130635 hasConceptScore W2766130635C55493867 @default.
• W2766130635 hasConceptScore W2766130635C71924100 @default.
• W2766130635 hasConceptScore W2766130635C86803240 @default.
• W2766130635 hasConceptScore W2766130635C99454951 @default.

• next