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- W2766221230 abstract "Aim: We sought to study the responses of dendritic cells (DCs) after direct stimulation by different influenza A viruses. Materials & methods: Using bone marrow-derived DCs (BMDCs) as a model, we measured the expression of surface markers, cytokine production and the priming effect on CD4 + naive T cells. Results & conclusion: We found that all of the tested viruses induced BMDC maturation. Cytokine expression assays also demonstrated that activated BMDCs secrete higher levels of cytokines. Similar to the maturation degree, well-stimulated BMDCs induced higher levels of naive CD4 + T-cell activation. Furthermore, we found that the PR8 and WSN influenza A viruse-induced BMDC functional activation was at least partially influenced by autophagy." @default.
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- W2766221230 date "2017-11-01" @default.
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- W2766221230 title "Differential immune response of influenza A virus-infected dendritic cells and association with autophagy" @default.
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- W2766221230 doi "https://doi.org/10.2217/fvl-2017-0044" @default.
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